Cell's fight against cancer revealed
If anything in cancer biology can be likened to a cage match, this is it: the battle inside the cell walls between LTag, "The Most Amazing Molecule in the Universe," and p53, "The Guardian of the Genome." view more (2006-09-01)
Structure of key enzyme in plague bacterium found
Researchers at the National Institute of Standards and Technology (NIST) have solved the structure of a key enzyme from the bacterium responsible for plague, finding that it has a highly unusual configuration. The results may shed light both on how the bacterium kills and on fundamental cell signaling processes. view more (2006-08-21)
Collaborative study successfully applies neutrons to study hydrogen transfer in biological systems
An innovative collaboration among scientists at Los Alamos National Laboratory, Fox Chase Cancer Center and the University of Tennessee has successfully applied neutron diffraction to create a three-dimensional map of the structure of the enzyme D-xylose isomerase. view more (2006-05-16)
Key heart and Alzheimer's disease protein imaged for first time in native state
Researchers for the first time have created a three-dimensional image of apolipoprotein E, a protein long associated with cardiovascular disease and more recently with Alzheimer's disease, as it appears when it is bound to fat-like substances known as lipids. view more (2006-01-16)
Molecule does more than slice and dice RNA
A team of Howard Hughes Medical Institute (HHMI) scientists has peeled back some of the mystery of how cells are able to turn off genes selectively to control critical events of development. view more (2006-01-13)
Scientists make first step towards 'holy grail' of crystallography
Scientists from Imperial College London and the University of Surrey have developed a new technique for crystallising proteins, a discovery which could help speed up the development of new medicines and treatments. view more (2006-01-09)
Zooming in on the protein-conducting channel
Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane. view more (2005-11-17)
Metal-containing compounds show promise as HIV weapon
A molecule consisting of two "cages" of metallic atoms bound to carbon has shown great promise in preliminary tests of becoming a new weapon in the anti-HIV arsenal, researchers at UT Southwestern Medical Center report. view more (2005-11-01)
Structure of key cancer drug target identified
Researchers from Monash's Department of Biochemistry and Molecular Biology have determined the structure of the protein JAK2 kinase, a discovery with huge implications for the design and development of new cancer drugs. view more (2005-10-26)
Progress toward a new remedy for chronic urinary tract infections?
Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) at the Free University of Brussels have recently published results that show promise in the quest for a new remedy for chronic urinary tract infections. The researchers have shown that administration of the sugar Heptyl-a-D-mannoside can prevent E. coli bacteria from... view more... (2005-02-10)
10 Million Euro Technology Project Makes Europe a leader in Biocrystallography
A project to create a common platform throughout Europe for researchers working in the field of 'biological crystallography' is underway thanks to a grant of 10 million euros from the EU's 6th Framework Programme (FP6). view more (2005-02-08)
Media Invitation: 20 years of excellence - Catch-up on the latest news from ISIS and tour the facility
ISIS celebrates 20 years of excellence view more (2004-12-06)
European researchers launch 10 million Euro collaborative technology project
European researchers launch 10 million Euro collaborative technology project: EMBL-Hamburg coordinates a four-year integrated research project within the 6th Framework Programme of the European Commission: The European Commission has given Europe a huge boost in the field of Structural Genomics, awarding the European Molecular Biology Laboratory... view more... (2004-02-12)
The structure of a key enzyme for infectious diseases solved at ESRF
A European team of scientists from the University of Dundee (UK), the Technical University of Munich (Germany) and the European Synchrotron Radiation Facility, ESRF, (France) have determined the structure of a key target enzyme for novel drug development to treat infectious diseases including malaria, tuberculosis and sexually transmitted... view more... (2003-08-12)
First structure of transporter enzyme family is solved - Finding will aid drug design to combat depression, stroke and diabetes
Scientists are a step closer to understanding how essential nutrients, vitamins and minerals are ferried into cells. For the first time, a member of the Major Facilitator Superfamily (MFS) of transport proteins, found in almost every form of life, has been visualised by researchers from Imperial College London and the University of California, Los... view more... (2003-07-30)
Chemistry & Industry Magazine - cover date 7 July 2003
NEWS The most toxic conflict Recent advances in the research into Gulf war syndrome means that soldiers returning from the latest conflict may be more fortunate than those returning after 1991. But how much are UK soldiers going to benefit from these advances? The UK spends a lot less than the US on research into the syndrome and unlike UK troops,... view more... (2003-07-03)
Filming an ultra-fast biological reaction essential to life
A team of scientists from the USA in collaboration with staff at the European Synchrotron Radiation Facility1 (Schotte et al) have managed to film a protein at work in unprecedented detail. The protein is the oxygen-storing molecule myoglobin, which plays a central role in the production of energy in muscles. The motion of the protein was recorded... view more... (2003-06-24)
RTS and Syrrx Announce Partnership
RTS Life Science International (RTS) and Syrrx announce a partnership to develop and market high throughput structural biology automation solutions. This will be known as the HTSB Factory™ and it allows the user to set-up hundreds of thousands of experiments for a target and increase the crystallization rate significantly. Dr. Wendell... view more... (2003-05-01)
RiboTargets joins Partnership for Structural Biology at the European Synchrotron Radiation Facility
RiboTargets, the structure-based drug discovery company that develops novel cancer and anti-bacterial therapeutics, announced today that it has joined the new Partnership for Structural Biology (PSB) established at the European Synchrotron Radiation Facility (ESRF). Associate membership of the PSB will provide guaranteed access to beamlines at... view more... (2003-01-24)
Mammoth project reveals frozen secrets
Which way does a mammoth skeleton point in Siberia? No, it’s not a Christmas cracker joke. To find the answer you have to look in a rather surprising place – the Institute of Physics’ new online archive. In an article published in the first edition of Proceedings of the Physical Society in 1874, John Rae writes about the... view more... (2003-01-08)
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