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Do financial interests result in positive results in scientific research?
Virtually all (94%) of the scientific authors who provided positive results for the anti-diabetic drug rosiglitazone had financial relationships with pharmaceutical companies.   view more (2010-03-19)

LSUHSC research increases understanding of drug metabolism
Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes are present in an individual, but also how they interact, and that can be the difference in whether a drug is safely... view more... (2010-03-18)

Childhood adversity may promote cellular aging
Children who suffer physical or emotional abuse could be faced with accelerated cellular aging as adults, according to new research published by Elsevier in Biological Psychiatry.   view more (2010-03-17)

Researchers ID brain abnormalities in children exposed to methamphetamine in utero
It has long been known that alcohol exposure is toxic to the developing fetus and can result in lifelong brain, cognitive and behavioral problems.   view more (2010-03-17)

Smoking, but not past alcohol abuse, may impair mental function
Men and women with a history of alcohol abuse may not see long-term negative effects on their memory and thinking, but female smokers do, a new study suggests.    view more (2010-03-16)

Impulsive-Antisocial Personality Traits Linked to a Hypersensitive Brain Reward System
Normal individuals who scored high on a measure of impulsive/antisocial traits display a hypersensitive brain reward system, according to a brain imaging study by researchers at Vanderbilt University.   view more (2010-03-16)

Psychopaths' brains wired to seek rewards, no matter the consequences
The brains of psychopaths appear to be wired to keep seeking a reward at any cost, new research from Vanderbilt University finds. The research uncovers the role of the brain's reward system in psychopathy and opens a new area of study for understanding what drives these individuals.    view more (2010-03-15)

New drug candidate reduces blood lipids
A thyroid-hormone-like substance that works specifically on the liver reduces blood cholesterol with no serious side effects.    view more (2010-03-11)

Male batterers consistently overestimate rates of violence toward partners
Men who engaged in domestic violence consistently overestimated how common such behavior is, and the more they overestimated it the more they engaged in abusing their partner in the previous 90 days, according to new research conducted at the University of Washington.    view more (2010-03-10)

UM School of Medicine finds prenatal cocaine exposure not severely damaging to growth, learning
Children exposed to cocaine in the womb face serious consequences from the drug, but fortunately not in certain critical physical and cognitive areas as previously believed, according to a new comprehensive review of research on the subject from scientists at the University of Maryland School of Medicine.   view more (2010-03-02)

Increasing neurogenesis might prevent drug addiction and relapse
Researchers at UT Southwestern Medical Center hope they have begun paving a new pathway in the fight against drug dependence. Their hypothesis - that increasing the normally occurring process of making nerve cells might prevent addiction - is based on a rodent study demonstrating that blocking new growth of specific brain nerve cells increases... view more... (2010-03-01)

Inadequate access to opioid-based pain relief is a human rights issue for cancer patients
Many cancer patients in Europe are being denied access to adequate pain relief because of over-zealous regulations restricting the availability and accessibility of opioid-based drugs such as morphine.    view more (2010-02-22)

Transforming skin cells into stem cells using a molecular toolkit
In an effort to sidestep the ethical dilemma involved in using human embryonic stem cells to treat diseases, scientists are developing non-controversial alternatives: In particular, they are looking for drug-like chemical compounds that can transform adult skin cells into the stem cells now obtained from human embryos.   view more (2010-02-19)

U-M researchers find key interaction that controls telomeres
In the dominoes that make up human cells, researchers at the University of Michigan Comprehensive Cancer Center have traced another step of the process that stops cells from becoming cancerous.   view more (2010-02-17)

Researchers create drug to keep tumor growth switched off
A novel - and rapid - anti-cancer drug development strategy has resulted in a new drug that stops kidney and pancreatic tumors from growing in mice.   view more (2010-02-12)

Drug shows promise for Huntington's disease
An early stage clinical trial of the experimental drug dimebon (latrepirdine) in people with Huntington's disease appears to be safe and may improve cognition. That is the conclusion of a study published today in the Archives of Neurology.    view more (2010-02-09)

Cocaine or ecstasy consumption during adolescence increases risk of addiction
Exposure to ecstasy or cocaine during adolescence increases the "reinforcing effects" that make people vulnerable to developing an addiction.   view more (2010-02-05)

Early abuse tied to more depression in children
Although children can be depressed for many reasons, new evidence suggests that there are physiological differences among depressed children based on their experiences of abuse before age 5.   view more (2010-02-05)

Brain dopamine receptor density correlates with social status
People have typically viewed the benefits that accrue with social status primarily from the perspective of external rewards. A new paper in the February 1st issue of Biological Psychiatry, published by Elsevier suggests that there are internal rewards as well.   view more (2010-02-04)

Iowa State, Ames Lab chemists discover how antiviral drugs bind to and block flu virus
Antiviral drugs block influenza A viruses from reproducing and spreading by attaching to a site within a proton channel necessary for the virus to infect healthy cells, according to a research project led by Iowa State University's Mei Hong and published in the Feb. 4 issue of the journal Nature.   view more (2010-02-04)
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