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Do financial interests result in positive results in scientific research?
Virtually all (94%) of the scientific authors who provided positive results for the anti-diabetic drug rosiglitazone had financial relationships with pharmaceutical companies. view more (2010-03-19)
LSUHSC research increases understanding of drug metabolism
Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes are present in an individual, but also how they interact, and that can be the difference in whether a drug is safely... view more... (2010-03-18)
DNA nanotechnology breakthrough offers promising applications in medicine
A team of McGill Chemistry Department researchers led by Dr. Hanadi Sleiman has achieved a major breakthrough in the development of nanotubes - tiny "magic bullets" that could one day deliver drugs to specific diseased cells. view more (2010-03-18)
Blocking cancer in its path: New cellular defect discovered
UCSF researchers have discovered that a key cellular defect that disturbs the production of proteins in human cells can lead to cancer susceptibility. view more (2010-03-17)
Movement disorder symptoms are lessened by an antibiotic
Discovery of an antibiotic's capacity to improve cell function in laboratory tests is providing movement disorder researchers with leads to more desirable molecules with potentially similar traits. view more (2010-03-11)
New drug candidate reduces blood lipids
A thyroid-hormone-like substance that works specifically on the liver reduces blood cholesterol with no serious side effects. view more (2010-03-11)
Intentional variation increases result validity in mouse testing
For decades, the traditional practice in animal testing has been standardization, but a study involving Purdue University has shown that adding as few as two controlled environmental variables to preclinical mice tests can greatly reduce costly false positives, the number of animals needed for testing and the cost of pharmaceutical trials. view more (2010-03-10)
Snake venom charms science world
The King Cobra continues to weave its charm with researchers identifying a protein in its venom with the potential for new drug discovery and to advance understanding of disease mechanisms. view more (2010-03-08)
How to hunt for exoplanets
A new report launched by the Institute of Physics (IOP) Exoplanets - The search for planets beyond our solar system explains how new technological advances have seen the discovery of more than 400 exoplanets to date, a number expected to rise to thousands in the next few years. view more (2010-03-03)
A new generation of rapid-acting antidepressants?
Conventional antidepressant treatments generally require three to four weeks to become effective, thus the discovery of treatments with a more rapid onset is a major goal of biological psychiatry. view more (2010-03-02)
First discovery of the female sex hormone progesterone in a plant
In a finding that overturns conventional wisdom, scientists are reporting the first discovery of the female sex hormone progesterone in a plant. view more (2010-02-25)
New cancer-fighting strategy focuses on signaling molecules
Cancer researchers studying the immune system have identified a previously unrecognized set of targets and biomarkers to battle solid tumors. view more (2010-02-25)
Enzyme deficiency protects hepatitis C patients from treatment-related anemia
Many people who undergo treatment for hepatitis C develop hemolytic anemia, a disorder that destroys red blood cells. view more (2010-02-22)
Transforming skin cells into stem cells using a molecular toolkit
In an effort to sidestep the ethical dilemma involved in using human embryonic stem cells to treat diseases, scientists are developing non-controversial alternatives: In particular, they are looking for drug-like chemical compounds that can transform adult skin cells into the stem cells now obtained from human embryos. view more (2010-02-19)
Nanotech discovery may green chemical manufacturing
A new nanotech catalyst developed by McGill University Chemists Chao-Jun Li, Audrey Moores and their colleagues offers industry an opportunity to reduce the use of expensive and toxic heavy metals. view more (2010-02-17)
U-M researchers find key interaction that controls telomeres
In the dominoes that make up human cells, researchers at the University of Michigan Comprehensive Cancer Center have traced another step of the process that stops cells from becoming cancerous. view more (2010-02-17)
Genomic warfare to counter malaria drug resistance
Scientists battling malaria have earned a major victory. According to a Nature Genetics study, an international group of researchers has used genomics to decode the blueprint of Plasmodium falciparum - a strain of malaria most resistant to drugs that causes the most deaths around the world. view more (2010-02-17)
OHSU researchers discover cellular mechanism that protects against disease
Researchers at Oregon Health & Science University have discovered a new mechanism within human cells that constantly protects us against disease. P. Michael Conn, Ph.D., a researcher at the OHSU Oregon National Primate Research Center directed the work. view more (2010-02-16)
Researchers create drug to keep tumor growth switched off
A novel - and rapid - anti-cancer drug development strategy has resulted in a new drug that stops kidney and pancreatic tumors from growing in mice. view more (2010-02-12)
New screening system for hepatitis C
A newly designed system of identifying molecules for treating hepatitis C should enable scientists to discover novel and effective therapies for the dangerous and difficult-to-cure disease of the liver, says Zhilei Chen, a Texas A&M University assistant professor of chemical engineering who helped develop the screening system. view more (2010-02-12)
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