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A scientific breakthrough on the control of the bad cholesterol
A study performed by the team of Dr. Nabil G. Seidah, Director of the Biochemical Neuroendocrinology Research Unit at the IRCM, shows for the very first time that the degradation by PCSK9 of the LDLR receptor   view more (2008-11-25)

Scientists Present 'Moving' Theory Behind Bacterial Decision-Making
Biochemists at North Carolina State University have answered a fundamental question of how important bacterial proteins make life-and-death decisions that allow them to function, a finding that could provide a new target for drugs to disrupt bacterial decision-making processes and related diseases.   view more (2008-11-25)

Heart patients are often not treated in accordance with guidelines
Many patients with cardiovascular disease are not given adequate drug therapy. This is the result of an international study. In the current edition of Deutsches Ärzteblatt International, Uwe Zeimer et al. present the German results of this prospective, one-year survey.   view more (2008-11-24)

UT Southwestern researchers develop new strategy for broad spectrum anti-viral drugs
Bavituximab, an anti-viral drug developed by UT Southwestern Medical Center researchers, shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents.   view more (2008-11-24)

Iressa proves just as effective as chemotherapy for lung cancer
Gefitinib, also known as Iressa, the once-promising targeted therapy for the treatment of non-small cell lung cancer, has proven as effective as chemotherapy as a second-line therapy for the disease with far fewer side effects, according to an international Phase III clinical trial, led by... view more (2008-11-21)

Garlic chemical tablet treats diabetes I and II
A drug based on a chemical found in garlic can treat diabetes types I and II when taken as a tablet, a study in the new Royal Society of Chemistry journal Metallomics says.   view more (2008-11-20)

New platinum-phosphate compounds kill ovarian cancer cells
A new class of compounds called phosphaplatins can effectively kill ovarian, testicular, head and neck cancer cells with potentially less toxicity than conventional drugs, according to a new study published this week in the journal Proceedings of the National Academy of Sciences.    view more (2008-11-20)

Stopping germs from ganging up on humans
Keeping germs from cooperating can delay the evolution of drug resistance more effectively than killing germs one by one with traditional drugs such as antibiotics, according to new research from The University of Arizona in Tucson.   view more (2008-11-20)

Scientists exploring new compounds to target muscular dystrophy
Scientists have identified a promising set of new compounds in the fight against muscular dystrophy.   view more (2008-11-19)

Conference report highlights new research into drug delivery to treat eye disease
Researchers are investigating microneedles, nanoparticles and polymer carriers as potential new techniques to combat the leading cause of visual impairment and blindness in the United States, according to a report from the Third Annual ARVO/Pfizer Ophthalmics Research Institute Conference.   view more (2008-11-18)

Biomedical engineers' detective work reveals antibiotic mechanism
A series of genetic clues led a team of Boston University biomedical engineers to uncover exactly how certain antibiotics kill bacteria. The findings could help rejuvenate the efficacy of older antibiotics and reveal new antibiotic targets within bacterial cells.   view more (2008-11-18)

Simple new method detects contaminants in life-saving drug
The blood-thinning drug heparin is highly effective when used to prevent and treat blood clots in veins, arteries and lungs, but earlier this year its reputation as a lifesaver was sullied when contaminated heparin products caused serious allergic reactions that led to a large number of deaths.   view more (2008-11-18)

Hope for treating relapse to methamphetamine abuse
A new study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory suggests that vigabatrin (a.k.a. gamma vinyl-GABA, or GVG) blocks drug-seeking behavior in animals previously trained to associate methamphetamine with a particular environment.   view more (2008-11-13)

OHSU Knight Cancer Institute researcher: study may result in more targeted drugs for GIST
According to Oregon Health & Science University Knight Cancer Institute researchers, there is strong evidence that patients can have varying clinical responses to medications depending on the specific makeup of their cancer.   view more (2008-11-13)

Novel 4-drug combination proves safe for lung cancer treatment
The four drug-combination of carboplatin and paclitaxel, with the targeted therapies bevacizumab (Avastin) and cetuximab (Erbitux), is safe and may improve survival for patients with advanced lung cancer, according to a cooperative group study led by The University of Texas M. D. Anderson Cancer... view more (2008-11-13)

Forced evolution: Can we mutate viruses to death?
It sounds like a science fiction movie: A killer contagion threatens the Earth, but scientists save the day with a designer drug that forces the virus to mutate itself out of existence. The killer disease? Still a fiction. The drug? It could become a reality thanks to a new study by Rice University... view more (2008-11-11)

Engineered killer T cell recognizes HIV-1's lethal molecular disguises
Researchers at the University of Pennsylvania School of Medicine and colleagues in the United Kingdom have engineered T cells able to recognize HIV-1 strains that have evaded the immune system.   view more (2008-11-10)

Study reveals continued damage from banned obesity drug
Fenfluramine, the appetite suppressant drug banned in the US in 1997 due to fears over its links to heart conditions, has been shown to have serious long-term effects.   view more (2008-11-06)

Pitt research identifies new target in brain for treating schizophrenia
Research from the University of Pittsburgh could expand the options for controlling schizophrenia by identifying a brain region that responds to more than one type of antipsychotic drug.   view more (2008-11-06)

Drug mimics low-cal diet to ward off weight gain, boost running endurance
A drug designed to specifically hit a protein linked to the life-extending benefits of a meager diet can essentially trick the body into believing food is scarce even when it isn't, suggests a new report in the November Cell Metabolism.   view more (2008-11-05)

An Anti-Frailty Pill for Seniors?
Researchers at the University of Virginia Health System report that a daily single oral dose of an investigational drug, MK-677, increased muscle mass in the arms and legs of healthy older adults without serious side effects, suggesting that it may prove safe and effective in reducing age-related... view more (2008-11-05)

Can berberine enhance glucose-stimulated insulin secretion in rat islets?
The therapeutical actions of berberine on diabetes have been well studied. Previous researches show that berberine modulates cholesterol through increasing low-density lipoprotein receptor mRNA stability, reduces body adiposity and increases insulin sensitivity partly through activating... view more (2008-11-03)

Iowa State researcher develops new treatment method for canine eye diseases
An Iowa State University researcher is exploring a new method of getting medicine to the eyes of infected dogs that is more effective and reliable than using eye drops.   view more (2008-10-29)

NJIT professor finds engineering technique to identify disease-causing genes
Scientists believe that complex diseases such as schizophrenia, major depression and cancer are not caused by one, but a multitude of dysfunctional genes.   view more (2008-10-29)

Moderate use averts failure of type 2 diabetes drugs in animal model
Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at Washington University School of Medicine in St. Louis have found in a study using an animal model.   view more (2008-10-28)
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