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A scientific breakthrough on the control of the bad cholesterol
A study performed by the team of Dr. Nabil G. Seidah, Director of the Biochemical Neuroendocrinology Research Unit at the IRCM, shows for the very first time that the degradation by PCSK9 of the LDLR receptor   view more (2008-11-25)

Heart patients are often not treated in accordance with guidelines
Many patients with cardiovascular disease are not given adequate drug therapy. This is the result of an international study. In the current edition of Deutsches Ärzteblatt International, Uwe Zeimer et al. present the German results of this prospective, one-year survey.   view more (2008-11-24)

UT Southwestern researchers develop new strategy for broad spectrum anti-viral drugs
Bavituximab, an anti-viral drug developed by UT Southwestern Medical Center researchers, shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents.   view more (2008-11-24)

Garlic chemical tablet treats diabetes I and II
A drug based on a chemical found in garlic can treat diabetes types I and II when taken as a tablet, a study in the new Royal Society of Chemistry journal Metallomics says.   view more (2008-11-20)

Stopping germs from ganging up on humans
Keeping germs from cooperating can delay the evolution of drug resistance more effectively than killing germs one by one with traditional drugs such as antibiotics, according to new research from The University of Arizona in Tucson.   view more (2008-11-20)

Conference report highlights new research into drug delivery to treat eye disease
Researchers are investigating microneedles, nanoparticles and polymer carriers as potential new techniques to combat the leading cause of visual impairment and blindness in the United States, according to a report from the Third Annual ARVO/Pfizer Ophthalmics Research Institute Conference.   view more (2008-11-18)

Simple new method detects contaminants in life-saving drug
The blood-thinning drug heparin is highly effective when used to prevent and treat blood clots in veins, arteries and lungs, but earlier this year its reputation as a lifesaver was sullied when contaminated heparin products caused serious allergic reactions that led to a large number of deaths.   view more (2008-11-18)

Hope for treating relapse to methamphetamine abuse
A new study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory suggests that vigabatrin (a.k.a. gamma vinyl-GABA, or GVG) blocks drug-seeking behavior in animals previously trained to associate methamphetamine with a particular environment.   view more (2008-11-13)

Novel 4-drug combination proves safe for lung cancer treatment
The four drug-combination of carboplatin and paclitaxel, with the targeted therapies bevacizumab (Avastin) and cetuximab (Erbitux), is safe and may improve survival for patients with advanced lung cancer, according to a cooperative group study led by The University of Texas M. D. Anderson Cancer... view more (2008-11-13)

Forced evolution: Can we mutate viruses to death?
It sounds like a science fiction movie: A killer contagion threatens the Earth, but scientists save the day with a designer drug that forces the virus to mutate itself out of existence. The killer disease? Still a fiction. The drug? It could become a reality thanks to a new study by Rice University... view more (2008-11-11)

Study reveals continued damage from banned obesity drug
Fenfluramine, the appetite suppressant drug banned in the US in 1997 due to fears over its links to heart conditions, has been shown to have serious long-term effects.   view more (2008-11-06)

Drug mimics low-cal diet to ward off weight gain, boost running endurance
A drug designed to specifically hit a protein linked to the life-extending benefits of a meager diet can essentially trick the body into believing food is scarce even when it isn't, suggests a new report in the November Cell Metabolism.   view more (2008-11-05)

An Anti-Frailty Pill for Seniors?
Researchers at the University of Virginia Health System report that a daily single oral dose of an investigational drug, MK-677, increased muscle mass in the arms and legs of healthy older adults without serious side effects, suggesting that it may prove safe and effective in reducing age-related... view more (2008-11-05)

Iowa State researcher develops new treatment method for canine eye diseases
An Iowa State University researcher is exploring a new method of getting medicine to the eyes of infected dogs that is more effective and reliable than using eye drops.   view more (2008-10-29)

Moderate use averts failure of type 2 diabetes drugs in animal model
Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at Washington University School of Medicine in St. Louis have found in a study using an animal model.   view more (2008-10-28)

Epilepsy drug may help Alzheimer's patients
A popular epilepsy drug may also be beneficial in patients with Alzheimer's disease (AD), according to a new study to be published on October 27 in the Journal of Experimental Medicine. The anti-seizure drug valproic acid improved memory and reduced brain lesions in mice with an AD-like disease.   view more (2008-10-27)

DNA research taking guesswork out of finding the 'therapeutic window'
It's only spit, but what's inside your saliva may help solve a dosing dilemma facing doctors and patients.   view more (2008-10-24)

Self-assembling nano-fiber gel delivers high concentrations of clinically approved drugs
Two teams of scientists from Harvard-MIT Division of Health Science and Technology (HST) at Brigham and Women's Hospital have developed a new self-assembling hydrogel drug delivery system that is biocompatible, efficient at drug release, and easy to tailor.   view more (2008-10-22)

Getting to grips with the complexity of disease proteins
Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these 'cooperative assemblies' should lead to better targeting of drugs.   view more (2008-10-21)

Drug-eluting stents more effective, equally as safe as bare metal stents in clinical trial
Late-breaking data from the HORIZONS AMI (Harmonizing Outcomes with RevascularIZatiON and Stents in Acute Myocardial Infarction) trial reveal that after one year, use of a drug-eluting (paclitaxel) stent demonstrated significantly reduced rates of target lesion revascularization (TLR) and binary... view more (2008-10-16)

HORIZONS AMI will help set guidelines for drug and stent therapy
The HORIZONS AMI clinical trial measuring the safety and efficacy of the use of the medication bivalirudin compared to standard drug therapy - heparin and glycoprotein IIb/IIIa inhibitors -- in heart attack patients who receive angioplasty, found that after 1 year, use of bivalirudin resulted in... view more (2008-10-16)

Drug may reduce coronary artery plaque
Research presented at the 20th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation (CRF), suggests that olmesartan, a drug commonly used to treat high blood pressure, may play a role in reducing coronary plaque.   view more (2008-10-13)

Body's anti-HIV drug explained
Humans have a built-in weapon against HIV, but until recently no one knew how to unlock its potential.   view more (2008-10-13)

Burnham Researchers Turn Cancer Friend into Cancer Foe
Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer.   view more (2008-10-08)

Nanoscopic screening process to speed drug discovery
Researchers at Wake Forest University are using nanotechnology to search for new cancer-fighting drugs through a process that could be up to 10,000 times faster than current methods.   view more (2008-10-07)
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