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Study reveals why certain drug combinations backfire
Combination drug therapy has become a staple for treating many infections. For instance, doctors treat extensively drug resistant forms of tuberculosis with one drug that breaks down the pathogen's protective barriers and opens the door for another to deliver the deathblow.   view more (2009-11-16)

Drug industry, nonprofits join forces to fight world's neglected diseases
Drug companies and nonprofit organizations are joining forces to develop new drugs and vaccines to target so-called "neglected" diseases that claim millions of lives in the developing world each year.   view more (2009-11-12)

Despite some benefit, drug ads can be harmful to your health
While the debate over prescription drug advertising persists, a new study released online in the American Journal of Public Health offers guidelines for improving drug ads in order to minimize potential harm and maximize benefits.   view more (2009-11-12)

Right first time: Pioneering new methods of drug manufacture
Engineers at the University of Leeds have developed a simple technology which can be used in existing chemical reactors to ensure "right first time" drug crystal formation.   view more (2009-11-11)

Forget all about it: Traumatic memories can be erased
It is well known that fear memories are permanent. However, a recent paper in Science, evaluated by three Faculty Members for F1000, reports an extraordinary finding that supports the use of a drug to control recollections of traumatic incidents.   view more (2009-11-10)

FDA approved leukemia drugs shows promise in ovarian cancer cells
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA's Jonsson Comprehensive Cancer Center found.   view more (2009-11-10)

1930s drug slows tumor growth
Drugs sometimes have beneficial side effects. A glaucoma treatment causes luscious eyelashes. A blood pressure drug also aids those with a rare genetic disease.   view more (2009-11-09)

Developmental drug may help bone fractures heal after radiation exposure
A drug currently under development by the University of Pittsburgh School of Medicine may help bone fractures heal more quickly after radiation exposure, according to a study by Pitt researchers.   view more (2009-11-03)

Duke develops nano-scale drug delivery for chemotherapy
Going smaller could bring better results, especially when it comes to cancer-fighting drugs.   view more (2009-11-02)

Optimized inhaler mouthpiece design allows for more effective drug delivery
Researchers have developed an optimized mouthpiece design to aid efficient drug delivery to the lungs by reducing the amount of medication wasted as it passes through the mouthpiece of an aerosol inhaler.   view more (2009-10-22)

Scientists develop novel method to generate functional hepatocytes for drug testing
Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell (iPSC) technology.   view more (2009-10-21)

Substance abuse diagnostic test for teens can also predict high risk sexual behavior
Alcohol and drug use are known contributors to adolescents engaging in dangerous sexual activity; leading to substantial health risks such as unwanted pregnancies, sexually transmitted illnesses, drug overdoses and alcohol poisonings.   view more (2009-10-19)

Metals could forge new cancer drug
Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds.   view more (2009-10-19)

UK incidence of children living with substance-misusing parents considerably underestimated
Current figures underestimate the number of children who may be at risk of harm from parental substance use. Researchers writing in the open access journal BMC Public Health have generated new estimates using five national surveys which include measures of binge, hazardous and dependent drinking, illicit drug use and mental health.   view more (2009-10-08)

New Chemo Cocktail Blocks Breast Cancer Like a Fence
Think of a protective fence that blocks the neighbor's dog from charging into your backyard. The body, too, has fences -- physical and biochemical barriers that keep cells in their place.   view more (2009-10-07)

Teen attitudes toward smoking linked to likelihood of drinking and using drugs
New research by Weill Cornell Medical College researchers looks at the specific ways parents and peers influence teenagers to smoke, drink and use marijuana in combination.   view more (2009-10-01)

New blood-thinning drug safer than rat poison
In an article reviewed by F1000 Medicine Faculty Members Robert Ruff, Brian Olshansky and Luis Ruilope, the blood-thinner dabigatran is shown to protect against stroke, blood clotting and major bleeding as effectively as warfarin, but with fewer side effects.   view more (2009-09-30)

New Paper from Internists Calls for Increased Role for FDA
A new policy paper that calls for broader authority and increased funding for the Food and Drug Administration (FDA) was released today by the American College of Physicians (ACP). Improving FDA Regulation of Prescription Drugs offers a half-dozen recommendations about how to improve the agency's ability to approve and monitor new drugs.    view more (2009-09-25)

Nanoparticle-based battlefield pain treatment moves step closer
University of Michigan scientists have developed a combination drug that promises a safer, more precise way for medics and fellow soldiers in battle situations to give a fallen soldier both morphine and a drug that limits morphine's dangerous side effects.   view more (2009-09-25)

Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease.   view more (2009-09-24)
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