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Study: Delaying evolution of drug resistance in malaria parasite possible
There's no magic bullet for wiping out malaria, but a new study offers strong support for a method that effectively delays the evolution of drug resistance in malaria parasites, a University of Florida researcher says.   view more (2008-09-05)

Safety of antithrombotic treatment in acute coronary syndromes
The management of acute coronary syndromes (with or without ST segment elevation) requires the use of anticoagulants, antiplatelet agents (aspirin, clopidogrel and/or glycoprotein (GP) IIb/IIIa inhibitors), beta-blockers, thrombolytics in some cases, and revascularization / reperfusion.   view more (2008-09-03)

College freshmen: pain killers and stimulants less risky than cocaine; more risky than marijuana
First year college students believe that occasional nonmedical use of prescription pain killers and stimulants is less risky than cocaine, but more risky than marijuana or consuming five or more alcoholic beverages every weekend.   view more (2008-09-03)

Post-marketing studies finding adverse events in drugs used in children
The Food and Drug Administration Modernization Act (FDAMA, 1997), designed to stimulate more drug safety studies in children, has resulted in more than 130 label changes since its inception nearly six years ago, according to researchers at Duke Children's Hospital.   view more (2008-09-02)

Class of diabetes drugs carries significant cardiovascular risks
A class of oral drugs used to treat type 2 diabetes may make heart failure worse, according to an editorial published online in Heart Wednesday by two Wake Forest University School of Medicine faculty members.   view more (2008-08-29)

Cell removal technique could lead to cheaper drugs
Researchers at the University of Edinburgh have pioneered a simple way to remove dead cells from cell cultures used to make protein-based drugs, which are increasingly prescribed to treat a range of illnesses.   view more (2008-08-27)

ABC-transporters expressed on endothelial cell membranes efflux anti-HIV drugs
Researchers at Tulane University Medical Center in New Orleans (USA) have discovered that drug-efflux pumps, belonging to the ATP-binding cassette (ABC) transporter family, are constitutively expressed on vascular endothelial cells.   view more (2008-08-27)

Anti-psychotic drug use in the elderly increases despite drug safety warnings
Three regulatory warnings of serious adverse events slowed the growth of use of atypical antipsychotic drugs among elderly patients with dementia, but they did not reduce the overall prescription rate of these drugs.   view more (2008-08-26)

Looking beyond the drug receptor for clues to drug effectiveness
Antipsychotic drugs that are widely used to treat schizophrenia and other problems may not work as scientists have assumed, according to findings from Duke University Medical Center researchers that could lead to changes in how these drugs are developed and prescribed.   view more (2008-08-26)

Chips are down as Manchester makes protein scanning breakthrough
Scientists at The University of Manchester have developed a new and fast method for making biological 'chips' - technology that could lead to quick testing for serious diseases, fast detection of MRSA infections and rapid discovery of new drugs.   view more (2008-08-25)

MIT zeroes in on Alzheimer's structures
MIT engineers report a new approach to identifying protein structures key to Alzheimer's disease, an important step toward the development of new drugs that could prevent such structures from forming.   view more (2008-08-22)

Drugs to inhibit blood vessel growth show promise in rat model of deadly brain tumor
In a landmark study, Medical College of Wisconsin researchers in Milwaukee report that drugs used to inhibit a specific fatty acid in rat brains with glioblastoma-like tumors not only reduced new blood vessel growth and tumor size dramatically, but also prolonged survival. The study is the featured... view more (2008-08-22)

Guideline: Surgery may be considered for extreme face pain
A new guideline developed by the American Academy of Neurology finds surgery may be considered for people who suffer from extreme, electric shock-like pain in their face and do not respond well to drugs.   view more (2008-08-21)

New test to diagnose osteoarthritis early
A newly developed medical imaging technology may provide doctors with a long-awaited test for early diagnosis of osteoarthritis (OA), scientists from New York reported today at the 236th National Meeting of the American Chemical Society.   view more (2008-08-21)

Antidepressants may impair driving ability, new research finds
People taking prescription antidepressants appear to drive worse than people who aren't taking such drugs, and depressed people on antidepressants have even more trouble concentrating and reacting behind the wheel.   view more (2008-08-18)

Rheb's role in cancer
Two independent papers in the August 15th issue of G&D identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target.   view more (2008-08-15)

How chemo kills tumours: research to reduce side effects
Dr Stephen Taylor and Karen Gascoigne at the University's Faculty of Life Sciences have taken a new systematic approach to studying anti-mitotic drugs, which are used extensively for breast or ovarian cancer in the UK.   view more (2008-08-07)

Toxic drugs, toxic system: Sociologist predicts drug disasters
Americans are likely to be exposed to unacceptable side effects of FDA-approved drugs such as Vioxx in the future because of fatal flaws in the way new drugs are tested and marketed, according to research to be presented today at the annual meeting of the American Sociological Association (ASA).   view more (2008-08-04)

New Guidelines for Treating Rheumatoid Arthritis
Proven combinations of medicines and the introduction of new anti-arthritis drugs have significantly improved the treatment of rheumatoid arthritis (RA), according to guidelines issued by the American College of Rheumatology and co-authored by physicians at the University of Alabama at Birmingham... view more (2008-07-23)

Drug lowers body's 'set point' to control hyperparathyroidism in dialysis patients
A medication called cinacalcet-an important part of treatment to control high levels of parathyroid hormone (PTH) in patients receiving dialysis for end-stage renal disease (ESRD)-works by resetting the balance between calcium and PTH levels, according to a study in the November Journal of the... view more (2008-07-17)

Novel approach may protect against heart attack injury
Researchers at The Children's Hospital of Philadelphia have manipulated cell activity that occurs during the interruption of blood flow to strongly protect heart tissue in animal studies.   view more (2008-07-11)

Fruit fly gene study could yield new flu treatments
As they design new drugs to fight off influenza, scientists may not need to attack the virus directly. Instead, they may be able to stave off infection by targeting one of more than 100 proteins inside host cells on which the virus depends.   view more (2008-07-10)

Depression after stroke: a neglected problem
People who have had a stroke and the people who are close to them need more support in order to manage the consequences of stroke.   view more (2008-07-10)

Some drugs increase risk of falling: UNC researchers
Researchers at the University of North Carolina at Chapel Hill have created a list of prescription drugs that increase the risk of falling for patients aged 65 and older who take four or more medications on a regular basis.   view more (2008-07-10)

Some antidepressants associated with gastrointestinal bleeding
A class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) appear to be associated with bleeding in the upper gastrointestinal tract.   view more (2008-07-08)
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