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Potential new target for cancer found
By bypassing a well-known gene implicated in almost one-third of all cancers and instead focusing on the protein activated by the gene, Duke University Medical Center researchers believe they may have found a new target for anti-cancer drugs.   view more (2007-07-16)

Evidence underlying repeated courses of steroids for preterm birth is unsound
Researchers in this week's BMJ question whether giving repeated courses of steroid drugs to mothers at risk of preterm delivery is based on sound evidence.   view more (2007-07-13)

St. Jude study shows temporary improvement of tumor blood flow can improve chemotherapy
A treatment for neuroblastoma that lands a one-two punch works best when the second punch is timed to take maximum advantage of the first one, according to results of studies at St. Jude Children's Research Hospital.   view more (2007-07-12)

Is milk thistle effective in cancer treatment?
Milk thistle extract, an herbal remedy since the times of the ancient Greeks and Romans, is today one of the most popular herbal supplements, with U.S. retail sales of nearly nine million dollars.   view more (2007-07-11)

Young adults not at risk of suicidal behavior from antidepressants
Antidepressants lower the risk of suicide attempt in adults with depression, according to a study published in the July issue of the American Journal of Psychiatry.   view more (2007-07-09)

A genetic factor predicts prognosis in brain tumor patients
PLoS ONE has just published a study which defines a gene locus on chromosome 1 that predicts prognosis of brain tumor patients and may even set the basis for the development of more efficient drugs to combat brain cancer.   view more (2007-06-28)

Drugs used to fight cancer-related bone problems boost odds of jaw- or face-bone disease
Treatment with intravenous bisphosphonates - drugs used to reduce harm done to bones by cancer or cancer therapy - increases the risk of jaw or facial bone disease or infection, a large-scale comparative study by researchers at the University of Texas Medical Branch at Galveston (UTMB) has found.   view more (2007-06-27)

Nanoparticles hitchhike on red blood cells: a potential new method for drug delivery
Researchers at the University of California, Santa Barbara have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles.   view more (2007-06-27)

Modified mushrooms may yield human drugs
Mushrooms might serve as biofactories for the production of various beneficial human drugs, according to plant pathologists who have inserted new genes into mushrooms.   view more (2007-06-25)

Questions over drugs to prevent heart complications during surgery
Globally, about 100 million adults have non-cardiac surgery (ie. on any part of the body other than the heart) each year. Around 1% are at risk of cardiac complications, such as heart attacks and strokes, and about one in four will die each year.   view more (2007-06-25)

K-State researcher examining why common anti-inflammatory drugs harm intestines
New versions of drugs like buffered aspirin and Vioxx could produce fewer harmful side effects thanks to research being done at Kansas State University's College of Veterinary Medicine.   view more (2007-06-25)

Hepatitis B drug can compromise HIV treatment
Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal.   view more (2007-06-21)

1 in 100 11-year-olds use drugs to enhance performance in sport
More than one per cent of eleven year olds admit using performance enhancing drugs to do better in sports reports a study published online ahead of print in the British Journal of Sports Medicine.   view more (2007-06-20)

Personal drug selection: Problem-based learning in pharmacology
Irrational use of medicines is a major problem all over the world. The World Health Organization (WHO) and many other bodies are concentrating on improving the use of medicines.   view more (2007-06-13)

U-M researchers discover gene switched off in cancer can be turned on
A gene implicated in the development of cancer cells can be switched on using drugs, report researchers from the University of Michigan Comprehensive Cancer Center.   view more (2007-06-12)

Study suggests newer breast cancer drug may protect heart
By uncovering how one breast cancer drug protects the heart and another does not, Duke University Medical Center researchers believe they may have opened up a new way to screen drugs for possible heart-related side effects and to develop new drugs.   view more (2007-06-11)

UCLA researchers develop new nanomaterials to deliver anti-cancer drugs to cells
Researchers at UCLA have successfully manipulated nanomaterials to create a new drug-delivery system that promises to solve the challenge of the poor water solubility of today's most promising anticancer drugs and thereby increase their effectiveness.   view more (2007-06-08)

Hormone helps mice 'hibernate,' survive starvation
A key hormone enables starving mice to alter their metabolism and "hibernate" to conserve energy, revealing a novel molecular target for drugs to treat human obesity and metabolic disorders, UT Southwestern Medical Center researchers have found.   view more (2007-06-06)

Genomic signatures identify targeted therapies for lung cancer
Any number of things can go wrong in the cells of the body to cause cancer -- and clinicians can't tell by just looking at a tumor what exactly triggered the once normal cells to turn cancerous.   view more (2007-06-04)

Ireland Cancer Center researcher lays out benefits of aspirin to prevent colon cancer
A colon cancer researcher at the Ireland Cancer Center of University Hospitals Case Medical Center (UHCMC) has laid out the roadmap for how medical science should employ aspirin and new aspirin-like drugs for use in preventing colon cancer in certain high-risk individuals.   view more (2007-05-24)

Certain combination therapy found more effective for treating malaria in African children
Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA, a theme issue on malaria.   view more (2007-05-23)

Drug eluting nanostructured coatings enable targeted drug therapy for orthopedic patients
Drug delivery systems have progressed from the teaspoon to time-release capsules to drug-eluting stents. Nanotechnology promises yet another advance by delivering therapeutic agents at desired rates exactly where needed in the body.   view more (2007-05-21)

Inherited genes linked to toxicity of leukemia therapy
Investigators at St. Jude Children's Research Hospital have discovered inherited variations in certain genes that make children with acute lymphoblastic leukemia (ALL) susceptible to the toxic side effects caused by chemotherapy medications.   view more (2007-05-14)

Comparison of patients' access to new and better cancer drugs reveals inequalities between countries
Patients around the world face stark inequalities in access to cancer treatment, according to a report published today (Thursday 10 May) in the cancer journal, Annals of Oncology [1].   view more (2007-05-10)

Effectiveness of first renin inhibitor drug for treating hypertension is limited
Hypertension is a serious condition affecting millions. Currently there are seven classes of drugs used to reduce blood pressure.   view more (2007-05-10)
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