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Looking beyond the drug receptor for clues to drug effectiveness
Antipsychotic drugs that are widely used to treat schizophrenia and other problems may not work as scientists have assumed, according to findings from Duke University Medical Center researchers that could lead to changes in how these drugs are developed and prescribed.   view more (2008-08-26)

Chips are down as Manchester makes protein scanning breakthrough
Scientists at The University of Manchester have developed a new and fast method for making biological 'chips' - technology that could lead to quick testing for serious diseases, fast detection of MRSA infections and rapid discovery of new drugs.   view more (2008-08-25)

MIT zeroes in on Alzheimer's structures
MIT engineers report a new approach to identifying protein structures key to Alzheimer's disease, an important step toward the development of new drugs that could prevent such structures from forming.   view more (2008-08-22)

Drugs to inhibit blood vessel growth show promise in rat model of deadly brain tumor
In a landmark study, Medical College of Wisconsin researchers in Milwaukee report that drugs used to inhibit a specific fatty acid in rat brains with glioblastoma-like tumors not only reduced new blood vessel growth and tumor size dramatically, but also prolonged survival. The study is the featured... view more (2008-08-22)

Guideline: Surgery may be considered for extreme face pain
A new guideline developed by the American Academy of Neurology finds surgery may be considered for people who suffer from extreme, electric shock-like pain in their face and do not respond well to drugs.   view more (2008-08-21)

New test to diagnose osteoarthritis early
A newly developed medical imaging technology may provide doctors with a long-awaited test for early diagnosis of osteoarthritis (OA), scientists from New York reported today at the 236th National Meeting of the American Chemical Society.   view more (2008-08-21)

Antidepressants may impair driving ability, new research finds
People taking prescription antidepressants appear to drive worse than people who aren't taking such drugs, and depressed people on antidepressants have even more trouble concentrating and reacting behind the wheel.   view more (2008-08-18)

Rheb's role in cancer
Two independent papers in the August 15th issue of G&D identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target.   view more (2008-08-15)

How chemo kills tumours: research to reduce side effects
Dr Stephen Taylor and Karen Gascoigne at the University's Faculty of Life Sciences have taken a new systematic approach to studying anti-mitotic drugs, which are used extensively for breast or ovarian cancer in the UK.   view more (2008-08-07)

Toxic drugs, toxic system: Sociologist predicts drug disasters
Americans are likely to be exposed to unacceptable side effects of FDA-approved drugs such as Vioxx in the future because of fatal flaws in the way new drugs are tested and marketed, according to research to be presented today at the annual meeting of the American Sociological Association (ASA).   view more (2008-08-04)

New Guidelines for Treating Rheumatoid Arthritis
Proven combinations of medicines and the introduction of new anti-arthritis drugs have significantly improved the treatment of rheumatoid arthritis (RA), according to guidelines issued by the American College of Rheumatology and co-authored by physicians at the University of Alabama at Birmingham... view more (2008-07-23)

Drug lowers body's 'set point' to control hyperparathyroidism in dialysis patients
A medication called cinacalcet-an important part of treatment to control high levels of parathyroid hormone (PTH) in patients receiving dialysis for end-stage renal disease (ESRD)-works by resetting the balance between calcium and PTH levels, according to a study in the November Journal of the... view more (2008-07-17)

Novel approach may protect against heart attack injury
Researchers at The Children's Hospital of Philadelphia have manipulated cell activity that occurs during the interruption of blood flow to strongly protect heart tissue in animal studies.   view more (2008-07-11)

Fruit fly gene study could yield new flu treatments
As they design new drugs to fight off influenza, scientists may not need to attack the virus directly. Instead, they may be able to stave off infection by targeting one of more than 100 proteins inside host cells on which the virus depends.   view more (2008-07-10)

Depression after stroke: a neglected problem
People who have had a stroke and the people who are close to them need more support in order to manage the consequences of stroke.   view more (2008-07-10)

Some drugs increase risk of falling: UNC researchers
Researchers at the University of North Carolina at Chapel Hill have created a list of prescription drugs that increase the risk of falling for patients aged 65 and older who take four or more medications on a regular basis.   view more (2008-07-10)

Some antidepressants associated with gastrointestinal bleeding
A class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) appear to be associated with bleeding in the upper gastrointestinal tract.   view more (2008-07-08)

Asthma risk increases in children treated for HIV
Children whose immune systems rebound after treatment with potent anti-viral drugs for HIV infection face an increased risk of developing asthma, said a federally funded consortium of researchers led by those from Baylor College of Medicine in a report that appears online in the Journal of Allergy... view more (2008-07-02)

'Multi-target' immune therapy improves outcomes of severe lupus nephritis
A new treatment using a combination of drugs targeting different parts of the immune system improves the recovery rate for patients with severe lupus involving the kidneys, according to a report in the October Journal of the American Society of Nephrology (JASN).   view more (2008-07-02)

Best treatment for MS may depend on disease subtype
Animal studies by University of Michigan scientists suggest that people who experience the same clinical signs of multiple sclerosis (MS) may have different forms of the disease that require different kinds of treatment.   view more (2008-07-02)

Should doctors be 'selling' drugs for the pharmaceutical industry?
Are senior doctors who help drug companies sell their drugs independent experts or just drug representatives in disguise, asks Ray Moynihan from the University of Newcastle in Australia, in this week's BMJ.   view more (2008-06-20)

Computers as safe as medical experts for prescribing blood thinning drugs
The largest ever study into the administration of blood thinning drugs, principally Warfarin, has concluded that dosages calculated by computer are at least as safe and reliable as those provided by expert medical professionals.   view more (2008-06-19)

Indiana U scientists uncover potential key to better drugs to fight toxoplasmosis parasite
Discoveries by Indiana University School of Medicine scientists have opened a promising door to new drugs for toxoplasmosis and other parasites that now can evade treatments by turning dormant in the body.   view more (2008-06-19)

Fair and adequate reimbursement is vital to developing life-saving medical treatments
Reimbursement of molecular imaging and therapies-leading to the early detection and diagnosis of many life-threatening diseases-remains an urgent and critical need as consumers face ever-increasing healthcare costs.   view more (2008-06-18)

Some patients may not need insulin for long-term control of type 2 diabetes
Some patients with type 2 diabetes can control their disease for years yet avoid insulin injections by using multiple classes of oral diabetic medications, a new study found.   view more (2008-06-16)
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