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Prenatal drug exposure linked to sleep problems in children
In the first study across time into late childhood of the effects of prenatal drug exposure on sleep, prenatal drug exposure is associated with greater sleep problems in children.   view more (2008-06-10)

Synthetic molecules hold promise for new family of anti-cancer drugs
Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue.   view more (2008-06-05)

Enzyme may hold key to improved targeting of cancer-fighting drugs
A critical enzyme used to prepare a powerful cancer-killing agent may be able to help drug makers better target the cells the natural product attacks, according to findings published in the May 23 edition of the Journal of Biological Chemistry.   view more (2008-05-30)

Short-term use of antipsychotics in older adults with dementia linked to serious adverse events
Older adults with dementia who receive short-term courses of antipsychotic medications are more likely to be hospitalized or die than those who do not take the drugs, according to a report in the May 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2008-05-27)

A trial of removing food additives should be considered for hyperactive children
A properly supervised trial eliminating colours and preservatives from the diet of hyperactive children should considered a part of the standard treatment, says an editorial in this week's BMJ.   view more (2008-05-23)

Anti-rejection drug may increase risk of diabetes after kidney transplant
For patients undergoing kidney transplantation, treatment with the anti-rejection drug sirolimus may lead to an increased risk of diabetes, reports a study in the July Journal of the American Society of Nephrology (JASN).   view more (2008-05-23)

Tuberculosis not the only risk from new immunological drugs
A new survey cautions physicians that drugs commonly prescribed for patients suffering from immunological disorders such as rheumatoid arthritis and inflammatory bowel disease may carry risks of serious infections other than the known risk of tuberculosis.   view more (2008-05-21)

New Mount Sinai research tracks effects of addictive drugs on brain
Mount Sinai researchers may have unlocked the key to better understanding the effect addictive drugs have on the human brain.   view more (2008-05-16)

Compound has potential for new class of AIDS drugs
Researchers have developed what they believe is the first new mechanism in nearly 20 years for inhibiting a common target used to treat all HIV patients, which could eventually lead to a new class of AIDS drugs.   view more (2008-05-15)

Young people are intentionally taking drink and drugs for better sex
Teenagers and young adults across Europe drink and take drugs as part of deliberate sexual strategies. Findings published today in BioMed Central's open access journal, BMC Public Health, reveal that a third of 16-35 year old males and a quarter of females surveyed are drinking alcohol to increase... view more (2008-05-09)

When statins aren't enough: New trial drug points to better management of coronary heart disease
Despite widespread use of cholesterol-lowering drugs, a significant number of cardiac patients continue to suffer heart attacks and stroke. Researchers theorize that high levels of an enzyme found in coronary plaques may be to blame, by making plaques more likely to rupture and block blood flow.   view more (2008-05-09)

Commonly used medications associated with impaired physical function in older adults
Older adults who take drugs designed to block the neurotransmitter acetylcholine - including common medications for incontinence, high blood pressure and allergies - are more likely to be dependent in one or more activities of daily living and to walk slower, according to new findings from... view more (2008-05-05)

Getting wise to the influenza virus' tricks
Influenza is currently a grave concern for governments and health organisations around the world. The worry is the potential for highly virulent bird flu strains, such as H5N1, to develop the ability to infect humans easily. New drugs and vaccines to halt the spread of the virus are badly needed.   view more (2008-05-05)

Dual treatment of incontinence and dementia associated with functional decline
Older nursing home residents who took medications for dementia and incontinence at the same time had a 50 percent faster decline in function than those who were being treated only for dementia, according to a study from researchers at Wake Forest University School of Medicine and colleagues.   view more (2008-05-01)

Zebrafish may help solve ringing in vets' ears
Ernest Moore, an audiologist and cell biologist at Northwestern University, developed tinnitus -- a chronic ringing and whooshing sound in his ears -- twenty years ago after serving in the U.S. Army reserves medical corps.   view more (2008-05-01)

UIC scientists discover how some bacteria survive antibiotics
Researchers at the University of Illinois at Chicago have discovered how some bacteria can survive antibiotic treatment by turning on resistance mechanisms when exposed to the drugs. The findings, published in the April 24 issue of the journal Molecular Cell, could lead to more effective... view more (2008-05-01)

USC School of Dentistry researchers uncover link between osteoporosis drugs and jaw infection
A group of University of Southern California School of Dentistry researchers says it has identified the slimy culprits killing the jawbones of some people taking drugs that treat osteoporosis.   view more (2008-04-30)

Researchers discover molecular basis of a form of muscular dystrophy
A team of French and German researchers report in the May 2008 print issue of The FASEB Journal (http://www.fasebj.org) that people with limb-girdle muscular dystrophy are missing a protein called c-FLIP, which the body uses to prevent the loss of muscle tissue.   view more (2008-04-30)

Scientists discover the double life of proteins
Scientists at The Australian National University are a step closer to understanding the rare Hartnup disorder after discovering a surprising link between blood pressure regulation and nutrition that could also help to shed light on intestinal and kidney function.   view more (2008-04-30)

Gastric juice for diagnosis of H. pylori infection in patients on proton pump inhibitors
This study determined the efficiency of a gastric juice PCR test for the detection of H. pylori infection in patients receiving PPI therapy and compared it with histology and gastric biopsy PCR.   view more (2008-04-30)

Investigators unveil new drug discovery tool for Alzheimer's disease
An article published in the April issue of the Journal of Alzheimer's Disease presents a detailed characterization of a new drug discovery tool for Alzheimer's disease.   view more (2008-04-29)

Opening a channel for salt retention
A research team has developed the first small molecule that can reversibly activate a key protein involved in balancing sodium levels, paving the way for drugs that can treat low blood pressure and related conditions.   view more (2008-04-28)

Gene therapy reduces cocaine use in rats
Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have shown that increasing the brain level of receptors for dopamine, a pleasure-related chemical, can reduce use of cocaine by 75 percent in rats trained to self-administer it.   view more (2008-04-16)

Brain study may lead to improved epilepsy treatments
Using a rodent model of epilepsy, researchers found one of the body's own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain.   view more (2008-04-15)

No 'convincing evidence' that glitazones work better than older diabetes drugs
There is no convincing evidence that the newer class of diabetes drugs, known as glitazones, offer real advantages over other diabetes drugs, when used on their own, concludes the Drug and Therapeutics Bulletin (DTB).   view more (2008-04-10)
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