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Targeting gut bugs could revolutionize future drugs, say researcher
Revolutionary new ways to tackle certain diseases could be provided by creating drugs which change the bugs in people's guts, according to a Perspective article published today in the journal Nature Reviews Drug Discovery.   view more (2008-02-04)

Building stronger bones, 1 stem cell at a time
Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.   view more (2008-01-25)

Genetic difference predicts antidepressant response
Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant drugs.   view more (2008-01-24)

Experimental procedure induces tolerance to mismatched kidney transplants
Four of five patients participating in a trial of an experimental protocol designed to induce immune tolerance to HLA-mismatched kidney transplants have been able to discontinue immunosuppressive drugs.   view more (2008-01-24)

Stanford study finds transplant patient thrives 2 years after stopping immunosuppressive drugs
Luck smiled on Larry Kowalski when his brother agreed to donate a kidney Kowalski needed to live. He was even luckier that his brother's kidney was such a good match.   view more (2008-01-24)

Scientists use nanomaterials to localize and control drug delivery
Using nanotechnology, scientists from UCLA and Northwestern University have developed a localized and controlled drug delivery method that is invisible to the immune system, a discovery that could provide newer and more effective treatments for cancer and other diseases.   view more (2008-01-23)

Further breakthroughs for breast cancer patients
Researchers at the Tenovus Centre for Cancer Research at Cardiff University have made a breakthrough in breast cancer treatment that could help save the lives of women who become resistant to breast cancer drugs such as tamoxifen.   view more (2008-01-21)

A new view of drugs used to treat rheumatoid arthritis
Powerful drugs used to treat patients with rheumatoid arthritis have a profound, previously unrecognized effect on the immune system, breaking up molecular "training camps" for rogue cells that play an increasingly recognized role in autoimmune diseases like rheumatoid arthritis and lupus.   view more (2008-01-21)

Risk of falling is overlooked as the major cause of fractures in the elderly
An elderly person's risk of falling is too often overlooked when trying to prevent them from getting serious fractures, for instance of the hip or wrist, according to an article published in this week's BMJ.   view more (2008-01-18)

Value of drugs for pre-osteoporosis exaggerated
A series of recent scientific publications have exaggerated the benefits and underplayed the harms of drugs to treat pre-osteoporosis or "osteopenia" potentially encouraging treatment in millions of low risk women, warn experts in this week's BMJ.   view more (2008-01-18)

Altering brain's lipid metabolism reduces Alzheimer's plaques in mice
Increasing levels of a protein that helps the brain use cholesterol may slow the development of Alzheimer's disease changes in the brain.   view more (2008-01-18)

Diet and lifestyle critical to recovery, says study
Diet and lifestyle may play a much more significant role in a person's ability to respond favourably to certain drugs, including some cancer therapies, than previously understood, say scientists.   view more (2008-01-18)

Selective reporting of antidepressant trials exaggerates drug effectiveness
Selective publication in reporting results of antidepressant trials exaggerates the effectiveness of the drugs, according to a report in the January 17 issue of the New England Journal of Medicine.   view more (2008-01-17)

Weight gain induced by antipsychotic drugs can be avoided
A research team from Université Laval's Faculty of Medicine and Robert-Giffard Hospital has demonstrated that weight gain induced by the use of antipsychotic drugs-which in extreme cases can be as high as 30 kilos in only one month-can be avoided through a specially designed weight control... view more (2008-01-17)

Hormonal dietary supplements might promote prostate cancer progression
Hormonal components in over-the-counter dietary supplements may promote the progression of prostate cancer and decrease the effectiveness of anti-cancer drugs, researchers at UT Southwestern Medical Center have discovered.    view more (2008-01-16)

Popular osteoporosis drugs triple risk of bone necrosis
A University of British Columbia and Vancouver Coastal Health Research Institute study has found that a popular class of osteoporosis drugs nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain.   view more (2008-01-16)

Existing antiretroviral drugs may thwart vaginal HIV transmission, researchers report
Prescription drugs now used to treat human immunodeficiency virus infection in adults may prevent the vaginal transmission of HIV, researchers at UT Southwestern Medical Center have found.   view more (2008-01-15)

2 different neural pathways regulate loss and regain of consciousness during general anesthesia
University of Pennsylvania School of Medicine researchers have answered long-running questions about the way that anesthetics act on the body, by showing that the cellular pathway for emerging from anesthesia is different from the one that drugs take to put patients to sleep during operations.   view more (2008-01-14)

Memantine and Alzheimer's disease
In a study published this month in the Journal of Alzheimer's Disease, researchers from the University of Aberdeen report that the drug memantine, used for the treatment of Alzheimer's disease and praised as "the first and only representative of a new class of Alzheimer drugs" works in... view more (2008-01-11)

Device prevents potential errors in children's medications
A device designed to eliminate mistakes made while mixing compounds at a hospital pharmacy was 100 percent accurate in identifying the proper formulations of seven intravenous drugs.   view more (2008-01-09)

Oral osteoporosis meds appear to reduce the risk of jaw degradation
Athanasios Zavras began receiving messages from distraught patients in 2005 after case reports linked oral osteoporosis meds to bone death in the jaw.   view more (2008-01-03)

Some antipsychotic drugs may be missing their mark
Drugs that treat depression, schizophrenia and other psychotic conditions and that target a particular protein on brain cells might not be triggering the most appropriate response in those cells, new research suggests.   view more (2008-01-02)

New clinical trial results show how personalized medicine will alter treatment of genetic disorders
One of the nation's pre-eminent genetic researchers, Eric Hoffman, PhD, of Children's Research Institute at Children's National Medical Center, predicts that in relatively short order, medicine's next innovation--individualized molecular therapies--will have the unprecedented ability to treat... view more (2007-12-27)

Cancer stem cells: know thine enemy
Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer.   view more (2007-12-26)

Results promising for computational quantum chemical methods for drug development
New research, led by a Virginia Tech chemist, may someday help natural-products chemists decrease by years the amount of time it takes for the development of certain types of medicinal drugs.   view more (2007-12-21)
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