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Intensive care quality of sleep improved by new drug, reports study
A new sedative drug has been shown to improve the sleep quality and comfort levels of intensive care patients, compared to the most commonly-used medication, according to research published today in the journal JAMA.   view more (2007-12-13)

Blood Pressure Drug Telmisartan Shows Powerful Activity Against Stroke
Telmisartan, a drug widely used to help control blood pressure, may have uniquely potent activity in preventing stroke, according to a new study conducted in an animal model.   view more (2007-12-13)

Possible genetic predictor for response to lithium augmentation in depressed patients
As in most fields of medicine, psychiatry researchers are working to identify specific types of patients, through their individual genetic variations, that may better benefit from particular drugs or combinations of drugs than other patients.   view more (2007-12-07)

New chimeric mouse model for human liver diseases, drug testing
Cells cultured in the lab are like a fish out of water. Often, their behavior does not reflect their biological function within an entire organ or organism, which, for example, turns studying human liver cells into a big challenge.   view more (2007-12-04)

Club drugs inflict damage similar to traumatic brain injury
What do suffering a traumatic brain injury and using club drugs have in common"? University of Florida researchers say both may trigger a similar chemical chain reaction in the brain, leading to cell death, memory loss and potentially irreversible brain damage.    view more (2007-11-30)

Europe to tackle brain disorder research by linking industry, academia
Attempts to cure brain-related disorders have proved less successful than therapies for other major conditions such as heart cancer, even though just as many people suffer from them.   view more (2007-11-28)

A new computational technique predicts side-effects of a major cancer drug
Researchers at the University of California San Diego have developed a novel computer technique to search for the side effects of major pharmaceuticals.   view more (2007-11-28)

Drugs may not delay onset of dementia; and more
Researchers have examined the evidence in favour of giving people considered to be close to developing dementia the drugs that are most commonly used to treat the condition itself.   view more (2007-11-27)

For treating malaria, less drugs may be best drugs
The current dosage of drugs used in treating malaria may be helping the parasites become resistant to the drugs faster, without improving the long-term outcome in patients.   view more (2007-11-27)

FDA petition would protect public from dangerous drugs
In a petition filed today with the U.S. Food and Drug Administration, an international coalition of scientists and doctors seeks to compel the agency to stem the flood of dangerous drugs reaching American consumers by mandating the use of scientifically superior non-animal testing methods when... view more (2007-11-15)

HIV drug resistance risk in mothers reduced by combination of common drugs
New research from the University of Alabama at Birmingham (UAB) shows that adding a single dose of two common anti-HIV drugs can prevent HIV-positive pregnant women from developing resistance to an entire class of drugs, potentially improving future treatment options.   view more (2007-11-12)

New drug combination shows promise for African sleeping sickness
A small clinical trial in Uganda, conducted within a long-established Médecins Sans Frontières (MSF) treatment program for African sleeping sickness, has found that a new combination treatment using the drugs nifurtimox and eflornithine holds promise and deserves further evaluation.   view more (2007-11-07)

Survey identifies characteristics of teens who smoke marijuana but not tobacco
A Swiss study suggests that teens who use only cannabis appear to function better than those who also use tobacco, and are more socially driven and have no more psychosocial problems than those who abstain from both substances.   view more (2007-11-06)

Common drug for stopping preterm labor may be harmful for babies
A drug commonly used to halt premature labor may be associated with brain damage and intestinal issues in premature babies, according to a new analysis of studies on the issue published today in American Journal of Obstetrics and Gynecology.   view more (2007-11-02)

Anti-hypertensive drugs may help prevent and treat Alzheimer's disease
A new study has identified commonly prescribed drugs for the treatment of hypertension may be capable of preventing Alzheimer�s disease and cognitive deterioration.   view more (2007-10-26)

Study shows blood markers can help choose best dose for antiangiogenic drugs
Scientists at Sunnybrook have new information that may help to improve the use of anti-cancer drugs designed to block the growth of new blood vessels in tumors, a process called angiogenesis that is critical to tumor growth.   view more (2007-10-26)

Nanoballs deliver drugs
Dutch researcher Cristianne Rijcken has developed a new type of biodegradable nanoparticle. The spherical structures can encapsulate various fat-soluble medicines, which makes it easier to target tumour tissue.   view more (2007-10-25)

A new chemotherapeutic target for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation.   view more (2007-10-25)

XDR TB in South Africa traced to lack of drug susceptibility testing
In South Africa, the 2001 implementation of the World Health Organization's anti-tuberculosis program may have inadvertently helped to create a new strain of extensively drug-resistant tuberculosis (XDR TB).   view more (2007-10-23)

Clues to ensuring anti-HIV drugs are taken in Africa
HIV-infected patients in the African country of Tanzania were more likely to stop taking their medications and to fail treatment if they had to pay for the drugs themselves.   view more (2007-10-23)

Financial incentives may hold key to cutting child malaria deaths
Giving small financial incentives to health workers in low-income countries may hold the key to reducing the huge death toll from malaria in young children, according to a study published on bmj.com today.   view more (2007-10-23)

European drug regulations need to change, say experts
European drug regulations need changing to ensure they meet the needs of patients and doctors, argue experts in this week's BMJ.   view more (2007-10-19)

In vitro models will minimize animal use in arthritis studies
It's hard to think of scientists in laboratories working toward solutions for medical problems without mice or other laboratory animals, but animals' roles in at least one major research laboratory may soon be minimal.   view more (2007-10-18)

First high-res 3D structures of mammalian HSP90 protein solved
Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers.   view more (2007-10-15)

MIT links gene to cholesterol
MIT researchers have discovered a link between a gene believed to promote long lifespan and a pathway that flushes cholesterol from the body.   view more (2007-10-12)
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