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Paradigm shift: Switch for programmed cell death promotes spread of glioblastoma
Malignant tumors have usually lost their ability to destroy themselves by programmed cell death, or apoptosis. Therefore, tumors are often resistant to chemotherapy or radiation therapy, whose effect is based on forcing tumor cells to commit suicide.   view more (2008-03-12)

Wisconsin researchers describe how digits grow
Researchers at the University of Wisconsin School of Medicine and Public Health (SMPH) are wagging a finger at currently held notions about the way digits are formed.   view more (2008-03-12)

Post brain injury: New nerve cells originate from neural stem cells
Most cells in the human brain are not nerve cells, but supporting cells (glial cells). They serve as a framework for nerve cells and play an important role in the wound reaction that occurs with injuries to the brain.   view more (2008-03-12)

On a 'roll': MIT researchers devise new cell-sorting system
Capitalizing on a cell's ability to roll along a surface, MIT researchers have developed a simple, inexpensive system to sort different kinds of cells - a process that could result in low-cost tools to test for diseases such as cancer, even in remote locations.   view more (2008-03-10)

New stem cell technique improves genetic alteration
UC Irvine researchers have discovered a dramatically improved method for genetically manipulating human embryonic stem cells, making it easier for scientists to study and potentially treat thousands of disorders ranging from Huntington's disease to muscular dystrophy and diabetes.   view more (2008-03-10)

Gladstone scientists identify role of tiny RNAs in controlling stem cell fate
Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) and the University of California, San Francisco have identified for the first time how tiny genetic factors called microRNAs may influence the differentiation of pluripotent embryonic stem (ES) cells into cardiac muscle.   view more (2008-03-06)

UCLA researchers find blood stem cells originate and are nurtured in the placenta
Solving a long-standing biological mystery, UCLA stem cell researchers have discovered that blood stem cells, the cells that later differentiate into all the cells in the blood supply, originate and are nurtured in the placenta.   view more (2008-03-06)

Leicester scientists seek to disarm TB's 'molecular weapon'
Scientists at the University of Leicester are claiming a new advance in their fight against the resurgence of TB in Britain.   view more (2008-03-06)

Molecular alliance that sustains embryonic stem cell state
One of the four ingredients in the genetic recipe that scientists in Japan and the U.S. followed last year to persuade human skin cells to revert to an embryonic stem cell state, is dispensable in ES cells, thanks to the presence of a molecular alliance between a specific group of key proteins... view more (2008-03-05)

Iowa State University researcher identifies eye disease in canines
Sinisa Grozdanic, assistant professor of veterinary medicine at Iowa State University, has identified and named an eye disease not previously known. The disease, Immune-Mediated Retinopathy, or IMR, causes loss of function in retinal cells and, in some cases, blindness in canines.   view more (2008-03-05)

New target for cancer therapy may improve treatment for solid tumors
Targeting and killing the non-malignant cells that surround and support a cancer can stop tumor growth in mice, reports a research team based at the University of Chicago Medical Center in the March 1, 2008, issue of the journal Cancer Research. The discovery offers a new approach to treating... view more (2008-03-04)

Toxins in cigarette smoke prevent stem cells from becoming cartilage
A toxic pollutant spread by oil spills, forest fires and car exhaust is also present in cigarette smoke, and may represent a second way in which smoking delays bone healing, according to research presented today at the annual meeting of the Orthopaedic Research Society in San Francisco.   view more (2008-03-04)

Watery pools in bone marrow key to psoriatic arthritic damage
Researchers have learned more about how a leading drug prevents certain types of arthritis from eating away at bone, according to a study published in the March edition of the Annals of the Rheumatic Diseases.   view more (2008-03-04)

NIA uses Genomatix in stem cell research, suggests novel transcription factors for stemness
Genomatix Software with businesses in Munich, Germany and Ann Arbor, Michigan released today that the group of Kenneth R. Boheler at the National Institute on Aging, National Institutes of Health, Baltimore, Md published some remarkable work on embryonic stem (ES) cells.   view more (2008-03-04)

Blueberry and green tea containing supplement protects against stroke damage
A unique dietary supplement called NutraStem ® has been shown to have beneficial effects following experimental stroke. A nutritional supplement product, NutraStem also known as NT-020, is a proprietary formulation of blueberry, green tea, vitamin D3 and carnosine extracts- a combination of... view more (2008-03-04)

St. Jude researchers find key step in programmed cell death
Investigators at St. Jude Children's Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process.   view more (2008-03-03)

USC researchers discover novel way to develop tumor vaccines
Researchers at the University of Southern California (USC) have uncovered a new way to develop more effective tumor vaccines by turning off the suppression function of regulatory T cells.   view more (2008-03-03)

Adult stem cell changes underlie rare genetic disease associated with accelerated aging
Adult stem cells may provide an explanation for the cause of a Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).   view more (2008-03-03)

Short RNA strand helps exposed skin cells protect body from bacteria, dehydration and even cancer
Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier.   view more (2008-03-03)

First look: Princeton researchers peek into deepest recesses of human brain
A team of scientists from Princeton University has devised a new experimental technique that produces some of the best functional images ever taken of the human brainstem, the most primitive area of the brain.   view more (2008-02-29)

Rutgers Researchers Unlock Mysteries of Vitamin A Metabolism During Embryonic Development
Researchers at Rutgers have unlocked some of the mysteries of how the developing embryo reacts to fluctuations in the amount of vitamin A present in the maternal blood stream. Their results are presented in the February 28 issue of the Journal of Biological Chemistry.   view more (2008-02-29)

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma
A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous spontaneously.   view more (2008-02-28)

UT Knoxville research may lead to better flu vaccine
New research from a scientist at the University of Tennessee, Knoxville, has uncovered information that may someday lead to a better flu vaccine.   view more (2008-02-28)

Scientists discover how cigarette smoke causes cancer: Study points to new treatments, safer tobacco
Everyone has known for decades that that smoking can kill, but until now no one really understood how cigarette smoke causes healthy lung cells to become cancerous.   view more (2008-02-28)

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases
A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders.   view more (2008-02-27)
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