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Rutgers Researchers Unlock Mysteries of Vitamin A Metabolism During Embryonic Development
Researchers at Rutgers have unlocked some of the mysteries of how the developing embryo reacts to fluctuations in the amount of vitamin A present in the maternal blood stream. Their results are presented in the February 28 issue of the Journal of Biological Chemistry.   view more (2008-02-29)

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma
A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous spontaneously.   view more (2008-02-28)

UT Knoxville research may lead to better flu vaccine
New research from a scientist at the University of Tennessee, Knoxville, has uncovered information that may someday lead to a better flu vaccine.   view more (2008-02-28)

Scientists discover how cigarette smoke causes cancer: Study points to new treatments, safer tobacco
Everyone has known for decades that that smoking can kill, but until now no one really understood how cigarette smoke causes healthy lung cells to become cancerous.   view more (2008-02-28)

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases
A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders.   view more (2008-02-27)

Notch controls bone formation and strength
Notch, a protein known to govern the determination of cell differentiation into different kinds of tissues in embryos, plays a critical role in bone formation and strength later in life, said researchers from Baylor College of Medicine in Houston in a report that appears online today in the journal... view more (2008-02-25)

Immune deficiency and balance disorder result from single gene defect
A genetic defect that causes a severe immune deficiency in humans may also produce balance disorders, according to a new study by researchers at the University of Iowa, The Jackson Laboratory and East Carolina University.   view more (2008-02-22)

Modified electron microscope identifies atoms
A new electron microscope recently installed in Cornell's Duffield Hall is enabling scientists for the first time to form images that uniquely identify individual atoms in a crystal and see how those atoms bond to one another. And in living color.   view more (2008-02-22)

By color-coding atoms, new Cornell electron microscope promises big advance in materials analysis
A new electron microscope recently installed in Cornell's Duffield Hall is enabling scientists for the first time to form images that uniquely identify individual atoms in a crystal and see how those atoms bond to one another. And in living color.   view more (2008-02-22)

Tumor-killing virus selectively targets diseased brain cells
New findings show that a specialized virus with the ability to reproduce its tumor-killing genes can selectively target tumors in the brains of mice and eliminate them.   view more (2008-02-20)

Building brains: Mammalian-like neurogenesis in fruit flies
A new way of generating brain cells has been uncovered in Drosophila. The findings, published this week in the online open access journal Neural Development, reveal that this novel mode of neurogenesis is very similar to that seen in mammalian brains, suggesting that key aspects of neural... view more (2008-02-19)

Imitating monkey's 'jumping genes' could lead to new treatments for HIV
UCL (University College London) scientists have taken a significant step in understanding how retroviruses such as HIV can move between species and the biological mechanisms behind the 'jumping genes' which make some monkeys immune. They will now use this knowledge to develop a gene therapy... view more (2008-02-19)

Scientists move towards stem cell therapy trials to mend shattered bones
The UK Stem Cell Foundation, the Medical Research Council and Scottish Enterprise, in partnership with the Chief Scientist's Office, are funding a £1.4 million project to further the research at the University of Edinburgh with a view to setting up a clinical trial within two years.   view more (2008-02-19)

Protein maintains cross talk between cells that control hair growth
Genes, it turns out, are only as active as the signals that turn them on and off. Now scientists from Rockefeller University and the Howard Hughes Institute have identified the signaling molecule that ratchets up and clamps down the activity of key genes in dermal papilla, a type of skin cell whose... view more (2008-02-15)

How DDT metabolite disrupts breast cancer cells
Research has shown that the main metabolite of the insecticide DDT could be associated with aggressive breast cancer tumours, but there has been no explanation for this observation to date. Now a report published in the open access journal Breast Cancer Research shows how DDT could act to disrupt... view more (2008-02-14)

Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
Scientists in Switzerland are uncovering new clues about how cancer cells grow - and how they can be killed - by studying stem cells, 'blank' cells that have the potential to develop into fully mature or 'differentiated' cells and other scientists in UK have made a breakthrough in understanding the... view more (2008-02-14)

A functional immune system can be derived from embryonic stem cells, preliminary study finds
A new study demonstrates for the first time that embryonic stem cells can be used to create functional immune system blood cells, a finding which is an important step in the utilization of embryonic stem cells as an alternative source of cells for bone marrow transplantation.   view more (2008-02-13)

'Lab on a chip' mimics brain chemistry
Johns Hopkins researchers from the Whiting School of Engineering and the School of Medicine have devised a micro-scale tool - a lab on a chip - designed to mimic the chemical complexities of the brain. The system should help scientists better understand how nerve cells in the brain work together to... view more (2008-02-13)

Gene therapy protocol at UCSD activates immune system in patients with leukemia
A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.   view more (2008-02-12)

Discovery of good -- and bad -- liver stem cells raises possibility of new treatment
Many scientists believe up to 40 percent of liver cancer is caused by stem cells gone wild - master cells in the organ that have lost all growth control. But, despite years spent looking, no one has ever found these liver "cancer stem cells" - or even normal stem cells in the organ. Until... view more (2008-02-11)

How red blood cells nuke their nuclei
Unlike the rest of the cells in your body, your red blood cells lack nuclei. That quirk dates back to the time when mammals began to evolve. Other vertebrates such as fish, reptiles, and birds, have red cells that contain nuclei that are inactive. Losing the nucleus enables the red blood cell to... view more (2008-02-11)

Researchers discover new battleground for viruses and immune cells
Vaccines have led to many of the world's greatest public health triumphs, but many deadly viruses, such as HIV, still elude the best efforts of scientists to develop effective vaccines against them.   view more (2008-02-07)

More brain research suggests
Queensland Brain Institute (QBI) scientists have found another important clue to why nerve cells die in neurodegenerative diseases, based on studies of the developing brain.   view more (2008-02-07)

Chemical chaperone could open door to treatment of neurological disorder
An unexpected finding turned out to be a clue leading researchers at Washington University School of Medicine in St. Louis to propose a new treatment approach for Niemann-Pick disease, a rare, deadly neurodegenerative disorder.   view more (2008-02-06)

Prostate cancer: Watchful wait or vaccinate?
Researchers at the University of Southern California have developed a prostate cancer vaccine that prevented the development of cancer in 90 percent of young mice genetically predestined to develop the disease.   view more (2008-02-04)

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