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Cold Spring Harbor Protocols features methods for visualizing protein dynamics
This month's release of Cold Spring Harbor Protocols highlights methods that permit scientists to observe protein dynamics in chromosomes and embryos.   view more (2008-01-03)

Epilepsy and brain pathology linked together by the protein ADK
The brain of individuals who suffer from epilepsy is characterized by astrogliosis, a brain pathology evidenced by a complex series of changes in the morphology and function of brain cells known as astrocytes.   view more (2008-01-03)

Protein a possible key to allergy and asthma control
Activating a protein found on some immune cells seems to halt the cells' typical job of spewing out substances that launch allergic reactions, a study by Johns Hopkins researchers suggests. The findings could eventually lead to new treatments for allergic reactions ranging from annoying bouts of... view more (2008-01-03)

Protein a possible key to allergy and asthma control
Activating a protein found on some immune cells seems to halt the cells' typical job of spewing out substances that launch allergic reactions, a study by Johns Hopkins researchers suggests. The findings could eventually lead to new treatments for allergic reactions ranging from annoying bouts of... view more (2008-01-03)

Two Genes Are Important Key to Regulating Immune Response
A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10).   view more (2008-01-02)

Oliguridylation-mediated histone mRNA decay
In the January 1st issue of G&D, Drs. Thomas Mullen and William Marzluff (UNC Chapel Hill) lend new insight into the degradation of mammalian histone mRNA.   view more (2008-01-02)

Breast cancer cells have to learn to walk before they can run
Early-stage breast cancer that has not yet invaded the surrounding tissues may already contain highly motile cells, bringing the tumor one step closer to metastasis, report researchers at the Salk Institute for Biological Studies.   view more (2008-01-02)

FOXO factor promotes survival of oxygen-deprived cancer cells
Scientists report that an evolutionarily conserved transcription factor may have both positive and negative effects on the growth of tumors, depending on whether or not the tumor cells have enough oxygen.   view more (2007-12-28)

Baumann lab identifies elusive telomere RNA subunit in single cell model
The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model. Their findings have been posted to the Web site of the journal Nature Structural & Molecular Biology and will appear in a future print edition.   view more (2007-12-28)

Fight against hay fever and other allergies helped by new immune system discovery
A mechanism which can lead to hay fever and other allergic reactions, by preventing the immune system from regulating itself properly, has been discovered by scientists.   view more (2007-12-27)

Light powered platinum more targeted & 80 times more powerful than similar cancer treatments
Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light... view more (2007-12-26)

Translational research patented first experimental treatment against idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a disease with unknown cause with a very severe prognosis; when detected, it is already in an advanced stage.   view more (2007-12-26)

Cancer stem cells: know thine enemy
Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer.   view more (2007-12-26)

UC Irvine scientists find new way to sort stem cells
UC Irvine scientists have found a new way to sort stem cells that should be quicker, easier and more cost-effective than current methods. The technique could in the future expedite therapies for people with conditions ranging from brain and spinal cord damage to Alzheimer's and Parkinson's diseases.   view more (2007-12-21)

iNOS expression may links chronic biliary inflammation to malignant transformation
It is well known that chronic biliary inflammation is a risk factor for biliary carcinogenesis. However, the molecular mechanisms of biliary carcinogenesis as a consequence of chronic biliary inflammation remain unclear.   view more (2007-12-20)

Why don't we get cancer all the time?
The seemingly inefficient way our bodies replace worn-out cells is a defense against cancer, according to new research.   view more (2007-12-20)

Cancer and arthritis therapy may be promising treatment for diabetes
An antibody used to treat certain cancers and rheumatoid arthritis appears to greatly delay type 1 diabetes in mice, Yale School of Medicine researchers report in the Journal of Clinical Investigation.   view more (2007-12-19)

Intensive training post-spinal cord injury can stimulate repair in brain and spinal cord
Intensive rehabilitation training for patients with spinal cord injuries can stimulate new branches growing from severed nerve fibers, alongside compensatory changes in the brain, say Canadian researchers. Most importantly, it could lead to restoring hand function and the ability to walk.   view more (2007-12-19)

Researchers train the immune system to deliver virus that destroys cancer in lab models
An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts of the body through the lymphatic system.   view more (2007-12-19)

Widespread support for nonembryonic stem cell research, VCU Life Sciences Survey shows
The VCU Life Sciences Survey is the first poll to reflect the discovery reported internationally in November that human skin cells can be used to create stem cells or their near equivalents. When asked about the implications of this development, more than six in 10, or 63 percent, say that both... view more (2007-12-19)

OHSU research suggests new strategy for protecting aging Americans against infectious disease
Researchers at Oregon Health & Science University have uncovered new information about the body's immune system in a study that suggests new strategies may be in order for protecting the country's aging population against disease.   view more (2007-12-18)

MIT works toward engineered blood vessels
MIT scientists have found a way to induce cells to form parallel tube-like structures that could one day serve as tiny engineered blood vessels.   view more (2007-12-18)

CSHL scientists identify and repress breast cancer stem cells in mouse tissue
By manipulating highly specific gene-regulating molecules called microRNAs, scientists at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue - cells that are widely thought to give rise to cancer.   view more (2007-12-18)

UVA Reports Surprising Findings Related to Heart Protein, NKX2-5,
New research from the University of Virginia Health System shows that, in cases of Type 1 myotonic muscular dystrophy (DM1), a well known heart protein does several surprising things. DM1 is the most common form of muscular dystrophy in adults and affects approximately 40,000 adults and children in... view more (2007-12-18)

How size matters
The beauty of nature is partly due to the uniformity of leaf and flower size in individual plants, and scientists have discovered how plants arrive at these aesthetic proportions.   view more (2007-12-13)
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