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Washington University scientists first to sequence genome of cancer patient
For the first time, scientists have decoded the complete DNA of a cancer patient and traced her disease - acute myelogenous leukemia - to its genetic roots.   view more (2008-11-06)

Stanford research sheds light on key trigger of embryonic stem cell differentiation
Clusters of mouse embryonic stem cells called embryoid bodies more closely approximate true embryos in organization and structure than previously thought, according to researchers at the Stanford University School of Medicine. Harnessing the signals that influence the cells' fate may help... view more (2008-11-06)

Scripps research scientists identify compounds for stem-cell production from adult cells
In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects.   view more (2008-11-06)

MIT creates tiny backpacks for cells
MIT engineers have outfitted cells with tiny "backpacks" that could allow them to deliver chemotherapy agents, diagnose tumors or become building blocks for tissue engineering.   view more (2008-11-06)

Penn Scientists Show How Body Determines Optimal Amount of Germ-Fighting B Cells
Researchers at the University of Pennsylvania School of Medicine can now explain how the body determines whether there are enough mature B-cells in the blood stream at any one time. These are the cells that produce antibodies against germs to fight infections.   view more (2008-11-05)

Previously unknown immune cell may help those with Crohn's and colitis
The tonsils and lymphoid tissues in the intestinal tract that help protect the body from external pathogens are the home base of a rare immune cell newly identified by researchers at Washington University School of Medicine in St. Louis.   view more (2008-11-04)

MIT: Mending broken hearts with tissue engineering
Broken hearts could one day be mended using a novel scaffold developed by MIT researchers and colleagues.    view more (2008-11-03)

A double-barreled immune cell approach for neuroblastoma
Adding an artificial tumor-specific receptor to immune system cells called T-lymphocytes that target a particular virus extended and improved the cells' ability to fight a form of childhood cancer called neuroblastoma, said researchers form Baylor College of Medicine and Texas Children's Hospital... view more (2008-11-03)

How HIV vaccine might have increased odds of infection
In September 2007, a phase II HIV-1 vaccine trial was abruptly halted when researchers found that the vaccine may have promoted, rather than prevented, HIV infection.   view more (2008-11-03)

Stem cell therapies for heart disease -- 1 step closer
New research from the University of Bristol brings stem cell therapies for heart disease one step closer. The findings reveal that our bodies' ability to respond to an internal 'mayday' signal may hold the key to success for long-awaited regenerative medicine.   view more (2008-10-31)

Simple chemical procedure augments therapeutic potential of stem cells
Adult stem cells resemble couch potatoes if they hang out and divide in a dish for too long. They get fat and lose key surface proteins, which interferes with their movement and reduces their therapeutic potential. Now, via a simple chemical procedure, researchers have found a way to get these... view more (2008-10-31)

New drug target in obesity: Fat cells make lots of melanin
As millions of Americans gear up for the Thanksgiving holiday, a new research report published online in The FASEB Journal, may provide some relief for those leery of having a second helping.   view more (2008-10-30)

Syracuse University researchers discover new way to attack some forms of leukemia
Each year, some 29,000 adults and 2,000 children are diagnosed with leukemia, a form of cancer that is caused by the abnormal production of white blood cells in the bone marrow.   view more (2008-10-29)

In mice, anxiety is linked to immune system
In the first study ever to genetically link the immune system to normal behavior, scientists at Rockefeller and Columbia universities show that mast cells, known as the pharmacologic bombshells of the immune system, directly influence how mice respond to stressful situations.   view more (2008-10-28)

Researchers at UH Explore use of Fat Cells as Heart Attack Therapy
For those of us trained to read nutrition labels, conventional wisdom tells us that fat isn't good for the heart. But a team of University of Houston researchers has set out to use fat cells to beef up heart muscles damaged by heart attack - and they're using an out-of-this-world device to do it.    view more (2008-10-28)

Making flies sick reveals new role for growth factors in immunity
A Salmonella infection is not a positive experience. However, by infecting the common laboratory fruit fly Drosophila melanogaster with a Salmonella strain known for causing humans intestinal grief, researchers in the School of Life Sciences at Arizona State University have shed light on some key... view more (2008-10-27)

Mechanism in cells that generate malignant brain tumors may offer target for gene therapy
Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development of these cells from which malignant brain tumors may originate.   view more (2008-10-27)

MicroRNAs make for safer cancer treatments
Viruses -- long regarded solely as disease agents -- now are being used in therapies for cancer. Concerns over the safety of these so-called oncolytic viruses stem from their potential to damage healthy tissues.   view more (2008-10-27)

Building the blood-brain barrier
Construction of the brain's border fence is supervised by Wnt/b-catenin signaling, report Liebner et al. in The Journal of Cell Biology.    view more (2008-10-27)

Are bone marrow mononuclear cells effective in reducing hepatic lesions?
Liver fibrosis occurs in the setting of chronic injury caused by different etiologies constituting a serious worldwide public health problem. In addition to schistosomiasis, hepatopathies due to alcohol, viral hepatitis, drugs, metabolic and autoimmune diseases, and congenital abnormalities are... view more (2008-10-24)

Streamlining brain signals for speed and efficacy
Life exists at the edge of chaos, where small changes can have striking and unanticipated effects, and major stimuli may go unheard.   view more (2008-10-23)

What is the function of NOD2 in colonic epithelial cells?
NOD2 is a cytosolic pattern recognition receptor similar in structure and function to Toll like receptors (TLRs). It can recognize and respond to a component found in the cell wall of bacteria, muramyl dipeptide (MDP), and has been shown to play an important role in the innate immune response of... view more (2008-10-23)

Stem cell research to benefit horse owners and trainers
In a potential breakthrough for the performance horse industry (such as racing and polo), Melbourne scientists are aiming to harness stem cells to repair tendon, ligament, cartilage and bone damage in horses.   view more (2008-10-21)

Study links nicotine with breast cancer growth and spread
A study published in Cancer Research, a journal of the American Association for Cancer Research, suggests a possible role for nicotine in breast tumor development and metastases.   view more (2008-10-15)

Scientists trace molecular origin of proportional development
When it comes to embryo formation in the lowly fruit fly, a little molecular messiness actually leads to enhanced developmental precision, according to a study in the Oct. 14 Developmental Cell from Cincinnati Children's Hospital Medical Center.   view more (2008-10-14)
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