Recent Epigenetic Silencing Current Events | Epigenetic Silencing News
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Is hepatic differentiation of embryonic stem cells induced by valproic acid and cytokines?
Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. view more (2009-11-18)
Gerton Lab determines the composition of centromeric chromatin
The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical role in the process of mitosis. The work, conducted in yeast cells, was published in the most recent issue of Molecular Cell. view more (2009-09-29)
Weeding out marijuana: Researchers close in on engineering recognizable, drug-free Cannabis plant
In a first step toward engineering a drug-free Cannabis plant for hemp fiber and oil, University of Minnesota researchers have identified genes producing tetrahydrocannabinol (THC), the psychoactive substance in marijuana. Studying the genes could also lead to new and better drugs for pain, nausea and other conditions. view more (2009-09-16)
UCSB researchers develop drug delivery system using nanoparticles and lasers
Researchers at UC Santa Barbara have developed a new way to deliver drugs into cancer cells by exposing them briefly to a non-harmful laser. view more (2009-09-10)
Changes to DNA linked to diabetes
Genes that regulate the energy consumption of cells have a different structure and expression in type II diabetics than they do in healthy people, according to a new study from the Swedish medical university Karolinska Institutet published in Cell Metabolism. view more (2009-09-02)
PPAR-g agonists have potential therapeutic role in gastric carcinoma?
Recently, the potential of PPAR-γ as a target for the prevention and treatment of cancer has been widely studied. view more (2009-08-27)
Caltech researchers pinpoint neurons that control obesity in fruit flies
A team of scientists from the California Institute of Technology (Caltech) have pinpointed two groups of neurons in fruit fly brains that have the ability to sense and manipulate the fly's fat stores in much the same way as do neurons in the mammalian brain. view more (2009-08-19)
New method for gene expression experiments akin to watercolor painting in water
Like oil and water, two water-based liquids can mingle without mixing in a new University of Michigan technology developed for biological experiments. view more (2009-08-19)
Evolutionarily preserved mechanism governs use of genes
Researchers at Uppsala University have found that the protein coding parts of a gene are packed in special nucleosomes. The same type of packaging is found in the roundworm C elegans, which is a primeval relative of humans. view more (2009-08-18)
Scientists Take Early Steps Toward Mapping Epigenetic Variability
The study of eipigenetic variability in cells and tissues could someday help diagnose diseases more precisely and provide more targeted treatments for chronic ailments. view more (2009-08-17)
Gene shut-down may offer early warning of chronic leukemia
A new study shows that certain genes are turned off early, before clinical signs of the disease appear, in the development of chronic leukemia. view more (2009-08-06)
Silenced genes as a warning sign of blood cancer
In many types of cancer, parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This kind of methyl labeling ranges among the epigenetic changes that do not change the sequence of DNA building blocks. view more (2009-08-05)
Cancer's distinctive pattern of gene expression could aid early screening and prevention
Distinctive patterns of genes turned off - or left on - in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say. view more (2009-07-28)
Study reveals a reprogrammed role for the androgen receptor
The androgen receptor - a protein ignition switch for prostate cancer cell growth and division - is a master of adaptability. view more (2009-07-28)
Novel epigenetic markers of melanoma may herald new treatments for patients
Melanoma is the most serious form of skin cancer, diagnosed in more than 50,000 new patients in the United States annually. While the rate of incidences continues to rise, survival rate has not improved and the race is on to find the genetic and cellular changes driving melanoma and to devise new means of detection and treatment. view more (2009-06-30)
New Piece Found in the Puzzle of Epigenetics
A team of scientists led by Professor Dirk Eick of Helmholtz Zentrum München has identified the enzyme TFIIH kinase as an important factor in the epigenetic regulation of the cell nucleus enzyme RNA polymerase II. view more (2009-06-17)
An effective target of biological therapy for hepatocellular carcinoma
It has been shown that constitutively activated STAT3 is detected in many HCC cell lines and tissues. This suggests that STAT3 is a promising molecular target for HCC gene therapy. view more (2009-06-15)
A breakthrough in gastric carcinogenesis
Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. view more (2009-06-12)
Specific genetic cause of fetal alcohol-related developmental disorders found
Alcohol consumption by pregnant women hinders brain development in their children by interfering with the genetic processes that control thyroid hormone levels in the fetal brain, a new animal study found. view more (2009-06-11)
100 reasons to change the way we think about genetics
For years, genes have been considered the one and only way biological traits could be passed down through generations of organisms. view more (2009-05-19)
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