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Tamoxifen chemoprevention tied to early detection of breast cancer
The drug tamoxifen does not prevent or treat estrogen receptor (ER) negative breast cancer, but it can make the disease easier to find, researchers report in the Oct. 1 Journal of the National Cancer Institute.   view more (2008-10-08)

Herbal Menopause Therapy a Good Fit for Breast Cancer Patients?
When it comes to understanding the effectiveness and safety of using herbal therapies with other drugs, much is unknown. Now, a University of Missouri researcher will study how black cohosh - an herbal supplement often used to relieve hot flashes in menopausal women - interacts with tamoxifen, a... view more (2008-10-08)

Receptor could halt blinding diseases, stop tumor growth, preserve neurons after trauma
An international team of researchers has discovered what promises to be the on-off switch behind several major diseases.   view more (2008-10-07)

6 environmental research studies reveal critical health risks from plastic
Exposure to Bisphenol A (BPA), phthalates and flame retardants (PBDEs) are strongly associated with adverse health effects on humans and laboratory animals.   view more (2008-10-03)

Many receptor models used in drug design may not be useful after all
It may very well be that models used for the design of new drugs have to be regarded as impractical. This is the sobering though important conclusion of the work of two Leiden University scientists published in Science this week.   view more (2008-10-03)

Genes influence effectiveness of weight-loss drug
Obese patients with a specific genetic make-up lose more weight when taking the weight loss drug sibutramine and undergoing behavioral therapy compared to those without this genetic make-up, reports a new study in Gastroenterology, the official journal of the American Gastroenterological... view more (2008-10-02)

Extra copies of EGFR gene signal poor prognosis for vulvar cancer
A genetic fingerprint identified in patients with a gynecologic cancer may reveal candidates for targeted therapy.   view more (2008-10-01)

Researchers create first model for retina receptors
A team of scientists at the University of Oklahoma Health Sciences Center has created the first genetic research model for a microscopic part of the eye that when missing causes blindness. The research appears in a recent issue of the Journal of Biological Chemistry.    view more (2008-10-01)

MS patients have higher spinal fluid levels of suspicious immune molecule
A protein that helps keep immune cells quiet is more abundant in the spinal fluid of patients with multiple sclerosis (MS), further boosting suspicion that the protein, TREM-2, may be an important contributor to the disease.   view more (2008-09-30)

MIT paves way to 'artificial nose'
MIT biological engineers have found a way to mass-produce smell receptors in the laboratory, an advance that paves the way for "artificial noses" to be created and used in a variety of settings.   view more (2008-09-30)

Do 'light' cigarettes deliver less nicotine to the brain than regular cigarettes?
For decades now, cigarette makers have marketed so-called light cigarettes - which contain less nicotine than regular smokes - with the implication that they are less harmful to smokers' health. A new UCLA study shows, however, that they deliver nearly as much nicotine to the brain.   view more (2008-09-29)

Discovery offers new understanding of diabetes drug target
Scientists at the University of Leicester have published findings about a new advance in the study of major diabetes drug target.   view more (2008-09-26)

New predictive tool can help determine treatment of breast cancer patients
A new predictive measurement, called a PEPI score, could bring good news to many women diagnosed with early stage breast cancer - a low PEPI (preoperative endocrine prognostic index) score could show that they have little risk of relapse and can safely avoid chemotherapy after surgery.    view more (2008-09-24)

Is Bcl-2 protein a major obstacle in treating colorectal carcinoma?
Apoptosis resistance has been shown to contribute to the development of different cancer entities, such as colorectal carcinoma (CRC).   view more (2008-09-24)

The dietary supplement genistein can undermine breast cancer treatment
Women taking aromatase inhibitors to treat breast cancer or prevent its recurrence should think twice before also taking a soy-based dietary supplement, researchers report.   view more (2008-09-24)

Aspirin and atherosclerosis
Aspirin has become one of the most widely used medications in the world, owing to its ability to reduce pain, fevers, inflammation, and blood clotting.   view more (2008-09-23)

Is that song sexy or just so-so?
Why is your mate's rendition of Marvin Gaye's "Let's Get it On" cute and sexy sometimes and so annoying at other times? A songbird study conducted by Emory University sheds new light on this question, showing that a change in hormone levels may alter the way we perceive social cues by... view more (2008-09-23)

Breast cancer treatment resistance linked to signaling pathway
Activation of the Src signaling pathway may cause resistance to standard medical treatment in some patients with breast cancer, and inhibition of this pathway holds the potential to overcome that resistance, according to data presented here at the American Association for Cancer Research Molecular... view more (2008-09-23)

Variant of vitamin D receptor gene linked to melanoma risk
A new analysis indicates an association between a gene involved in vitamin D metabolism and skin cancer. Published in the November 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that individuals with certain variants in a vitamin D-related gene,... view more (2008-09-22)

New technique sees into tissue at greater depth, resolution
By coupling a kicked-up version of microscopy with miniscule particles of gold, Duke University scientists are now able to peer so deep into living tissue that they can see molecules interacting.   view more (2008-09-18)

New mechanism for cardiac arrhythmia discovered
It has long been thought that virus infections can cause cardiac arrhythmia. But why has not been understood. Ulrike Lisewski, Dr. Yu Shi, Michael Radke and Professor Michael Gotthardt of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now discovered the... view more (2008-09-18)

Expert urges FDA to take action to reduce BPA exposure
In the current issue of the Journal of the American Medical Association (JAMA), researchers report a significant relationship between urine concentrations of the environmental estrogen bisphenol A (BPA) and cardiovascular disease, type 2 diabetes and liver-enzyme abnormalities.   view more (2008-09-17)

Sun-damaged skin does not improve with estrogen treatments
Treating the skin with estrogen can stimulate collagen production-which improves the appearance of the skin-in areas not typically exposed to the sun, according to new research from the University of Michigan Health System.   view more (2008-09-16)

Wistar researchers invigorate 'exhausted' immune cells
In battles against chronic infections, the body's key immune cells often become exhausted and ineffective. Researchers at The Wistar Institute have found a way to restore vigor to these killer T cells by blocking a key receptor on their surface, findings that may advance the development of new... view more (2008-09-16)

Vaccine against HER2-positive breast cancer offers complete protection in lab
Researchers at Wayne State University have tested a breast cancer vaccine they say completely eliminated HER2-positive tumors in mice - even cancers resistant to current anti-HER2 therapy - without any toxicity.   view more (2008-09-15)
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