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Wistar researchers invigorate 'exhausted' immune cells
In battles against chronic infections, the body's key immune cells often become exhausted and ineffective. Researchers at The Wistar Institute have found a way to restore vigor to these killer T cells by blocking a key receptor on their surface, findings that may advance the development of new... view more (2008-09-16)

Vaccine against HER2-positive breast cancer offers complete protection in lab
Researchers at Wayne State University have tested a breast cancer vaccine they say completely eliminated HER2-positive tumors in mice - even cancers resistant to current anti-HER2 therapy - without any toxicity.   view more (2008-09-15)

New cannabis-like drugs could block pain without affecting brain, says study
A new type of drug could alleviate pain in a similar way to cannabis without affecting the brain, according to a new study published in the journal Pain on Monday 15 September.   view more (2008-09-12)

Gap junction protein vital to successful pregnancy, researchers find
Researchers studying a critical stage of pregnancy - implantation of the embryo in the uterus - have found a protein that is vital to the growth of new blood vessels that sustain the embryo. Without this protein, which is produced in higher quantities in the presence of estrogen, the embryo is... view more (2008-09-11)

Cortisol and fatty liver: Researchers find cause of severe metabolic disorders
A healthy body stores fat in the form of so-called triglycerides in specialized fatty tissue as an energy reserve. Under certain conditions the delicate balance of the lipid metabolism gets out of control and fat is accumulated in the liver, leading to the dreaded fatty liver.   view more (2008-09-10)

Protein found that regulates gene critical to dopamine-releasing brain cells
Researchers have identified a protein they say appears to be a primary player in maintaining normal functioning of an important class of neurons - those brain cells that produce, excrete and then reabsorb dopamine neurotransmitters.   view more (2008-09-10)

Bisphenol A linked to metabolic syndrome in human tissue
New research from the University of Cincinnati (UC) implicates the primary chemical used to produce hard plastics-bisphenol A (BPA)-as a risk factor for metabolic syndrome and its consequences.   view more (2008-09-05)

Blood vessel cells are instructed to form tube-like structures
How do blood vessel cells understand that they should organise themselves in tubes and not in layers? A research group from Uppsala University shows for the first time that a special type of "instructor" molecule is needed to accomplish this. These findings, published in the scientific... view more (2008-08-29)

Potential new targets for antidepressant medications
The news about antidepressant medications over the past several years has been mixed. The bad news from large multicenter studies such as STAR*D is that current antidepressant medications are effective, but not as effective as one might hope. Thus, there is a significant need for new treatment... view more (2008-08-27)

Looking beyond the drug receptor for clues to drug effectiveness
Antipsychotic drugs that are widely used to treat schizophrenia and other problems may not work as scientists have assumed, according to findings from Duke University Medical Center researchers that could lead to changes in how these drugs are developed and prescribed.   view more (2008-08-26)

Going from ulcers to cancer
Researchers have uncovered a big clue as to why some of the bacteria that cause stomach ulcers pose a greater risk for serious problems like stomach cancer than others; it turns out these bacteria can exploit the surrounding stomach cells to protect them from the immune system.   view more (2008-08-25)

Researchers uncover molecule that keeps pathogens like salmonella in check
Scientists at UT Southwestern Medical Center have found a potential new way to stop the bacteria that cause gastroenteritis, tularemia and severe diarrhea from making people sick.   view more (2008-08-22)

Why a common treatment for prostate cancer ultimately fails
Some of the drugs given to many men during their fight against prostate cancer can actually spur some cancer cells to grow, researchers have found. The findings were published online this week in a pair of papers in the Proceedings of the National Academy of Sciences.   view more (2008-08-22)

Cocaine: How addiction develops
Permanent drug seeking and relapse after renewed drug administration are typical behavioral patterns of addiction. Molecular changes at the connection points in the brain's reward center are directly responsible for this.   view more (2008-08-22)

Experiments could lead to new treatments for neuroblastoma
Neuroblastoma is one of the most devastating diagnoses a child can receive. The cancer's victims average 2 years old when the disease is detected, most often by a parent feeling a lump in a child's abdomen. By then, the disease has often reached an advanced stage, and advanced neuroblastoma kills... view more (2008-08-18)

Scientists discover major genetic cause of colorectal cancer
About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases.   view more (2008-08-15)

Cocaine-induced synaptic plasticity linked to persistent addictive behaviors
The persistent nature of addiction is its most devastating feature. Understanding the mechanism underlying this phenomenon is the key for designing efficient therapy. Two separate studies published by Cell Press is the August 14 issue of the journal Neuron identify specific cocaine-induced changes... view more (2008-08-14)

The pandemic potential of H9N2 avian influenza viruses
Since their introduction into land-based birds in 1988, H9N2 avian influenza A viruses have caused multiple human infections and become endemic in domestic poultry in Eurasia.   view more (2008-08-13)

Halting retrieval of drug-associated memories may prevent addiction relapse
Disrupting the brain's retrieval of drug-associated memories may prevent relapse in drug addiction, according to new research in the August 13 issue of The Journal of Neuroscience.   view more (2008-08-13)

'Erasing' drug-associated memories may stop drug addiction relapses
'Erasing' drug-associated memories may prevent recovering drug abusers from relapsing, researchers at the University of Cambridge have discovered.    view more (2008-08-13)

Risk assessment plays key role in long-term treatment of breast cancer
Breast cancer patients and their physicians may make more informed, long-term treatment decisions using risk assessment strategies to help determine probability of recurrence.   view more (2008-08-13)

If your first cigarette gave you a buzz and you now smoke, a gene may be to blame
Anyone who has ever tried smoking probably remembers that first cigarette vividly. For some, it brought a wave of nausea or a nasty coughing fit. For others, those first puffs also came with a rush of pleasure or "buzz."   view more (2008-08-11)

In scientific first, Einstein researchers correct decline in organ function associated with old age
As people age, their cells become less efficient at getting rid of damaged protein - resulting in a buildup of toxic material that is especially pronounced in Alzheimer's, Parkinson's disease, and other neurodegenerative disorders.   view more (2008-08-11)

Hot peppers really do bring the heat
Chili peppers can do more than just make you feel hot, reports a study in the August 1 Journal of Biological Chemistry; the active chemical in peppers can directly induce thermogenesis, the process by which cells convert energy into heat.    view more (2008-08-07)

Estrogen relieves psychotic symptoms in women with schizophrenia
When combined with antipsychotic medications, the estrogen estradiol appears to be a useful treatment in women with schizophrenia, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.   view more (2008-08-05)
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