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Zebrafish enable scientists to study the migration of neurons that enable sexual maturity
Scientists are watching a small group of neurons that enable sexual maturity and fertility make a critical journey: from where they form, near the developing nose, to deep inside the brain.   view more (2008-06-05)

Long-term hormone replacement therapy increases breast cancer risk
"Are you taking or did you take hormones? If yes, which hormone medication and for how long? When did you stop taking hormone replacement medication?" 3,464 breast cancer patients and 6,657 healthy women between the ages of 50 and 74 years participated in a large survey and elicited... view more (2008-05-29)

Fruit fly protein acts as decoy to capture tumor growth factors, find Penn researchers
Researchers at the University of Pennsylvania School of Medicine have shown how Argos, a fruit fly protein, acts as a ¡¥decoy' receptor, binding growth factors that promote the progression of cancer.   view more (2008-05-29)

New study shows sedentary high school girls are at significant risk for future osteoporosis
Significant numbers of female high school athletes and non-athletes suffer from one or more components of the female athlete triad, a combination of three conditions that can lead to cardiovascular disease, according to a new study by Medical College of Wisconsin researchers in Milwaukee.   view more (2008-05-29)

Estrogen Helps Drive Distinct, Aggressive Form of Prostate Cancer
Using a breakthrough technology, researchers led by a Weill Cornell Medical College scientist have pinpointed the hormone estrogen as a key player in about half of all prostate cancers.   view more (2008-05-28)

Blood cholesterol levels predict risk of heart disease due to hormone therapy
A new analysis of a subgroup of participants in the Women's Health Initiative (WHI) hormone therapy clinical trials suggests that healthy, postmenopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy.   view more (2008-05-27)

Oocyte-specific gene mutations cause premature ovarian failure
Mutations in a gene called FIGLA cause premature ovarian failure in at least a percentage of women who suffer from the disorder, said researchers from Baylor College of Medicine in Houston and Shandong University in China in a report that appears online today in the American Journal of Human... view more (2008-05-23)

Study finds it pays to be heart smart if considering hormone therapy
A research study has found that a simple blood test may indicate whether post-menopausal hormone therapies present an elevated risk of a heart attack.   view more (2008-05-22)

Iressa shows promise for treatment of metastatic breast cancer when combined with hormonal therapy
Gefitinib, the once-promising drug formerly approved as a second line treatment for lung cancer, also known as Iressa, enhanced the effectiveness of hormonal therapy for the treatment of specific types of metastatic breast cancer.   view more (2008-05-19)

Disabling mouse enzyme increases fertility
Changing the sugars attached to a hormone produced in the pituitary gland increased fertility levels in mice nearly 50 percent, a research group at Washington University School of Medicine in St. Louis has found.   view more (2008-05-19)

Ashwell receptor reduces mortality during sepsis
In research that solves the longest-standing mystery in glycobiology - a field that studies complex sugar chains called glycans - researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is... view more (2008-05-19)

Treating osteoporosis calls for physician, dentist collaboration: ADA Journal
Physicians and dentists should collaborate to improve early detection and treatment of patients who have or may develop osteoporosis, say researchers in the cover story of the May issue of The Journal of the American Dental Association.   view more (2008-05-16)

New Mount Sinai research tracks effects of addictive drugs on brain
Mount Sinai researchers may have unlocked the key to better understanding the effect addictive drugs have on the human brain.   view more (2008-05-16)

U of Minnesota researcher discovers the starting point of sun-induced skin cancer
According to a new study from the University of Minnesota, the earliest event in the development of sun-induced skin cancer may have been identified.   view more (2008-05-15)

St. Jude study shows how T cell's machinery dials down autoimmunity
A St. Jude Children's Research Hospital study shows that T cells, the body's master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust... view more (2008-05-13)

Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute.   view more (2008-05-09)

Depression diversity: Brain studies reveal big differences among individuals
Depressed people may have far fewer of the receptors for some of the brain's "feel good" stress-response chemicals than non-depressed people, new University of Michigan Depression Center research shows.   view more (2008-05-08)

Killer competition: Neurons duke it out for survival
The developing nervous system makes far more nerve cells than are needed to ensure target organs and tissues are properly connected to the nervous system. As nerves connect to target organs, they somehow compete with each other resulting in some living and some dying.   view more (2008-05-07)

The tachykinin receptor 3 gene has been linked to alcohol and cocaine dependence
The search for genes associated with alcohol dependence has recently been extended to the tachykinin receptor 3 gene, located within a broad region on chromosome 4q. Researchers have found that seven of the nine single nucleotide polymorphisms -- DNA sequence variations -- in the 3' region of TACR3... view more (2008-05-06)

Unexpected role: EGFR protects cancer cells from starving
A growth factor receptor found abundantly on the surface of cancer cells and long known to fuel cancer growth also protects tumor cells from starvation by a newly identified mechanism.   view more (2008-05-06)

A new idea for how anti-aging products delay ripening of fruit and wilting of flowers
When plants encounter ethylene, a gas they also produce naturally as a hormone, the result is softening and ripening in the case of fruit, and wilting and fading in the case of flowers - all of which ethylene promotes.   view more (2008-05-05)

Treatment advances for fibroids, menopause
Women with fibroids and endometriosis facing the possibility of hysterectomy may now choose less invasive treatment options to preserve fertility, according to Yale professor Aydin Arici, M.D., who will direct a scientific session exploring these alternatives at the American College of... view more (2008-05-05)

Study raises questions about prostate cancer therapies targeting IGF-1
Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene - p53 - is already compromised, according to new research by investigators... view more (2008-05-01)

Gastric juice for diagnosis of H. pylori infection in patients on proton pump inhibitors
This study determined the efficiency of a gastric juice PCR test for the detection of H. pylori infection in patients receiving PPI therapy and compared it with histology and gastric biopsy PCR.   view more (2008-04-30)

Osteoporosis drug Fosamax linked to heart problem
omen who have used Fosamax are nearly twice as likely to develop the most common kind of chronically irregular heartbeat (atrial fibrillation) than are those who have never used it, according to research from Group Health and the University of Washington published in the April 28 Archives of... view more (2008-04-29)
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