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Scripps research scientists identify compounds for stem-cell production from adult cells
In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects.   view more (2008-11-06)

Existing anti-obesity drugs may be effective against flu, hepatitis and HIV
Viruses dramatically increase cellular metabolism, and existing anti-obesity drugs may represent a new way to block these metabolic changes and inhibit viral infection, according to a study published today in the journal Nature Biotechnology.    view more (2008-09-29)

New source of heart stem cells discovered
Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells.   view more (2008-06-23)

Good news for a fast-wrinkling generation: Some anti-aging methods work
Fine wrinkles, deeper creases, saggy areas around the mouth and neck - the sights in the mirror that make baby boomers wince - are not inevitable. They result from a structural breakdown inside the skin that some existing treatments effectively counteract by stimulating the growth of new, youthful... view more (2008-05-29)

Scientists identify novel way to prevent cardiac fibrosis
In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by... view more (2008-04-23)

Location matters, even for genes
Moving an active gene from the interior of the nucleus to its periphery can inactivate that gene report scientists from the University of Chicago Medical Center in an article to be published early online Feb.13, 2008, in the journal Nature.   view more (2008-02-14)

Molecular pathway appears crucial in development of pulmonary fibrosis
A study led by Massachusetts General Hospital (MGH) researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis (IPF), a usually fatal lung disease for which transplantation is the only successful treatment.   view more (2007-12-13)

Scientists identify embryonic stem cells by appearance alone
Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait.   view more (2007-08-28)

Stanford researchers find culprit in aging muscles that heal poorly
Communication is critical. Garbled in, garbled out, so to (mis-)speak. Workers who get incomplete instructions produce an incomplete product, and that's exactly what happens with the stem cells in our aging muscles.   view more (2007-08-10)

New UD tissue-engineering research focuses on vocal cords
Damaged or diseased vocal cords can forever change and even silence the voices we love, from a family member's to a famous personality's.   view more (2007-08-01)

Study helps explain origins of cardiac fibrosis in patients with heart disease
A report led by researchers at Beth Israel Deaconess Medical Center (BIDMC) helps explain the origins of cardiac fibrosis, a stiffening of the heart muscle that leads to a variety of cardiac diseases, most notably heart failure.   view more (2007-07-30)

Deakin University research finds rogue cells that could cause spread of breast cancer
Stephanie Lebret completed the study for her PhD at Deakin's Centre for Cellular and Molecular Biology under the supervision of Associate Professor Leigh Ackland.   view more (2007-06-14)

UCLA researchers reprogram normal tissue cells into embryonic stem cells
Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.   view more (2007-06-07)

A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline.   view more (2007-06-07)

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease typically characterized by the slow but progressive onset of shortness of breath or cough.   view more (2007-05-31)

Scientists develope a new model of artificial canine skin
Researchers at UNIVET, a spin-off of the Universitat Autònoma de Barcelona, in cooperation with the animal nutrition company Affinity Petcare, have developed an artificial cellular model which faithfully reproduces the characteristics of dog's skin and which will allow, therefore, the... view more (2007-05-11)

Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint.   view more (2007-04-30)

Green tea compound may be a therapy for people with rheumatoid arthritis
A new study from the University of Michigan Health System suggests that a compound in green tea may provide therapeutic benefits to people with rheumatoid arthritis.   view more (2007-04-30)

Anti-wrinkle compound causes pathological reaction in skin cells
Researchers from Université Laval's Faculty of Medicine have discovered that a compound commonly used in many antiwrinkle products causes a pathological reaction in skin cells.   view more (2007-04-12)

Cells selectively absorb short nanotubes
DNA-wrapped single-walled carbon nanotubes (SWCNTs) shorter than about 200 nanometers readily enter into human lung cells and so may pose an increased risk to health, according to scientists at the National Institute of Standards and Technology (NIST). The results of their laboratory studies appear... view more (2007-04-02)

Scientists unlock mystery of embryonic stem cell signaling pathway
A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently... view more (2007-03-20)

Proteasome activator enhances survival of Huntington's disease neuronal model cells
To function, each living cell needs both to build new and to degrade old or damaged proteins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins.   view more (2007-02-28)

Injection of 'skin filler' material appears to stimulate collagen production
Injections with "dermal fillers" containing hyaluronic acid appear to stimulate production of collagen, a primary protein in the skin, and may partially restore the structure of sun-damaged skin, according to an article in the February issue of Archives of Dermatology, one of the... view more (2007-02-20)

Mice cloned from skin cells
Healthy and viable mice that survive until adulthood have, for the first time, been cloned from adult stem cells. Scientists from Rockefeller University, including Howard Hughes Medical Institute investigator Elaine Fuchs, used cells called keratinocyte stem cells, which represent a new model... view more (2007-02-13)

Brown Cancer Biologists Identify Major Player in Cell Growth
When cells go about the business of dividing, they can get sidelined. Maybe there aren't enough nutrients. Maybe there aren't the right signals to resume multiplying. Either way, cells go quiet.   view more (2007-02-07)
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