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Angiochem crosses BBB, shows safety, efficacy in phase 1/2 brain cancer studies
Angiochem, Inc. a clinical-stage biotechnology company developing drugs that are uniquely capable of crossing the blood-brain barrier to treat brain diseases, announced today that its lead drug candidate, ANG1005, has demonstrated a favorable safety and efficacy profile in more than 100 patients with brain cancer from two separate Phase 1 /2... view more... (2009-10-19)

Toward a nanomedicine for brain cancer
In an advance toward better treatments for the most serious form of brain cancer, scientists in Illinois are reporting development of the first nanoparticles that seek out and destroy brain cancer cells without damaging nearby healthy cells.   view more (2009-09-10)

GEN reports on expanding NextGen sequencing applications
Next-Generation Sequencing (NGS) technologies are not only beginning to supplant traditional Sanger sequencing methodology but are also giving DNA microarrays a run for the money as well, reports Genetic Engineering & Biotechnology News (GEN).   view more (2009-09-04)

Avastin dramatically improves response, survival in deadly recurrrent glioblastomas
The targeted therapy Avastin, alone and in combination with the chemotherapy drug CPT-11, significantly increased response rates, progression-free survival times and survival rates in patients with a deadly form of brain cancer that had recurred.   view more (2009-09-03)

Why don't brain tumors respond to medication?
Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance.   view more (2009-09-01)

NIH researchers identify key factor that stimulates brain cancer cells to spread
Researchers funded by the National Institutes of Health have found that the activity of a protein in brain cells helps stimulate the spread of an aggressive brain cancer called glioblastoma multiforme (GBM).   view more (2009-08-19)

Anti-psychotic drugs could help fight cancer
The observation that people taking medication for schizophrenia have lower cancer rates than other people has prompted new research revealing that anti-psychotic drugs could help treat some major cancers.   view more (2009-08-12)

STAT3 Gene Regulates Cancer Stem Cells in Brain Cancer
In a study published online in advance of print in Stem Cells, Tufts researchers report that the STAT3 gene regulates cancer stem cells in brain cancer. Cancer stem cells have many characteristics of stem cells and are thought to be the cells that drive tumor formation.   view more (2009-08-10)

Sensitizing tumor response to cancer therapy
Two forms of skin and brain cancer respond very poorly to chemotherapy and radiation: melanoma and glioblastoma multiforme brain cancer.   view more (2009-08-06)

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers
Cancer researchers at Georgetown University's Lombardi Comprehensive Cancer Center have successfully tested a small, engineered antibody they say shuts down growth of human glioblastoma tumors in cell and animal studies. Glioblastoma is the deadliest of brain cancers; there is no effective treatment.   view more (2009-07-31)

A crystal ball for brain cancer?
UCLA researchers have uncovered a new way to scan brain tumors and predict which ones will be shrunk by the drug Avastin -- before the patient ever starts treatment.   view more (2009-07-30)

New strategy in tumor treatment
A new strategy proposed by researchers at Dartmouth Medical School and Amtek, Hanover, NH may treat tumors that do not respond to conventional treatment.   view more (2009-07-20)

Stealthy gene network makes brain tumors flourish
The brain tumor afflicting Sen. Edward Kennedy - a glioblastoma - is the most aggressive and wily form of brain cancer.   view more (2009-07-15)

Variations in 5 genes raise risk for most common brain tumors
Common genetic variations spread across five genes raise a person's risk of developing the most frequent type of brain tumor, an international research team reports online in Nature Genetics.   view more (2009-07-06)

DNA variations linked to brain tumors
Mayo Clinic researchers and colleagues at the University of California San Francisco (UCSF) have found a connection between DNA alterations on human chromosome 9 and aggressive brain cancer known as glioblastoma.   view more (2009-07-06)

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment
A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme.   view more (2009-07-01)

Biomarkers predict brain tumor's response to therapy
A report in Cancer Research, a journal of the American Association for Cancer Research, highlights a new biomarker that may be useful in identifying patients with recurrent glioblastoma, or brain tumors, who would respond better to anti-vascular endothelial growth factor therapy, specifically cediranib.   view more (2009-06-24)

Most common brain cancer may originate in neural stem cells
University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer.   view more (2009-06-02)

Cottonseed-Based Drug Shows Promise Treating Severe Brain Cancer, Say UAB Researchers
An experimental drug derived from cottonseeds shows promise in treating the recurrence of glioblastoma multiforme, widely considered the most lethal brain cancer.   view more (2009-05-29)

Novel cancer drug reduces neuroblastoma growth by 75 percent
Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found a new drug that restricts the growth of neuroblastoma, a childhood brain cancer.   view more (2009-04-24)
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