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Hearing restoration may be possible with cochlear repair after transplant of human cord blood cells
According to an Italian research team publishing their findings in the current issue of Cell Transplantation (17:6), hearing loss due to cochlear damage may be repaired by transplantation of human umbilical cord hematopoietic stem cells (HSC) since they show that a small number migrated to the... view more (2008-09-04)

Protein key to control, growth of blood cells
New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and may lead to better treatments for life-threatening blood diseases.   view more (2008-08-14)

Predicting acute GVHD by gene expression could improve liver stem cell transplant outcomes
Many cell transplants involve the use of stem cells from another human being (known as an allograft), which raises the major concern of the potential for acute graft-versus-host disease (GVHD).   view more (2008-07-21)

Human embryonic stem cells developed from 4-cell embryo; world first may lessen ethical concerns
For the first time in the world scientists have succeeded in developing human embryonic stem cells (hESCs) from a single cell, or blastomere, of a 4-cell stage embryo.   view more (2008-07-09)

Predicting the risk of a common fungal infection after stem cell transplantation
In silico genetic analysis in mice has led to the discovery of a gene affecting susceptibility to a severe fungal infection in transplant recipients.   view more (2008-06-20)

Inflammation triggers cell fusions that could protect neurons, Stanford research shows
Chronic inflammation triggers bone marrow-derived blood cells to travel to the brain and fuse with a certain type of neuron up to 100 times more frequently than previously believed, according to a new study from the Stanford University School of Medicine.   view more (2008-04-21)

Cells on path to becoming mature T-cells more flexible than commonly thought
Contrary to the currently accepted model of T-cell development, researchers at the University of Pennsylvania School of Medicine have found that juvenile cells on their way to becoming mature immune cells can develop into either T cells or other blood-cell types versus only being committed to the... view more (2008-04-10)

NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis.   view more (2008-03-27)

UCLA researchers find blood stem cells originate and are nurtured in the placenta
Solving a long-standing biological mystery, UCLA stem cell researchers have discovered that blood stem cells, the cells that later differentiate into all the cells in the blood supply, originate and are nurtured in the placenta.   view more (2008-03-06)

St. Jude researchers find key step in programmed cell death
Investigators at St. Jude Children's Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process.   view more (2008-03-03)

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases
A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders.   view more (2008-02-27)

A functional immune system can be derived from embryonic stem cells, preliminary study finds
A new study demonstrates for the first time that embryonic stem cells can be used to create functional immune system blood cells, a finding which is an important step in the utilization of embryonic stem cells as an alternative source of cells for bone marrow transplantation.   view more (2008-02-13)

Ireland Cancer Center researchers advance stem cell gene therapy
Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with... view more (2007-12-13)

Blood stem cells fight invaders, study finds
No other stem cell is more thoroughly understood than the blood, or hematopoietic, stem cell.   view more (2007-11-30)

St. Jude settles century-old debate on origin of mammalian network of lymphatic vessels
Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature-the network of vessels and capillaries critical to various essential housekeeping functions in the body. The finding holds the promise for the development of new... view more (2007-10-04)

Aspartame is safe, study says
Looking at more than 500 reports, including toxicological, clinical and epidemiological studies dating from 1970's preclinical work to the latest studies on the high-intensity sweetener, along with use levels and regulations data, an international expert panel from 10 universities and medical... view more (2007-09-12)

Pittsburgh scientists identify human source of stem cells with potential to repair muscle
For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy.   view more (2007-09-05)

U-M team identifies gene that regulates blood-forming fetal stem cells
In the rancorous public debate over federal research funding, stem cells are generally assigned to one of two categories: embryonic or adult.   view more (2007-07-27)

MicroRNA works with Ago2 protein to regulate blood cell development
MicroRNAs became the stars of the RNA universe when, in 2001, scientists found that these short RNAs can control whether or not genes are expressed.   view more (2007-07-27)

Effects of aging in stem cells
There is little disagreement that the body's maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why.   view more (2007-07-24)

Toxic milk
In the August 1 issue of G&D, Dr. Ronald Evans (Salk Institute) and colleagues report on their discovery that mutations in the mouse gene encoding PPARγ adversely affect lactation milk quality, and have serious health consequences for nursing pups.   view more (2007-07-24)

Ago2 and hematopoiesis
Argonaute 2 (Ago2) is unique among its family: It is the only one of the four mammalian Argonaute proteins that exhibits endonuclease "slicer" activity (facilitation of miRNA-guided cleavage of target mRNA).   view more (2007-07-12)

Hepatitis C increases risk of non-Hodgkin lymphoma
Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma (malignancy involving lymphatic tissue) of 20 percent to 30 percent, and a three-fold increase in the risk of another type of lymphoma, according to a study in the May 9 issue of JAMA.   view more (2007-05-09)

Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body.   view more (2007-04-19)

Study suggests use of stem cell transplantation is beneficial treatment of type 1 diabetes
A therapy that includes stem cell transplantation induced extended insulin independence in patients with type 1 diabetes mellitus.   view more (2007-04-11)
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