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Study suggests use of stem cell transplantation is beneficial treatment of type 1 diabetes
A therapy that includes stem cell transplantation induced extended insulin independence in patients with type 1 diabetes mellitus.   view more (2007-04-11)

CDX2 — A protein that promotes leukemia
Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells.   view more (2007-03-08)

New hope for regenerative medicine
In the February 15th issue of G&D, Dr. K. John McLaughlin and colleagues report on their success in using uniparental embryonic stem cells to replace blood stem cells in mice.   view more (2007-02-15)

Grafts against cancer
A research team led by Prof. Claude Perreault, Université de Montréal, is announcing a major discovery in Genomics. This will generate a fundamental impact on the treatment of blood cancers (leukemias and lymphomes) by means of peripheral blood T-cell grafts.   view more (2007-02-02)

Researchers find stem-cell therapy effective in targeting metastatic cancer
Patients with advanced cancer that has spread to many different sites often do not have many treatment options, since they would be unable to tolerate the doses of treatment they would need to kill the tumors.   view more (2006-12-21)

Molecular 'marker' on stem cells aids research, perhaps therapies
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT... view more (2006-12-04)

Cloned mice created from fully differentiated cells, a milestone in cloning research
New research dismisses the notion that adult stem cells are necessary for successful animal cloning, proving instead that cells that have completely evolved to a specific type not only can be used for cloning purposes, but they may be a better and more efficient starting point.   view more (2006-10-02)

Studies find general mechanism of cellular aging
Three separate studies confirm a gene that suppresses tumor cell growth also plays a key role in aging.   view more (2006-09-07)

Lost in the labyrinth
Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves, and turning these into the blood cell types needed by the body.   view more (2006-09-05)

Can you hear me now? Scientists find previously unknown receptors on adult stem cells
For many years, researchers believed that stem cells in the bone marrow spent most of their existence in a slumber-like state, unaware of — and unaffected by — the daily battles fought by the body's immune system.   view more (2006-06-21)

Bones hold the key to blood renewal
Though we think of them as solid and permanent, our bones are actually constantly being rebuilt throughout our lives. A team of scientists at the Weizmann Institute of Science has now revealed how cells that work at remodeling the bones play a direct part in the ongoing renewal of another system... view more (2006-06-20)

OHSU study says stem cell 'fusion' occurs in tumors
An Oregon Health & Science University study is adding credence to an increasingly popular theory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue.   view more (2006-05-10)

U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.   view more (2006-02-14)

Research shows promise for using stem cell transplantation to treat patients with severe lupus
About half of patients with severe lupus that was refractory to standard treatment and who underwent autologous stem cell transplantation to improve their immune system have substantial improvement in disease activity after several years.   view more (2006-02-01)

Mad-cow culprit maintains stem cells
What do mad cow disease and stem cell research have in common? Whitehead Institute scientists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain... view more (2006-01-31)

Discoveries may advance stem cell therapy for Parkinson's, cancer patients
Two studies in the Jan. 27, 2006 Cell have yielded evidence that could prove a boon for stem cell therapies aimed at patients with Parkinson's disease and those with compromised immune systems due to intensive cancer therapy or autoimmune disease, according to researchers.   view more (2006-01-27)

Role of the nervous system in regulating stem cells discovered
New study by Mount Sinai researchers may lead to improved stem cell therapies for patients with compromised immune systems due to intensive cancer therapy or autoimmune disease.   view more (2006-01-27)

Powerful technique for multiplying adult stem cells may aid therapies
Adult stem cells may be free of the ethical concerns that hamper embryonic stem cell research, but they still pose formidable scientific challenges. Chief among these is the doggedness with which adult stem cells differentiate into mature tissue the moment they're isolated from the body.   view more (2006-01-23)

Study identifies molecule essential for proper localization of blood stem cells
Scientists at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HCSI) have defined a molecule that dictates how blood stem cells travel to the bone marrow and establish blood and immune cell production.   view more (2006-01-16)

Sickle cell disease corrected in human models using stem cell-based gene therapy
In a study to be published in the January 2006 issue of Nature Biotechnology, researchers led by a team of scientists at Memorial Sloan-Kettering Cancer Center have devised a novel strategy that uses stem cell-based gene therapy and RNA interference to genetically reverse sickle cell disease (SCD)... view more (2005-12-29)

New study expands understanding of the role of RNA editing in gene control
For many years, scientists thought gene activity was relatively straightforward: Genes were transcribed into messenger RNA, which was processed and translated into the proteins of the body.   view more (2005-12-27)

Clinical trial to test stem cell approach for children with brain injury
A unique clinical trial will gauge the safety and potential of treating children suffering traumatic brain injury with stem cells derived from their own bone marrow starting early next year.   view more (2005-12-21)

Study finds overall health and quality of life intact 10 years after stem-cell transplantation
Survivors of stem-cell transplantation for blood cancers can expect to be just about as healthy 10 years later as adults who have never had a transplant, according to a new study by researchers at Fred Hutchinson Research Cancer Center.   view more (2005-09-19)

Trial at Jefferson shows new drug may help cancer patients who need stem cell transplants
A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation.   view more (2005-09-09)

Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.   view more (2005-08-02)
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