New research into the mechanisms of gene regulation
A team led by Penn State's Ross Hardison, T. Ming Chu Professor of Biochemistry and Molecular Biology, has taken a large step toward unraveling how regulatory proteins control the production of gene products during development and growth. view more (2009-11-20)
Seeing previously invisible molecules for the first time
A team of Harvard chemists led by X. Sunney Xie has developed a new microscopic technique for seeing, in color, molecules with undetectable fluorescence. view more (2009-10-26)
Compound shows potential for slowing progression of ALS
A chemical cousin of a drug currently used to treat sepsis dramatically slows the progression of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, in mice. view more (2009-10-20)
Ironing out the genetic cause of hemoglobin problems
A gene with a significant effect on regulating hemoglobin in the body has been identified as part of a genome-wide association study, which looked at the link between genes and hemoglobin level in 16,000 people. view more (2009-10-12)
Biologists ID molecular basis of high-altitude adaptation in mice
Biologists have long known how adaptive evolution works. New mutations arise within a population and those that confer some benefits to the organism increase in frequency and eventually become fixed in the population. view more (2009-08-11)
Reexamination of T. rex verifies disputed biochemical remains
A new analysis of the remains of a Tyrannosaurus rex (T. rex) that roamed Earth 68 million years ago has confirmed traces of protein from blood and bone, tendons, or cartilage. view more (2009-07-29)
Novel biomarkers in heart failure
Several new biomarkers have been recently described in Heart Failure (HF) syndrome either in stable chronic patients as in the settings of acute decompensation. view more (2009-06-01)
Researchers identify the gene responsible for a rare form of congenital anemia
The latest electronic edition of the journal Nature Genetics reports the discovery of a new gene responsible for congenital sideroblastic anemia, a rare disease, mainly characterized by the presence of ringed sideroblasts in the patients' bone marrow. view more (2009-05-11)
Light reveals breast tumor oxygen status
Light directed at a breast tumor through a needle can provide pathologists with biological specifics of the tumor and help oncologists choose treatment options that would be most effective for that individual patient. view more (2009-04-01)
Ben-Gurion U researchers -- bariatric surgery minimizes pregnancy complications for obese women
Women who undergo bariatric surgery to treat obesity will reduce the risk of medical and obstetric complications when they become pregnant, according to a study by researchers from Ben-Gurion University of the Negev's (BGU) Faculty of Health Sciences. view more (2009-03-25)
New form of intravenous iron treats anemia in chronic kidney disease patients on dialysis
Ferumoxytol, a novel intravenous form of iron that permits rapid administration of large doses, has been shown to be effective for treating iron deficiency in chronic kidney disease (CKD) patients on dialysis, according to a clinical trial appearing in the February 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN). view more (2009-01-28)
Low-carb diets prove better at controlling type 2 diabetes
In a six-month comparison of low-carb diets, one that encourages eating carbohydrates with the lowest-possible rating on the glycemic index leads to greater improvement in blood sugar control, according to Duke University Medical Center researchers. view more (2009-01-06)
The prevalence of gluten-sensitive enteropathy in iron-deficient anemia patients
Gluten sensitive enteropathy (GSE) is an autoimmune enteropathy due to food gluten intolerance in genetically predisposed people. view more (2009-01-05)
Studies examine quality of care for hospitalized sickle cell disease patients
A study assessing the quality of care for patients with sickle cell disease in a variety of hospital settings will be presented at a press conference on Saturday, December 6, at 9:30 a.m., during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA. view more (2008-12-08)
Gene therapy corrects sickle cell disease in laboratory study
Using a harmless virus to insert a corrective gene into mouse blood cells, scientists at St. Jude Children's Research Hospital have alleviated sickle cell disease pathology. view more (2008-12-04)
Researchers Shed Light on Evolution of Gene Regulation
Scientists at Penn State have shed light on some of the processes that regulate genes -- such as the processes that ensure that proteins are produced at the correct time, place, and amount in an organism -- and they also have shed light on the evolution of the DNA regions that regulate genes. view more (2008-11-25)
Preventing anemia is important to kidney disease patients' quality of life
Maintaining sufficient red blood cell levels is important to the physical and mental health of patients with chronic kidney disease (CKD), according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings indicate that preventing anemia in kidney disease patients should be an... view more... (2008-11-12)
Metabolic insight to illuminate causes of iron imbalance
New insight into key players in iron metabolism has yielded a novel tool for distinguishing among root causes of iron overload or deficiency in humans, the researchers report in the August issue of Cell Metabolism, a publication of Cell Press. While the body needs iron to produce hemoglobin, a substance in red blood cells that enables them to... view more... (2008-08-06)
Gaining ground on sickle cell disease
Although sickle cell disease is a single-gene disorder, its symptoms are highly variable. In a study published online July 14 by the Proceedings of the National Academy of Sciences, scientists at Children's Hospital Boston and the Dana Farber Cancer Institute (DFCI), in collaboration with the Broad Institute of MIT and Harvard, report five gene... view more... (2008-07-16)
Stroke study reveals key target for improving treatment and suggests that Gleevec may help
For over a decade, the drug called tPA has proven its worth as the most effective emergency treatment for the most common kind of stroke. But its promise is blemished by two facts: tPA can cause dangerous bleeding in the brain, and its brain-saving power fades fast after the third hour of a stroke. view more (2008-06-23)
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