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Research reveals molecular fingerprint of cocaine addiction
The first large-scale analysis of proteins in the brains of monkeys addicted to cocaine reveals new information on how long-term cocaine use changes the amount and activity of various proteins affecting brain function.   view more (2008-05-28)

Brain cells help neighboring nerves regenerate
Researchers have uncovered a completely unexpected way that the brain repairs nerve damage, wherein cells known as astrocytes deliver a protective protein to nearby neurons.   view more (2008-05-28)

'Intrabody' can mop up mutant protein in Huntington's disease model
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" against huntingtin, the protein whose mutant forms poison the... view more (2008-05-27)

New form of ECT is as effective as older types but without cognitive side effects
In a study appearing in the new issue of BRAIN STIMULATION, scientists report that a new form of electroconvulsive therapy (ECT) is just as effective as older forms in treating depression but without any of the cognitive side effects found in the older forms.   view more (2008-05-27)

New statistical method reveals surprises about our ancestry
A statistical approach to studying genetic variation promises to shed new light on the history of human migration.   view more (2008-05-23)

Scientists Discover a Molecular Scaffold That Guides Connections Between Brain Cells
Brain cells known as neurons process information by joining into complex networks, transmitting signals to each other across junctions called synapses. But "neurons don't just connect to other neurons," emphasizes Z. Josh Huang, Ph.D., "in a lot of cases, they connect to very... view more (2008-05-21)

Study: Patients 75 years and older with brain tumors may benefit from more aggressive treatment
A new study from University Hospitals Case Medical Center (UHCMC) finds that elderly patients - 75 years old and older-- with malignant brain tumors are not treated as aggressively as patients between 65 and 75 years old.   view more (2008-05-20)

Researchers develop first transgenic monkey model of Huntington's disease
Scientists have developed the first genetically altered monkey model that replicates some symptoms observed in patients with Huntington's disease, according to a new study funded by the National Institutes of Health.   view more (2008-05-19)

New Mount Sinai research tracks effects of addictive drugs on brain
Mount Sinai researchers may have unlocked the key to better understanding the effect addictive drugs have on the human brain.   view more (2008-05-16)

Researchers find first conclusive evidence of Alzheimer's-like brain tangles in nonhuman primates
Researchers at the Yerkes National Primate Research Center, Emory University, have discovered the first conclusive evidence of Alzheimer's-like neurofibrillary brain tangles in an aged nonhuman primate.   view more (2008-05-15)

Researchers fine-tune clot-busting treatment for bleeding in brain
A multicenter study led by Johns Hopkins doctors has fine-tuned the dosage and timing for administering clot-busting tissue plasminogen activator (tPA) to patients with strokes caused by bleeding within the brain. The treatment, as reported this week at the European Stroke Conference in Nice,... view more (2008-05-14)

Are Anxiety Disorders All in the Mind?
Using single-photon emission computed tomography (SPECT), researchers in The Netherlands were able to detect biochemical differences in the brains of individuals with generalized social anxiety disorder (also known as social phobia), providing evidence of a long-suspected biological cause for the... view more (2008-05-13)

Phantoms in the brain: Pain after amputation
Losing a limb can be a traumatic experience and, in some cases, emotional and physical pain can linger for years.   view more (2008-05-13)

Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain
Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant... view more (2008-05-12)

Scientists dig deeper into the genetics of schizophrenia by evaluating microRNAs
Researchers at Columbia University Medical Center have illuminated a window into how abnormalities in microRNAs, a family of molecules that regulate expression of numerous genes, may contribute to the behavioral and neuronal deficits associated with schizophrenia and possibly other brain disorders.   view more (2008-05-12)

Improving anxiety treatment through the help of brain imaging: A potential future treatment strategy
Wouldn't it be nice if our doctors could predict accurately whether we would respond to a particular medication" This question is important because research studies provide information about how groups of patients tend to respond to treatments, but inevitably, differences among groups of... view more (2008-05-09)

Lack of motivation in schizophrenia linked to brain chemical imbalance
A study of patients with psychotic illnesses such as schizophrenia suggests an alternative explanation for why many sufferers lack motivation. The research is described today BioMed Central's journal BMC Psychiatry.   view more (2008-05-08)

MIT study suggests caution on new anti-obesity drug in kids
Anti-obesity drugs that work by blocking brain molecules similar to those in marijuana could also interfere with neural development in young children, according to a new study from MIT's Picower Institute for Learning and Memory.   view more (2008-05-08)

Child abuse may 'mark' genes in the brains of suicide victims
A team of McGill University scientists has discovered important differences between the brains of suicide victims and so-called normal brains. Although the genetic sequence was identical in the suicide and non-suicide brains, there were differences in their epigenetic marking - a chemical coating... view more (2008-05-07)

New target for Alzheimer's disease identified
Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed.   view more (2008-05-07)

Researchers report the cloning of a key group of human genes, the protein kinases
Although the human genome has been sequenced, research into mechanism of action of genes has been hampered by the fact that most human genes have not been isolated. This is true for even the most common class of cancer-associated genes, the protein kinases, which mediate the majority of signaling... view more (2008-05-05)

Analysis of alcoholics' brains suggests treatment target
An analysis of brain tissue samples from chronic alcoholics reveals changes that occur at the molecular level in alcohol abuse - and suggests a potential treatment target, according to researchers from Wake Forest University School of Medicine.   view more (2008-05-05)

Decoding the dictionary: Study suggests lexicon evolved to fit in the brain
The latest edition of the Oxford English Dictionary boasts 22,000 pages of definitions. While that may seem far from succinct, new research suggests the reference manual is meticulously organized to be as concise as possible - a format that mirrors the way our brains make sense of and categorize... view more (2008-05-01)

It's a unisex brain with specific signals that trigger 'male' behavior
Research by Yale scientists shows that males and females have essentially unisex brains - at least in flies - according to a recent report in Cell designed to identify factors that are responsible for sex differences in behavior.   view more (2008-05-01)

Salk study links diabetes and Alzheimer's disease
Diabetic individuals have a significantly higher risk of developing Alzheimer's disease but the molecular connection between the two remains unexplained. Now, researchers at the Salk Institute for Biological Studies identified the probable molecular basis for the diabetes - Alzheimer's interaction.   view more (2008-05-01)
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