Recent Hypermethylation Current Events | Hypermethylation News
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Genes signal late-stage laryngeal cancer, poorer outcome
Researchers at Henry Ford Hospital have identified tumor-suppressing genes that may provide a more accurate diagnosis of disease stage and survival for laryngeal cancer patients than current standards. view more (2009-10-08)
Study finds 231 new genes associated with head and neck cancer
A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States. view more (2009-10-05)
DKK-3 and WIF-1: Proteins related to liver cancer development?
Liver cancer is one of the most fatal human malignancies and the third most frequent cause of tumor-related death, about half a million people globally each year. view more (2009-06-15)
A breakthrough in gastric carcinogenesis
Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. view more (2009-06-12)
Genetic Changes Outside Nuclear DNA Suspected to Trigger More Than Half of All Cancers
A buildup of chemical bonds on certain cancer-promoting genes, a process known as hypermethylation, is widely known to render cells cancerous by disrupting biological brakes on runaway growth. Now, Johns Hopkins scientists say the reverse process - demethylation - which wipes off those chemical bonds may also trigger more than half of all cancers. view more (2009-03-24)
New technique for cancer screening
Current research suggests that a new technique to determine tumor methylation status can be used in archived tissue samples. view more (2009-02-24)
In lung cancer, silencing one crucial gene disrupts normal functioning of genome
While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. view more (2009-01-05)
'Smothered' genes combine with mutations to yield poor outcome in cancer patients
Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients. view more (2008-07-16)
NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis. view more (2008-03-27)
'Swish-and-spit' test accurate for cancer
A morning gargle could someday be more than a breath freshener - it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers. view more (2008-01-02)
DNA methylation shown to promote development of colon tumors
Damaged or defective genes have long been known to be the cause of some cancers. Over the past decade, however, scientists have discovered that even healthy genes can be switched on or off and can cause cancer without any changes in the underlying DNA sequence-although how this happens has remained poorly understood. view more (2007-12-03)
Liver cancer marker could yield blood test for early detection
In the face of an emerging liver cancer crisis in Asia, researchers at the Chinese University of Hong Kong have developed a test that could help millions. view more (2007-09-18)
Effect on Breast Tumors of DNA Alternations in 3 Genes Described
Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation. view more (2007-05-17)
Study links breast cancer risk to epigenetic changes related to race, smoking and birth size
Women can encounter environmental factors that increase their risk of breast cancer at various periods of their physical development, beginning before birth and extending until menopause. view more (2007-04-16)
Researchers find better prostate cancer indicators
Researchers at Mayo Clinic have narrowed the search for effective prostate cancer biomarkers (genetic variations that point to a specific disease or condition), identifying changes in the expression of genes of the whole genome closely correlated to prostate cancer development and progression. view more (2006-03-28)
Chemoradioimmunotherapy for advanced breast cancer: hope for the future?
Innsbruck, Austria: A successful, and novel, technique to kill metastatic breast cancer cells by circumventing their chemo- and radioresistant mechanisms was by presented by Dr John Giannios, Head of Radiotherapeutic Cancer Research at the IASO Hospital, Athens, Greece at the 18th Meeting of the European Association for Cancer Research today... view more... (2004-07-06)
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