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Understanding how oxidative stress impairs endothelial progenitor cell function
Although its been over a decade since endothelial progenitor cells or EPCs, cells that circulate in the blood repairing and replacing the cells that line blood vessels, were identified, the field is still evolving.   view more (2008-11-26)

Kidney function discovery sheds light on genetic complexity of disease
To find a cure for cancer, haemophilia and other diseases, researchers need to be looking for complex, interacting genetic factors, according to the authors of a new study.   view more (2008-11-26)

Scientists Present 'Moving' Theory Behind Bacterial Decision-Making
Biochemists at North Carolina State University have answered a fundamental question of how important bacterial proteins make life-and-death decisions that allow them to function, a finding that could provide a new target for drugs to disrupt bacterial decision-making processes and related diseases.   view more (2008-11-25)

Very low birth weight is a risk factor for 1 cause of CKD
Individuals who were underweight at birth are at increased risk of developing a condition called secondary focal segmental glomerulosclerosis, according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN).   view more (2008-11-20)

Surgeons perform world's first pediatric robotic bladder reconstruction
A 10-year-old Chicago girl born with an abnormally small bladder that made her incontinent has become the first patient to benefit from a new robotic-assisted bladder-reconstruction method developed by surgeons at the University of Chicago Medical Center.   view more (2008-11-20)

Home-based diet and exercise intervention improves elderly cancer survivors' physical function
A home-based program to improve exercise and diet led to significant, clinically meaningful improvement in body weight and physical function among older long-term cancer survivors in preliminary findings from the RENEW (Reach-out to ENhancE Wellness) trial.   view more (2008-11-19)

Preventing anemia is important to kidney disease patients' quality of life
Maintaining sufficient red blood cell levels is important to the physical and mental health of patients with chronic kidney disease (CKD), according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings indicate that... view more (2008-11-12)

NC State finds new nanomaterial could be breakthrough for implantable medical devices
A team of researchers led by North Carolina State University has made a breakthrough that could lead to new dialysis devices and a host of other revolutionary medical implants.   view more (2008-11-11)

Interaction between gene variants may alter brain function in schizophrenia
A collaborative study led by investigators from Massachusetts General Hospital (MGH) is giving what may be the first look at how interactions between genes underlie a key symptom of schizophrenia, impaired working memory.   view more (2008-11-10)

Protein identified that turns off HIV-fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing... view more (2008-11-10)

Penn Scientists Map Molecular Regulation of Fat-Cell Genetics
A research team led by Mitchell Lazar, MD, PhD, Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has used state-of-the-art genetic technology to map thousands of positions where a molecular "master regulator" of fat-cell... view more (2008-11-05)

What's the influence of laxative agents on mucosal barrier repair?
The prostone lubiprostone has been shown to stimulate chloride secretion via one of the minor intestinal epithelial channels, ClC-2. This results in sustained low-level secretion of water into the lumen.   view more (2008-11-03)

African-American Canadians who receive kidney transplants fare better than those in US
African American kidney disease patients in both Canada and the United States are less likely than Caucasian Americans to have access to kidney transplants, but only African-Americans in the United States have worse health outcomes than Caucasians after a transplant is performed.   view more (2008-10-30)

Scientists identify cell changes leading to impaired 'artificial kidney' function
Molecular targets identified by a Spanish research team may hold the key to freedom for some sufferers of kidney disease. A new study published in Disease Models & Mechanisms (DMM), dmm.biologists.org, reveals the cellular signals which cause one treatment for kidney failure to lose its... view more (2008-10-28)

Even mild sleep apnea increases cardiovascular risk
People with even minimally symptomatic obstructive sleep apnea (OSA) may be at increased risk for cardiovascular disease because of impaired endothelial function and increased arterial stiffness, according to a study from the Oxford Centre for Respiratory Medicine in the UK.   view more (2008-10-27)

The Marine Mammal Center begins new leptospirosis study in California
The Marine Mammal Center is seeing a large number of leptospirosis cases in California sea lions this year and is leading a study to determine when and why the sea lions contract this disease.   view more (2008-10-23)

What is the function of NOD2 in colonic epithelial cells?
NOD2 is a cytosolic pattern recognition receptor similar in structure and function to Toll like receptors (TLRs). It can recognize and respond to a component found in the cell wall of bacteria, muramyl dipeptide (MDP), and has been shown to play an important role in the innate immune response of... view more (2008-10-23)

Study Shows Steroid Therapies Following Transplant Can Be Eliminated
A new study by researchers at UC shows that using modern immunosuppressive drugs eliminates the need for steroid therapy as early as seven days following a transplant surgery while still maintaining kidney function   view more (2008-10-22)

Researchers propose new ultrasound screening criteria for diagnosing polycystic kidney disease
Modification of the current screening criteria are needed for diagnosing patients with autosomal dominant polycystic disease (ADPKD), according to a study appearing in the January 2009 issue of the Journal of the American Society Nephrology (JASN). The results suggest that some patients with a... view more (2008-10-22)

Hypertension disparity linked to environment
Social environment may play a greater role in the disparity between the numbers of African Americans living with hypertension compared to non-Hispanic whites with the disease.   view more (2008-10-21)

Link possible between pet food contamination and baby formula contamination
A study published in the November issue of a scientific journal, Toxicological Sciences, which is published by Oxford Journals on behalf of the Society of Toxicology, describes the kidney toxicity of melamine and cyanuric acid based on research that was done to characterize the toxicity of the... view more (2008-10-16)

Brain structure provides key to unraveling function of bizarre dinosaur crests
Paleontologists have long debated the function of the strange, bony crests on the heads of the duck-billed dinosaurs known as lambeosaurs. The structures contain incredibly long, convoluted nasal passages that loop up over the tops of their skulls.   view more (2008-10-16)

Larger labs report kidney function routinely
Labs that conduct the highest number of routine blood tests are more likely than others to report estimated glomerular filtration rate (eGFR), an important measure of kidney function that can identify early kidney disease.   view more (2008-10-15)

Late-breaking results of clinical trial on therapeutic endovascular cooling reported at TCT 2008
Late-breaking results from the COOL RCN (COOLing to Prevent Radio Contrast Nephropathy in Patients Undergoing Diagnostic or Interventional Catheterization) Trial were presented during the 20th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the... view more (2008-10-15)

Embryonic heart exhibits impressive regenerative capacity
A new study demonstrates that the embryonic mouse heart has an astounding capacity to regenerate, a phenomenon previously observed only in non-mammalian species.   view more (2008-10-14)
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