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Study shows direct link between leptin and obesity-related cardiovascular disease
Obese people who don't have high cholesterol or diabetes might think they're healthy - despite the extra pounds.   view more (2008-11-11)

Fructose Sets Table For Weight Gain Without Warning
Eating too much fructose can induce leptin resistance, a condition that can easily lead to becoming overweight when combined with a high-fat, high-calorie diet, according to a new study with rats.   view more (2008-10-16)

Newly identified cells make fat
To understand where fat comes from, you have to start with a skinny mouse. By using such a creature, and observing the growth of fat after injections of different kinds of immature cells, scientists at the Howard Hughes Medical Institute and Rockefeller University have discovered an important fat... view more (2008-10-06)

Low levels of brain chemical may lead to obesity, NIH study of rare disorder shows
A brain chemical that plays a role in long term memory also appears to be involved in regulating how much people eat and their likelihood of becoming obese, according to a National Institutes of Health study of a rare genetic condition.   view more (2008-08-28)

Scientists discover leptin can also aid type 1 diabetics
Terminally ill rodents with type 1 diabetes have been restored to full health with a single injection of a substance other than insulin by scientists at UT Southwestern Medical Center.   view more (2008-08-26)

Study shows that surgical weight loss does not eliminate obstructive sleep apnea
A study in the August 15 issue of the Journal of Clinical Sleep Medicine shows that surgical weight loss results in an improvement of obstructive sleep apnea (OSA), but most patients continue to have moderate to severe OSA one year after undergoing bariatric surgery.   view more (2008-08-15)

Battle of the bulge: Low leptin levels undermine successful weight loss
Individuals who are obese are at increased risk of many diseases, including type 2 diabetes and heart disease. As 75%-95% of previously obese individuals regain their lost weight, many researchers are interested in developing treatments to help individuals maintain their weight loss.   view more (2008-06-23)

Common cooking spice shows promise in combating diabetes and obesity
Turmeric, an Asian spice found in many curries, has a long history of use in reducing inflammation, healing wounds and relieving pain, but can it prevent diabetes?   view more (2008-06-23)

Combining exercise with hormone could prevent weight gain
Once heralded as a promising obesity treatment, the hormone leptin lost its fat-fighting luster when scientists discovered overweight patients were resistant to its effects. But pairing leptin with just a minor amount of exercise seems to revive the hormone's ability to fight fat again, University... view more (2008-05-28)

Mapping the genetic locus for triglycerides
Researchers have mapped out a region on human chromosome 1 that contributes to genetically elevated blood triglyceride levels, a major risk factor for heart disease.   view more (2008-04-28)

Normal weight obesity: An emerging risk factor for heart and metabolic problems
More than half of American adults considered to have normal body weight in America have high body fat percentages -- greater than 20 percent for men and 30 percent for women -- as well as heart and metabolic disturbances, new Mayo Clinic research shows.   view more (2008-03-28)

Body Mass Index may serve as prognostic tool for advanced, aggressive breast cancers
Body Mass Index (BMI), the measure of a person's fat based on their height and weight, may be an effective prognostic tool for specific types of breast cancer, according to research from The University of Texas M. D. Anderson Cancer Center.   view more (2008-03-14)

Rare syndrome provides clues on obesity, blood pressure
University of Iowa researchers have found a clue about how resistance to the hormone leptin might disrupt the brain signals that tell the body when to stop eating.   view more (2008-03-04)

MSU researchers make new discoveries on what does and doesn't affect immune system
Scientists know that a number of factors can affect the body's immune system: poor diet, certain steroids, chronic stress. Now researchers at Michigan State University have discovered that an appetite-controlling hormone also affects the immune system, while natural versions of certain steroids do... view more (2008-02-05)

Adaptive functional evolution of leptin in cold-adaptive pika family
Researchers at the Northwest Institute of Plateau Biology, Chinese Academy of Sciences have put forward the viewpoint for the first time that adaptive functional evolution may occur in the leptin protein of the pika (Ochotona) family, a typical cold-adaptive mammal.   view more (2008-01-23)

Mom's obesity during conception phase may set the stage for offspring's obesity risk
The number of overweight and obese Americans continues to grow rapidly. Today, 50 percent of adults are overweight and up to 20 percent are obese. While the number of overweight/obese children is at an all time high, the steady increase of overweight infants -- individuals under 11 months old -- is... view more (2008-01-04)

Predicting growth hormone treatment success
Growth hormone treatments work better on some children than on others, but judging which candidates will gain those vital inches in height is no simple task.   view more (2007-12-13)

Obesity reduces chances of spontaneous pregnancy in women who are subfertile but ovulating normally
A new study of obesity and the probability of pregnancy has shown that a woman's chances of a spontaneous pregnancy steadily decrease the fatter she is.   view more (2007-12-12)

Brain circuits that control hunger identified
Researchers at UCLA have determined the brain circuits involved in hunger that are influenced by a hormone called leptin. In previous clinical trials, supplementation of leptin, the signaling molecule produced by fat cells, produced moderate weight loss in some obese patients, purportedly by... view more (2007-10-30)

Obesity-related hormone is higher in children with Down syndrome
Children with Down syndrome are more likely than their unaffected siblings to have higher levels of a hormone associated with obesity, according to pediatric researchers.   view more (2007-10-29)

Joslin researchers uncover potential role of leptin in diabetes
A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion.   view more (2007-10-02)

Brain system serves as 'remote control' for fat metabolism
A system in the brain already known to regulate food intake also serves as a direct "remote control" for the way fat is stored and metabolized in the body, say University of Cincinnati (UC) researchers.   view more (2007-09-21)

Circulating fats kill transplanted pancreas cells, study shows
Dietary restrictions or other strategies that limit fat formation might make pancreatic cell transplants more effective, UT Southwestern Medical Center researchers report.   view more (2007-08-28)

Despite overeating, morbidly obese mice gain protection against diabetes
The "world's fattest mice" can overeat without developing insulin resistance or diabetes thanks to a glut of a key hormone, a dichotomy that helps explain why not all obese people are diabetic, a UT Southwestern Medical Center researcher has found.   view more (2007-08-24)

Research shows skeleton to be endocrine organ
Bones are typically thought of as calcified, inert structures, but researchers at Columbia University Medical Center have now identified a surprising and critically important novel function of the skeleton.   view more (2007-08-10)
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