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Study shows hormone replacement therapy decreases mortality in younger postmenopausal woman
Hormone replacement therapy (HRT) to treat menopausal estrogen deficiency has been in widespread use for over 60 years. Several observational studies over the years showed that HRT use by younger postmenopausal women was associated with a significant reduction in total mortality; available evidence supported the routine use of HRT to increase... view more... (2009-10-29)

LSUHSC's England plays key role in developing new ALS treatment guidelines
Dr. John England, Professor and Chairman of Neurology at LSU Health Sciences Center New Orleans, analyzed research findings and was responsible for the quality and accuracy of evidence analysis and the conclusions of the studies resulting in new guidelines for treating Lou Gehrig's disease, or amyotropic lateral sclerosis (ALS).   view more (2009-10-13)

NIH launches 2009 H1N1 influenza vaccine trials in HIV-infected pregnant women
The first clinical trials to test whether the 2009 H1N1 influenza vaccine can safely elicit a protective immune response in pregnant women launched yesterday, and a trial to conduct the same test in HIV-infected children and youth will begin next week.   view more (2009-10-12)

New aging studies improving vaccine efficacy for the elderly
A new study from the Trudeau Institute in Saranac Lake, New York, demonstrates that immune system cells important for both pathogen resistance and vaccine efficacy live longer in older animals but because of this longevity acquire functional defects.   view more (2009-10-06)

Baumann Lab demonstrates role of protein in distinguishing chromosome ends from DNA breaks
The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer.   view more (2009-09-18)

The disease markers that will aid arthritis research
A combination of biochemical and MRI markers will allow improved measurement of osteoarthritis (OA) progression.   view more (2009-07-24)

Bad mitochondria may actually be good for you
Mice with a defective mitochondrial protein called MCLK1 produce elevated amounts of reactive oxygen when young; that should spell disaster, yet according to a study in this week's JBC these mice actually age at a slower rate and live longer than normal mice.   view more (2009-07-23)

New NIH Funding to Support UAB Total Joint Replacement Research Collaboration
Newly announced National Institutes of Health (NIH) funding will expand the reach of ongoing University of Alabama at Birmingham (UAB) research into a unique nanostructured coating to improve the performance and longevity of total joint replacement components.   view more (2009-07-17)

Children's Hospital of Pittsburgh of UPMC scientists identify enzyme important in aging
The secret to longevity may lie in an enzyme with the ability to promote a robust immune system into old age by maintaining the function of the thymus throughout life, according to researchers studying an "anti-aging" mouse model that lives longer than a typical mouse.   view more (2009-07-13)

Operation for aneurysm yields nearly normal longevity
Preventive operations are being used more and more often to treat abdominal aortic aneurysms.   view more (2009-07-08)

Scientists find a biological 'fountain of youth' in new world bat caves
Scientists from Texas are batty over a new discovery which could lead to the single most important medical breakthrough in human history-significantly longer lifespans.   view more (2009-07-01)

Longer life linked to specific foods in Mediterranean diet
Some food groups in the Mediterranean diet are more important than others in promoting health and longer life.   view more (2009-06-24)

Researchers To Reveal Aging's Origins on Global Stage
Four of the biologists who described the underlying causes of aging will soon share their findings with an international audience during a symposium at the upcoming World Congress of Gerontology and Geriatrics.   view more (2009-06-24)

Report identifies early childhood conditions that lead to adult health disparities
The origins of many adult diseases can be traced to early negative experiences associated with social class and other markers of disadvantage.   view more (2009-06-03)

Role for CISD2 gene in human disease and lifespan control
In the May 15th issue of G&D, Dr. Ting-Fen Tsai (The National Yang-Ming University, Taiwan) and colleagues present a new animal model of human Wolfram Syndrome, and effectively link CISD2 gene function, mitochondrial integrity and aging in mammals.   view more (2009-05-15)

30-year follow-up study: 'Tremendous' impact of smoking on mortality and cardiovascular disease
Non-smokers live longer and have less cardiovascular disease than those who smoke, according to a 30-year follow-up study of 54,000 men and women in Norway.   view more (2009-05-08)

Late motherhood boosts family lifespan
Women who have babies naturally in their 40s or 50s tend to live longer than other women.   view more (2009-05-04)

SIRT1 takes down tumors
Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division.   view more (2009-04-13)

Researchers identify personality traits
Researchers from Boston University School of Medicine's (BUSM) New England Centenarian Study have noted specific personality traits associated with healthy aging and longevity amongst the children of centenarians.   view more (2009-04-06)

Starve a yeast, sweeten its lifespan
Johns Hopkins researchers have discovered a new energy-making biochemical twist in determining the lifespan of yeast cells, one so valuable to longevity that it is likely to also functions in humans.   view more (2009-03-24)
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