Saliva proteins change as women age
In a step toward using human saliva to tell whether those stiff joints, memory lapses, and other telltale signs of aging are normal or red flags for disease, scientists are describing how the protein content of women's saliva change with advancing age. view more (2009-11-19)
Smokers with common autoimmune disorder at higher risk for skin damage
As if there weren't enough reasons to stop smoking, a team of researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) have just found another. view more (2009-11-03)
Kidney transplants generally safe for lupus patients
Individuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. view more (2009-11-02)
Iberian wolves prefer wild roe deer to domestic animals
A Spanish researcher has analysed the preferences of wolves from the north east of the Iberian Peninsula to demonstrate that, in reality, their favourite prey are roe deer, deer and wild boar, ahead of domestic ruminants (sheep, goats, cows and horses). view more (2009-10-26)
Lupus patients perceive benefit from cardiovascular disease prevention counseling program
According to a new study by Hospital for Special Surgery investigators presented at the American College of Rheumatology meeting on October 21 in Philadelphia, most lupus patients are not aware that their condition puts them at a higher risk for cardiovascular disease and a counseling program is a valuable way to promote education and lifestyle... view more... (2009-10-19)
Stanford study identifies cellular mechanism that causes lupuslike symptoms in mice
Macrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease. view more (2009-10-19)
National report shines light on lupus 50-year treatment drought
Today, The Lewin Group, a national health care consulting firm, issued recommendations on ways to overcome the barriers that have obstructed lupus drug development resulting in no new drug approval for this disease in more than 50 years - since the Eisenhower Administration. view more (2009-10-05)
Scripps research scientists find key culprits in lupus
The more than 1.5 million Americans with systemic lupus erythematosus (or lupus) suffer from a variety of symptoms that flare and subside, often including painful or swollen joints, extreme fatigue, skin rashes, fever, and kidney problems. view more (2009-06-30)
Psoriasis associated with cardiovascular disease and increased mortality
The skin disease psoriasis is associated with atherosclerosis (a buildup of plaque in the arteries) characterized by an increased prevalence of ischemic heart disease, cerebrovascular disease, peripheral artery disease and an increased risk of death. view more (2009-06-16)
Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models
DNA vaccination using lupus autoantigens and interleukin-10 (IL-10, a cytokine that plays an important role in regulating the immune system) has potential as a novel therapy to induce antigen specific tolerance and may help to prevent kidney damage in patients with systemic lupus erythematosus (SLE). view more (2009-06-12)
Anxiety and depression lower quality of life in majority of systemic lupus erythematosus patients
92.8% of patients with systemic lupus erythematosus (SLE) suffer anxiety and depression which significantly affects both their physical and emotional quality of life (QoL). view more (2009-06-12)
Development of DNA drugs gives hope to lupus patients
A generation of DNA-like compounds, class R inhibitory oligonucleotides (INH-ODNs), have been shown to effectively inhibit cells responsible for the chronic autoimmune condition lupus. view more (2009-05-28)
Team develops DNA compounds that could help treat lupus
A research team led by a University of Iowa investigator has generated DNA-like compounds that effectively inhibit the cells responsible for systemic lupus erythematosus -- the most common and serious form of lupus. view more (2009-05-28)
Popular cancer drug linked to often fatal brain virus
The 57-year-old lawyer in New York had handily completed the New York Times' Saturday crossword puzzle - the hardest of the week - for years. But one Saturday morning, suddenly he couldn't retrieve the words to fill in the squares. view more (2009-05-19)
Potential preventative therapy for Type 1 diabetes
Scientists believe they may have found a preventative therapy for Type 1 diabetes, by making the body's killer immune cells tolerate the insulin-producing cells they would normally attack and destroy, prior to disease onset. view more (2009-04-29)
Understanding a target of quinoline drugs
The full details about the molecules and mechanisms that underlie the development of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, remain to be discovered. view more (2009-04-28)
UT Southwestern researchers probe kidney damage, protection in lupus
Kidney damage associated with the autoimmune disease lupus is linked to a malfunction of immune cells that causes them to congregate in and attack the organs, researchers at UT Southwestern Medical Center have discovered in a mouse study. view more (2009-04-21)
Gene linked to lupus might explain gender difference in disease risk
In an international human genetic study, researchers at UT Southwestern Medical Center have identified a gene linked to the autoimmune disease lupus, and its location on the X chromosome might help explain why females are 10 times more susceptible to the disease than males. view more (2009-03-30)
Fireflies and jellyfish help illuminate quest for cause of infertility
Genes taken from fireflies and jellyfish are literally shedding light on possible causes of infertility and autoimmune diseases in humans. view more (2009-03-27)
Stopping autoimmunity before it strikes
Current research describes a new method to track the development of autoimmune diseases before the onset of symptoms. The related report by Zangani et al, "Tracking early autoimmune disease by bioluminescent imaging of NF-κB activation reveals pathology in multiple organ systems," appears in the April 2009 issue of The American... view more... (2009-03-25)
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