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Apelin to rescue diabetics
Sugar is naturally present in the blood in the form of glucose and is stored in the liver or adipose tissue (fat) thanks to the action of insulin. Glucose is stored or directly used to ensure satisfactory function of the heart, brain and so on according to the body's demands.   view more (2008-11-05)

Gene against bacterial attack unravelled
Dutch researcher Joost Wiersinga from AMC Medical Centre in Amsterdam has unravelled a genetic defence mechanism against the lethal bacteria Burkholderia pseudomallei. The research is the next step towards a vaccine against this bacterium suitable for bioweapons.   view more (2008-10-29)

New cell division mechanism discovered
A novel cell division mechanism has been discovered in a microorganism that thrives in hot acid. The finding may also result in insights into key processes in human cells, and in a better understanding of the main evolutionary lineages of life on Earth.   view more (2008-10-28)

Mechanism in cells that generate malignant brain tumors may offer target for gene therapy
Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development of these cells from which malignant brain tumors may originate.   view more (2008-10-27)

Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
Researchers from Uppsala University have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in today's on-line issue of Molecular Cell, have implications in understanding the human disorder Beckwith-Wiedemann syndrome.   view more (2008-10-27)

Birth control has long-term effect on hormone exposure
Researchers at Wake Forest University School of Medicine may be one step closer to understanding why past oral contraceptive use dramatically lowers the risk of ovarian and uterine cancers later in life.   view more (2008-10-21)

Rong Li Lab probes mechanism of asymmetry in meiotic cell division
The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the team discovered that chromosomes can recruit to their vicinity a protein called formin-2.   view more (2008-10-08)

An effective strategy for inhibition of cirrhosis
In China, the incidence of liver cirrhosis is still high, although new therapeutic approaches have recently been proposed, there is no established therapy for liver fibrosis, and Authors investigated the prevention effects of Chinese Medicine Qianggan-Rongxian Soup on liver fibrosis induced by DMN... view more (2008-09-25)

Pneumatosis cystoids intestinalis after fluorouracil chemotherapy
The mechanism of pneumatosis cystoids intestinalis (PCI) is unclear. The mechanical and bacterial factors are most predominant causes of PCI.   view more (2008-09-18)

New mechanism for cardiac arrhythmia discovered
It has long been thought that virus infections can cause cardiac arrhythmia. But why has not been understood. Ulrike Lisewski, Dr. Yu Shi, Michael Radke and Professor Michael Gotthardt of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now discovered the... view more (2008-09-18)

Stem cells may solve mystery of early pregnancy breast cancer protection
The answer to why an early pregnancy seems to protect against breast cancer could rest with a decrease in stem cells found after animals have given birth, said researchers at Baylor College of Medicine in a report that appears in the current issue of the journal Stem Cell.   view more (2008-09-17)

Simulations help explain fast water transport in nanotubes
By discovering the physical mechanism behind the rapid transport of water in carbon nanotubes, scientists at the University of Illinois have moved a step closer to ultra-efficient, next-generation nanofluidic devices for drug delivery, water purification and nano-manufacturing.    view more (2008-09-17)

Cortisol and fatty liver: Researchers find cause of severe metabolic disorders
A healthy body stores fat in the form of so-called triglycerides in specialized fatty tissue as an energy reserve. Under certain conditions the delicate balance of the lipid metabolism gets out of control and fat is accumulated in the liver, leading to the dreaded fatty liver.   view more (2008-09-10)

Accumulated bits of a cell's own DNA can trigger autoimmune disease
A security system wired within every cell to detect the presence of rogue viral DNA can sometimes go awry, triggering an autoimmune response to single-stranded bits of the cell's own DNA, according to a report in the August 22nd issue of the journal Cell, a Cell Press publication.   view more (2008-08-22)

Light Receptors in Eye Play Key Role in Setting Biological Clock, Study Shows
Biologists at the University of Virginia have discovered a switching mechanism in the eye that plays a key role in regulating the sleep/wake cycles in mammals.   view more (2008-08-18)

MSU's discovery of plant protein holds promise for biofuel production
Scientists at Michigan State University have identified a new protein necessary for chloroplast development. The discovery could ultimately lead to plant varieties tailored specifically for biofuel production.   view more (2008-08-18)

Sensitivity to antidepressants linked with TrkB-mediated neural proliferation
Scientists have unveiled a functional link between production of new neurons and the effectiveness of antidepressants (ADs) in an animal model. The study, published by Cell Press in the August 14 issue of the journal Neuron, provides exciting insight into a mechanism that might underlie a poor... view more (2008-08-14)

Newly discovered molecular switch helps decide cell type in early embryo development
Researchers have discovered a central molecular switch in fruit fly embryos that opens new avenues for studying the causes of birth defects and cancer in humans. Writing about their study in the Aug. 12 Developmental Cell, scientists at Cincinnati Children's Hospital Medical Center determined the... view more (2008-08-12)

New insight into most common forebrain malformation
St. Jude Children's Research Hospital scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the most common developmental malformation of the anterior brain and face in newborns,... view more (2008-08-12)

When neurons fire up: Study sheds light on rhythms of the brain
In our brains, groups of neurons fire up simultaneously for just milliseconds at a time, in random rhythms, similar to twinkling lightning bugs in our backyards. New research from neuroscientists at Indiana University and the University of Montreal provides a model -- a rhyme and reason -- for this... view more (2008-08-06)

Researchers explain odd oxygen bonding under pressure
Oxygen, the third most abundant element in the cosmos and essential to life on Earth, changes its forms dramatically under pressure transforming to a solid with spectacular colors. Eventually it becomes metallic and a superconductor.   view more (2008-08-05)

Researchers find differences in swallowing mechanism of Rett syndrome patients
Researchers at Wake Forest University Baptist Medical Center have found that the reflux and swallowing problems that are common symptoms in patients with Rett syndrome and other neurological impairments, may be caused by a different mechanism than they are in healthy individuals.   view more (2008-08-05)

Key to virulence protein entry into host cells discovered
Researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have identified the region of a large family of virulence proteins in oomycete plant pathogens that enables the proteins to enter the cells of their hosts.   view more (2008-08-05)

Fish with temperature-dependent sex determination face global warming
In vertebrates with separate sexes, sex determination can be genotypic (GSD) or temperature-dependent (TSD). TSD is very common in reptiles, where the ambient temperature during sensitive periods of early development irreversibly determines whether an individual will be male or female.   view more (2008-07-30)

Researchers discover cell's 'quality control' mechanism
Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases,... view more (2008-07-30)
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