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Experimental agent reduces breast cancer metastasis to bone
Researchers have reduced breast cancer metastasis to bone using an experimental agent to inhibit ROCK, a protein that was found to be over-expressed in metastatic breast cancer.   view more (2009-11-04)

Study sheds light on evolution of human complexity
A painstaking analysis of thousands of genes and the proteins they encode shows that human beings are biologically complex, at least in part, because of the way humans evolved to cope with redundancies arising from duplicate genes.   view more (2009-11-04)

MicroRNA-mediated metastasis suppression
Metastases are responsible for over 90% of cancer deaths. In the upcoming issue of G&D, Dr. Robert Weinberg (MIT) and colleagues lend molecular insight into how microRNAs suppress tumor metastasis.    view more (2009-10-29)

Texas A&M researchers find new mechanism for circadian rhythm
Molecules that may hold the key to new ways to fight cancer and other diseases have been found to play an important role in regulating circadian rhythm, says Liheng Shi, a researcher in Texas A&M's Department of Veterinary Integrative Biosciences.   view more (2009-10-21)

New cancer gene discovered
A new cancer gene has been discovered by a research group at the Sahlgrenska Academy. The gene causes an insidious form of glandular cancer usually in the head and neck and in women also in the breast. The discovery could lead to quicker and better diagnosis and more effective treatment.   view more (2009-10-14)

UCSF scientists illuminate how microRNAs drive tumor progression
UCSF researchers have identified collections of tiny molecules known as microRNAs that affect distinct processes critical for the progression of cancer.   view more (2009-09-17)

Lung cancer suppresses miR-200 to invade and spread
Primary lung cancer shifts to metastatic disease by suppressing a family of small molecules that normally locks the tumor in a noninvasive state, researchers at The University of Texas M. D. Anderson Cancer Center report in the Sept. 15 edition of Genes and Development.   view more (2009-09-15)

Scientists Use MicroRNAs to Track Evolutionary History for First Time
The large group of segmented worms known as annelids, which includes earthworms, leeches and bristle worms, evolved millions of years ago and can be found in every corner of the world.   view more (2009-09-10)

MicroRNAs circulating in blood show promise as biomarkers to detect pancreatic cancer
A blood test for small molecules abnormally expressed in pancreatic cancer may be a promising route to early detection of the disease.   view more (2009-09-08)

MicroRNA in human saliva may help diagnose oral cancer
Researchers continue to add to the diagnostic alphabet of saliva by identifying the presence of at least 50 microRNAs that could aid in the detection of oral cancer, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.    view more (2009-08-26)

International research team seeks to unravel flatworm regeneration
Planarian flatworms are only a few millimeters up to a few centimeters in length, live in freshwater and are the object of intense research, because they possess the extraordinary ability to regenerate lost tissue with the help of their stem cells (neoblasts) and even grow an entirely new worm out of minute amputated body parts.   view more (2009-07-21)

Gladstone scientists identify genetic factors that hold promise for treatment of vascular diseases
Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) have discovered a key switch that makes stem cells turn into the type of muscle cells that reside in the wall of blood vessels.   view more (2009-07-06)

MicroRNAs help control HIV life cycle
Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells.   view more (2009-06-26)

Mean new microRNA data analysis method gives sharper results
Our understanding of the importance of microRNAs in regulating gene expression is expanding, and with it our requirement for robust methods to measure their expression levels.   view more (2009-06-16)

RNA snippet suppresses spread of aggressive breast cancer
A low cellular level of a tiny fragment of RNA appears to increase the spread of breast cancer in mouse models of the disease, according to researchers at Whitehead Institute for Biomedical Research.   view more (2009-06-16)

MicroRNAs grease the cell's circadian clockwork
Most of our cells possess an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day.   view more (2009-06-01)

miR-196a promotes the metastases of tumors
MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by inhibition of transcription or translation of proteins.   view more (2009-05-13)

Researchers find snippet of RNA that helps make individuals remarkably alike
"No two people are alike." Yet when we consider the thousands of genes with frequent differences in genetic composition among different people, it is remarkable how much alike we are.   view more (2009-05-06)

Scientists shed light on inner workings of human embryonic stem cells
Scientists at UC Santa Barbara have made a significant discovery in understanding the way human embryonic stem cells function.   view more (2009-05-01)

Throwing the micro switch: MicroRNA may link smoking risk gene to neurobiology of addiction
During the past several years, significant progress has been made in identifying susceptibility genes for nicotine dependence through genetic linkage and association analyses.   view more (2009-04-23)
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