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Experimental agent reduces breast cancer metastasis to bone
Researchers have reduced breast cancer metastasis to bone using an experimental agent to inhibit ROCK, a protein that was found to be over-expressed in metastatic breast cancer.   view more (2009-11-04)

MicroRNA-mediated metastasis suppression
Metastases are responsible for over 90% of cancer deaths. In the upcoming issue of G&D, Dr. Robert Weinberg (MIT) and colleagues lend molecular insight into how microRNAs suppress tumor metastasis.    view more (2009-10-29)

Texas A&M researchers find new mechanism for circadian rhythm
Molecules that may hold the key to new ways to fight cancer and other diseases have been found to play an important role in regulating circadian rhythm, says Liheng Shi, a researcher in Texas A&M's Department of Veterinary Integrative Biosciences.   view more (2009-10-21)

UCSF scientists illuminate how microRNAs drive tumor progression
UCSF researchers have identified collections of tiny molecules known as microRNAs that affect distinct processes critical for the progression of cancer.   view more (2009-09-17)

Lung cancer suppresses miR-200 to invade and spread
Primary lung cancer shifts to metastatic disease by suppressing a family of small molecules that normally locks the tumor in a noninvasive state, researchers at The University of Texas M. D. Anderson Cancer Center report in the Sept. 15 edition of Genes and Development.   view more (2009-09-15)

Scientists Use MicroRNAs to Track Evolutionary History for First Time
The large group of segmented worms known as annelids, which includes earthworms, leeches and bristle worms, evolved millions of years ago and can be found in every corner of the world.   view more (2009-09-10)

MicroRNAs circulating in blood show promise as biomarkers to detect pancreatic cancer
A blood test for small molecules abnormally expressed in pancreatic cancer may be a promising route to early detection of the disease.   view more (2009-09-08)

Predicting cancer prognosis
Researchers led by Dr. Soheil Dadras at the Stanford University Medical Center have developed a novel methodology to extract microRNAs from cancer tissues.   view more (2009-08-28)

MicroRNA in human saliva may help diagnose oral cancer
Researchers continue to add to the diagnostic alphabet of saliva by identifying the presence of at least 50 microRNAs that could aid in the detection of oral cancer, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.    view more (2009-08-26)

Dental researchers confirm microRNAs as biomarkers for oral cancer detection
A new study published by researchers at the UCLA School of Dentistry substantiates the effectiveness of measuring the microRNAs present in saliva to detect oral squamous cell carcinoma.   view more (2009-08-26)

Advances in lung cancer research announced at conference
Dr. Glen Weiss of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare this week announced two significant advances in treating lung cancer at an international cancer research conference.    view more (2009-08-10)

International research team seeks to unravel flatworm regeneration
Planarian flatworms are only a few millimeters up to a few centimeters in length, live in freshwater and are the object of intense research, because they possess the extraordinary ability to regenerate lost tissue with the help of their stem cells (neoblasts) and even grow an entirely new worm out of minute amputated body parts.   view more (2009-07-21)

Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels
A newly discovered mechanism controls whether muscle cells in blood vessels hasten the development of both atherosclerosis and Alzheimer's disease, according to an article published online today in the journal Nature.   view more (2009-07-06)

Gladstone scientists identify genetic factors that hold promise for treatment of vascular diseases
Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) have discovered a key switch that makes stem cells turn into the type of muscle cells that reside in the wall of blood vessels.   view more (2009-07-06)

MicroRNAs help control HIV life cycle
Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells.   view more (2009-06-26)

Cancer researchers link DICER1 gene mutation to rare childhood cancer
Research published today in Science Express from the journal Science demonstrates the first definitive link between mutations in the gene DICER1 and cancer.   view more (2009-06-26)

Research uncovers clues to virus-cancer link
In a series of recently-published articles, a research team from the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients.   view more (2009-06-18)

Mean new microRNA data analysis method gives sharper results
Our understanding of the importance of microRNAs in regulating gene expression is expanding, and with it our requirement for robust methods to measure their expression levels.   view more (2009-06-16)

RNA snippet suppresses spread of aggressive breast cancer
A low cellular level of a tiny fragment of RNA appears to increase the spread of breast cancer in mouse models of the disease, according to researchers at Whitehead Institute for Biomedical Research.   view more (2009-06-16)

Stem cell protein offers a new cancer target
A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children's Hospital Boston.   view more (2009-06-02)
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