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Recent Molecular Biology Current Events | Molecular Biology News | 6

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Key protein regulating inflammation may prove relevant to controlling sepsis
Scientists at Singapore's Institute of Molecular and Cell Biology (IMCB), under the Agency for Science, Technology and Research (A*STAR), have identified the protein, WIP1, as the molecular "brake" that curbs severe inflammation in the body.   view more (2009-05-15)

How an enzyme tells stem cells which way to divide
Driving Miranda, a protein in fruit flies crucial to switch a stem cell's fate, is not as complex as biologists thought, according to University of Oregon biochemists. They've found that one enzyme (aPKC) stands alone and acts as a traffic cop that directs which roads daughter cells will take.   view more (2009-05-14)

Visualizing virus replication in 3 dimensions
Dengue fever is the most common infectious disease transmitted by mosquitoes - some 100 million people around the world are infected. Researchers at the Hygiene Institute at Heidelberg University Hospital were the first to present a three-dimensional model of the location in the human cell where the virus is reproduced.   view more (2009-05-08)

New universal breast cancer marker predicts recurrence and clinical outcome
Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, predicting early disease recurrence, metastasis and breast cancer patient survival.   view more (2009-05-07)

Stowers Researchers Develop Whole Genome Sequencing Approach for Mutation Discovery
The Stowers Institute's Hawley Lab and Molecular Biology Facility have developed a "whole-genome sequencing approach" to mapping mutations in fruit flies.   view more (2009-05-06)

Researchers find snippet of RNA that helps make individuals remarkably alike
"No two people are alike." Yet when we consider the thousands of genes with frequent differences in genetic composition among different people, it is remarkable how much alike we are.   view more (2009-05-06)

Shilatifard and colleagues clarify the enzymatic activity of factors involved in childhood leukemia
The Stowers Institute's Shilatifard Lab and colleagues have provided new insight into the molecular basis for H3K4 methylation, an activity associated with the MLL protein found in chromosomal translocation-based aggressive infant acute leukemias.   view more (2009-05-05)

ISU researcher identifies key function in protein, cell transcription
When cells decide to make proteins, key building blocks of all organisms, they need to know where to start reading the instructions for assembling them.    view more (2009-05-04)

Finding Will Improve Accuracy of Cancer Diagnosis
Van Andel Research Institute (VARI) investigators working in collaboration with Cleveland Clinic researchers have determined that two types of kidney tumors previously thought to be different diseases are actually variations of the same disease.   view more (2009-04-30)

Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma
If you're one of the millions who dread the spring allergy season, things are looking up.   view more (2009-04-30)

Toward a systems biology map of iron metabolism
Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism.   view more (2009-04-29)

Nanoneedle is small in size, but huge in applications
Researchers at the University of Illinois have developed a membrane-penetrating nanoneedle for the targeted delivery of one or more molecules into the cytoplasm or the nucleus of living cells.   view more (2009-04-29)

Analysis finds strong match between molecular, fossil data in evolutionary studies
During a seminar at another institution several years ago, University of Chicago paleontologist David Jablonski fielded a hostile question: Why bother classifying organisms according to their physical appearance, let alone analyze their evolutionary dynamics, when molecular techniques had already invalidated that approach?   view more (2009-04-29)

Understanding a target of quinoline drugs
The full details about the molecules and mechanisms that underlie the development of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, remain to be discovered.   view more (2009-04-28)

Using combinatorial libraries to engineer genetic circuits advances synthetic biology
Streamlining the construction of synthetic gene networks has led a team of Boston University researchers to develop a technique that couples libraries of diversified components with computer modeling to guide predictable gene network construction without the back and forth tweaking.   view more (2009-04-23)

New advances in cancer research to be highlighted at University of Leicester
A scientist whose work is key to understanding how cancer cells divide and spread in the body is to present advances in his latest research at a public forum to be held at the University of Leicester.   view more (2009-04-22)

Major international study challenges notions of how genes are controlled in mammals
Scientists at the Omics Science Center (OSC) of the RIKEN Yokohama Institute in Japan -- along with researchers from McGill University and other institutions worldwide -- are challenging current notions of how genes are controlled in mammals.   view more (2009-04-22)

Mouse model provides a new tool for investigators of human developmental disorder
Wolf-Hirschhorn Syndrome (WHS) is a human disease caused by spontaneous genetic deletions. Children born with WHS have a characteristic set of facial features, including a wide flat nose bridge, downturned mouth, high forehead, and highly arched eyebrows.   view more (2009-04-21)

TGen researchers discover possible way to block the spread of deadly brain tumors
Researchers at the Translational Genomics Research Institute (TGen) may have found a way to stop the often-rapid spread of deadly brain tumors.   view more (2009-04-20)

Personalized medicine helps cancer patients survive
Cancer patients can survive longer under treatments based on their individual genetic profiles, according to a nationwide study released jointly today by Phoenix-area healthcare organizations.   view more (2009-04-20)
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