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Researchers identify ALS gene mutation
Research that has discovered a new gene whose mutations cause 5 percent of inherited cases of ALS (amyotrophic lateral sclerosis) is part of a national study led by the Northwestern University Feinberg School of Medicine. view more (2009-02-27)
Self-digestion as a means of survival
In times of starvation, cells tighten their belts: they start to digest their own proteins and cellular organs. The process - known as autophagy - takes place in special organelles called autophagosomes. view more (2009-02-27)
New models question old assumptions about how many molecules it takes to control cell division
A single cell - whether a yeast cell or one of your cells - is exquisitely sensitive to its surroundings. It receives input signals, processes the information, makes decisions, and issues commands for making the proper response. view more (2009-02-25)
Cholesterol-reducing drugs may lessen brain function, says ISU researcher
Research by an Iowa State University scientist suggests that cholesterol-reducing drugs known as statins may lessen brain function. view more (2009-02-24)
Online collaboration identifies bacteria
A new website has been launched which allows scientists everywhere to collaborate on the identification of bacterial strains. This new resource, described in the open access journal BMC Biology, provides a portal for electronic bacterial taxonomy. view more (2009-02-19)
Structural polymorphism of 441-residue Tau at single residue resolution
Worldwide almost 30 million suffer from Alzheimer's disease, an irreversible, neurodegenerative condition that is eventually fatal. view more (2009-02-17)
Groundbreaking study on complex movements of enzymes
A groundbreaking study has revealed in great detail how enzymes in the cell cooperate to make fat. These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs. view more (2009-02-12)
Diverse 'connectomes' hint at genes' limits in the nervous system
Genetics may play a surprisingly small role in determining the precise wiring of the mammalian nervous system, according to painstaking mapping of every neuron projecting to a small muscle mice use to move their ears. view more (2009-02-10)
Biologists solve mystery of black wolves
Why do nearly half of North American wolves have black coats while European wolves are overwhelmingly gray or white? The surprising answer, according to teams of biologists and molecular geneticists from Stanford University, UCLA, Sweden, Canada and Italy, is that the black coats are the result of historical matings between black dogs and wild... view more... (2009-02-06)
New open-source software permits faster desktop computer simulations of molecular motion
Whether vibrating in place or taking part in protein folding to ensure cells function properly, molecules are never still. Simulating molecular motions provides researchers with information critical to designing vaccines and helps them decipher the bases of certain diseases, such as Alzheimer's and Parkinson's, that result from molecular motion... view more... (2009-02-05)
Neural mapping paints a haphazard picture of odor receptors
Despite the striking aromatic differences between coffee, peppermint, and pine, a new mapping of the nose's neural circuitry suggests a haphazard patchwork where the receptors for such disparate scents are as likely as not to be neighbors. view more (2009-02-04)
Researchers disrupt biochemical system involved in cancer, degenerative disease
Screening a chemical library of 200,000 compounds, researchers at UT Southwestern Medical Center have identified two new classes that can be used to study and possibly manipulate a cellular pathway involved in many types of cancer and degenerative diseases. view more (2009-02-02)
Researchers Identify New Function of Protein in Cellular Respiration
Virginia Commonwealth University researchers have found that the protein Stat3 plays a key role in regulating mitochondria, the energy-producing machines of cells. This discovery could one day lead to the development of new treatments for heart disease to boost energy in failing heart muscle or to master the abnormal metabolism of cancer. view more (2009-01-29)
DASNR researchers make breakthrough against poxviruses
Smallpox has a nasty history throughout the world. Caused by poxviruses, smallpox is one of the few disease-causing agents against which the human body's immune system is ineffective in its defense. view more (2009-01-26)
Fluorescent proteins illuminating biomedical research
Remarkable new tools that spotlight individual cellular molecules are transforming biomedical research. Scientists at the Gruss Lipper Biophotonics Center at the Albert Einstein College of Medicine of Yeshiva University have spearheaded their use in a series of papers, including one published today in the online version of Nature Methods. view more (2009-01-26)
Mixing genomics and geography yields insights into life and environment
In an upcoming issue of Proceedings of the National Academy of Sciences, Yale researchers used newly developed mathematical models to analyze huge amounts of data on physical characteristics such as temperature and salinity in different ocean habitats and metabolic activity in marine micro-organisms. view more (2009-01-23)
Scientists Unlock Possible Aging Secret in Genetically Altered Fruit Fly
Brown University researchers have identified a cellular mechanism that could someday help fight the aging process. view more (2009-01-23)
New imaging method lets scientists 'see' cell molecules more clearly
Scientists have always wanted to take a closer look at biological systems and materials. From the magnifying glass to the electron microscope, they have developed ever-increasingly sophisticated imaging devices. view more (2009-01-21)
Surviving dance club music (noise) with hearing intact
By tweaking a system in the ear that limits how much sound is heard, a global team of researchers has discovered one alteration that shows that the ability of the ear to turn itself down contributes to protecting against permanent hearing loss. The report appears this week in PLoS Biology. view more (2009-01-21)
Key protein that may cause cancer cell death identified
Researchers at A*STAR's Institute of Molecular and Cell Biology (IMCB) have become the first to discover and characterize a human protein called Bax-beta (Baxβ), which can potentially cause the death of cancer cells and lead to new approaches in cancer treatment. view more (2009-01-20)
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