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Leeds researchers reshape the future of drug discovery
Scientists in Leeds have devised a new way to create the next generation of man-made molecules in a breakthrough that could revolutionise drug development.   view more (2008-11-19)

Scientists exploring new compounds to target muscular dystrophy
Scientists have identified a promising set of new compounds in the fight against muscular dystrophy.   view more (2008-11-19)

New imaging technique tracks cancer-killing cells over prolonged period
Coaxing a patient's own cells to hunt down and tackle infected or diseased cells is a promising therapeutic approach for many disorders.   view more (2008-11-18)

Gold nanostar shape of the future
Rods, cones, cubes and spheres - move aside. Tiny gold stars, smaller than a billionth of a meter, may hold the promise for new approaches to medical diagnoses or testing for environmental contaminants.   view more (2008-11-07)

Scripps research scientists identify compounds for stem-cell production from adult cells
In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects.   view more (2008-11-06)

Substance tackles skin cancer from 2 sides
By playing it safe and using a two-pronged attack, a novel designer molecule fights malignant melanoma. It was created and tested by an international team of researchers led by the University of Bonn.   view more (2008-11-03)

Simple chemical procedure augments therapeutic potential of stem cells
Adult stem cells resemble couch potatoes if they hang out and divide in a dish for too long. They get fat and lose key surface proteins, which interferes with their movement and reduces their therapeutic potential. Now, via a simple chemical procedure, researchers have found a way to get these... view more (2008-10-31)

Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
Researchers from Uppsala University have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in today's on-line issue of Molecular Cell, have implications in understanding the human disorder Beckwith-Wiedemann syndrome.   view more (2008-10-27)

Scientists close in on method to fight deadly childhood cancer
A multicenter team of researchers, including scientists from the University of Florida, has discovered a way to potentially block the growth of neuroblastoma, a type of cancer responsible for 15 percent of all cancer deaths in children.   view more (2008-10-16)

Gold nanostars outshine the competition
Novel nanoparticles being tested at the National Institute of Standards and Technology (NIST) have researchers seeing stars. In a recent paper, NIST scientists used surface-enhanced Raman spectroscopy (SERS) to demonstrate that gold nanostars exhibit optical qualities that make them superior for... view more (2008-10-16)

Researchers identify promising gene target for neuroblastoma therapy
Researchers at Dana-Farber Cancer Institute have identified a set of previously unknown mutations in a single gene in 8 percent of neuroblastomas, tumors of the nervous system that occur in young children and account for approximately 15 percent of all childhood cancer deaths.   view more (2008-10-16)

Burnham Researchers Turn Cancer Friend into Cancer Foe
Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer.   view more (2008-10-08)

Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye
An atomic-resolution view of an enzyme found only in the eye has given researchers at the University of Washington (UW) clues about how this enzyme, essential to vision, is activated.   view more (2008-10-08)

Many receptor models used in drug design may not be useful after all
It may very well be that models used for the design of new drugs have to be regarded as impractical. This is the sobering though important conclusion of the work of two Leiden University scientists published in Science this week.   view more (2008-10-03)

MS patients have higher spinal fluid levels of suspicious immune molecule
A protein that helps keep immune cells quiet is more abundant in the spinal fluid of patients with multiple sclerosis (MS), further boosting suspicion that the protein, TREM-2, may be an important contributor to the disease.   view more (2008-09-30)

Mayo Clinic discovery may help diabetic gastric problem
Mayo Clinic researchers have found what may provide a solution to one of the more troubling complications of diabetes -- delayed gastric emptying or gastroparesis.   view more (2008-09-26)

Cancer-causing gut bacteria exposed
Normal gut bacteria are thought to be involved in colon cancer but the exact mechanisms have remained unknown. Now, scientists from the USA have discovered that a molecule produced by a common gut bacterium activates signalling pathways that are associated with cancer cells.   view more (2008-09-22)

Simulations help explain fast water transport in nanotubes
By discovering the physical mechanism behind the rapid transport of water in carbon nanotubes, scientists at the University of Illinois have moved a step closer to ultra-efficient, next-generation nanofluidic devices for drug delivery, water purification and nano-manufacturing.    view more (2008-09-17)

Newly discovered molecule promises better treatments for heart attacks, heart surgery
Scientists have discovered a compound that could lead to new treatments for heart attacks as well as methods to protect hearts during open heart surgery and other situations in which blood flow to the heart is interrupted.   view more (2008-09-12)

UT Southwestern: Killing bacteria isn't enough to restore immune function after infection
A bacterial molecule that initially signals to animals that they have been invaded must be wiped out by a special enzyme before an infected animal can regain full health, researchers at UT Southwestern Medical Center have found.   view more (2008-09-11)

Carbon molecule with a charge could be tomorrow's semiconductor
Virginia Tech chemistry Professor Harry Dorn has developed a new area of fullerene chemistry that may be the backbone for development of molecular semiconductors and quantum computing applications.   view more (2008-09-09)

DNA editing tool flips its target
Imagine having to copy an entire book by hand without missing a comma. Our cells face a similar task every time they divide. They must duplicate both their DNA and a subtle pattern of punctuation-like modifications on the DNA known as methylation.   view more (2008-09-04)

Putting the squeeze on nitrogen for high energy materials
Nitrogen atoms like to travel in pairs, hooked together by one of the strongest chemical bonds in nature. By subjecting nitrogen molecules to extreme temperatures and pressures scientists are getting a new understanding of not only nitrogen but other similar molecules, including hydrogen.   view more (2008-09-04)

Blood vessel cells are instructed to form tube-like structures
How do blood vessel cells understand that they should organise themselves in tubes and not in layers? A research group from Uppsala University shows for the first time that a special type of "instructor" molecule is needed to accomplish this. These findings, published in the scientific... view more (2008-08-29)

Why a common treatment for prostate cancer ultimately fails
Some of the drugs given to many men during their fight against prostate cancer can actually spur some cancer cells to grow, researchers have found. The findings were published online this week in a pair of papers in the Proceedings of the National Academy of Sciences.   view more (2008-08-22)
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