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Recent Muscular Dystrophy Current Events | Muscular Dystrophy News

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New insight into the controls on a go-to enzyme
Scientists at St. Jude Children's Research Hospital have gained new insights into regulation of one of the body's enzyme workhorses called calpains.   view more (2008-11-20)

Scientists exploring new compounds to target muscular dystrophy
Scientists have identified a promising set of new compounds in the fight against muscular dystrophy.   view more (2008-11-19)

Red-eyed treefrog embryos actively avoid asphyxiation inside their eggs
Boston University undergraduate Jessica Rogge and associate professor Karen Warkentin, working at the Smithsonian Tropical Research Institute's laboratories in Gamboa, Panama, discovered that frog embryos at a very early developmental stage actively respond to oxygen levels in the egg-as reported... view more (2008-11-03)

Extinct sabertooth cats were social, found strength in numbers, study shows
The sabertooth cat (Smilodon fatalis), one of the most iconic extinct mammal species, was likely to be a social animal, living and hunting like lions today, according to new scientific research. The species is famous for its extremely long canine teeth, which reached up to seven inches in length... view more (2008-10-31)

Scientist clears hurdles for muscular dystrophy therapy
Approximately 250,000 people in the United States have some form of muscular dystrophy. Duchenne muscular dystrophy (DMD) is the most common type of the disease, predominantly affecting males.   view more (2008-10-29)

Study may explain exercise-induced fatigue in muscular dystrophies
A University of Iowa study suggests that the prolonged fatigue after mild exercise that occurs in people with many forms of muscular dystrophy is distinct from the inherent muscle weakness caused by the disease.   view more (2008-10-27)

Mediator in communication between neurons and muscle cells found
A missing piece of the puzzle of how neurons and muscle cells establish lifelong communication has been found by researchers who suspect this piece may be mutated and/or attacked in muscular dystrophy.   view more (2008-10-23)

Study finds value in 'junk' DNA
For about 15 years, scientists have known that certain "junk" DNA -- repetitive DNA segments previously thought to have no function -- could evolve into exons, which are the building blocks for protein-coding genes in higher organisms like animals and plants.   view more (2008-10-17)

More effective treatment identified for common childhood vision disorder
Scientists have found a more effective treatment for a common childhood eye muscle coordination problem called convergence insufficiency (CI).    view more (2008-10-16)

Women recover muscle strength more slowly than men
Women's muscles may require longer, more intensive rehabilitation after bed rest and cast immobilization, as reported today by the Institute for Neuromusculoskeletal Research at the Ohio University College of Osteopathic Medicine (OU-COM).   view more (2008-09-26)

PTC124 shows activity in cystic fibrosis; Phase 2 proof-of-concept data published in Lancet
New phase 2 data published today in The Lancet show that the investigational oral drug PTC124 demonstrates activity in nonsense-mutation cystic fibrosis (CF). The data show that treatment with PTC124 results in statistically significant improvements in the chloride channel function of patients with... view more (2008-08-21)

RNA emerges from DNA's shadow
RNA, the transporter of genetic information within the cell, has emerged from the shadow of DNA to become one of the hottest research areas of molecular biology, with implications for many diseases as well as understanding of evolution.   view more (2008-07-11)

Stanford researchers take first look at working muscle fiber
Using an unusual microscope with a tip the size of a needle, Stanford researchers are now able to look at tiny fibers of working muscles in live humans, with minimum discomfort to the patient-a development patients are sure to welcome.    view more (2008-07-11)

Embryo biopsy does not affect early growth and risk of congenital malformations in PGD/PGS babies
A study of 70 singleton babies born after preimplantation genetic diagnosis and screening has shown that the procedure does not adversely affect their early growth and risk of congenital malformations.   view more (2008-07-08)

Penn researchers gain new insights on spinal muscular atrophy
Researchers from the University of Pennsylvania School of Medicine discovered that the effect of a protein deficiency, which is the basis of the neuromuscular disease spinal muscular atrophy (SMA), is not restricted to motor nerve cells, suggesting that SMA is a more general disorder.   view more (2008-05-30)

RNA Toxicity Contributes to Neurodegenerative Disease, University of Pennsylvania Scientists Say
Expanding on prior research performed at the University of Pennsylvania, Penn biologists have determined that faulty RNA, the blueprint that creates mutated, toxic proteins, contributes to a family of neurodegenerative disorders in humans.   view more (2008-05-22)

Electric shocks can cause neurologic and neuropsychological symptoms
Canadian researchers have shown that an electric shock ranging from 120 to 52,000 volts can cause neurologic and neuropsychological symptoms in humans.   view more (2008-05-16)

New approach to protect the hearts of patients with muscular dystrophy
A team of researchers has recently shown that the administration of sildenafil protects the heart in mice with Duchenne muscular dystrophy.   view more (2008-05-13)

Children more vulnerable to harmful effects of lead
Contrary to prevailing assumptions, children are more vulnerable to the harmful effects of lead exposure at the age of 6 than they are in early childhood, according to a Cincinnati Children's Hospital Medical Center study to be presented May 4 at the annual meeting of the Pediatric Academic... view more (2008-05-05)

Researchers discover molecular basis of a form of muscular dystrophy
A team of French and German researchers report in the May 2008 print issue of The FASEB Journal (http://www.fasebj.org) that people with limb-girdle muscular dystrophy are missing a protein called c-FLIP, which the body uses to prevent the loss of muscle tissue.   view more (2008-04-30)

Cold Spring Harbor Laboratory Scientists Devise Potential Approach To Treat Spinal Muscular Atrophy
In the neuromuscular disease called spinal muscular atrophy, or SMA, a protein deficiency caused by a single gene mutation leads to serious damage in growing nerve cells and the muscles they control.   view more (2008-04-07)

Penn Researchers Identify First Sex Chromosome Gene Involved in Meiosis and Male Infertility
A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity. This is the first study of the genetic causes of infertility that links a... view more (2008-03-17)

Investigational drug tested for preventing muscle fiber death in muscular dystrophy
An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage in Duchenne and other forms of muscular dystrophy (MD).   view more (2008-03-17)

Long-term muscle improvements shown in gene therapy study in mice
Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.   view more (2008-03-11)

Research shows promise for potential new gene therapy strategy for muscle-wasting diseases
Investigators in The Research Institute at Nationwide Children's Hospital have identified the role of a protein that could potentially lead to new clinical treatments to combat musculoskeletal diseases, including Duchenne muscular dystrophy (DMD).   view more (2008-03-11)
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