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Claudin 11 stops the leaks in neuronal myelin sheaths
Devaux and Gow demonstrate how a tight junction protein called claudin 11 makes the neuronal myelin sheath a snug fit.   view more (2008-12-01)

In the war against diseases, nerve cells need their armor
In a new study, researchers at the Montreal Neurological Institute (MNI), McGill University, and the Université de Montréal have discovered an essential mechanism for the maintenance of the normal structure of myelin, the protective covering that insulates and supports nerve cells... view more (2008-11-13)

Multiple sclerosis research charges ahead with new mouse model of disease
A new study highlights the role of a charge-switching enzyme in nervous system deficits characteristic of multiple sclerosis and other related neurological illness.   view more (2008-11-06)

Multiple Sclerosis: new MRI contrast medium enables early diagnosis in animal model
In an animal model of multiple sclerosis (MS), neuroradiologists and neurologists of the University hospitals of Heidelberg and Würzburg have been able to visualize inflammatory tissue damage, most of which had remained unrecognized up to now, with the aid of a new contrast medium,... view more (2008-08-04)

MIT identifies cells for spinal-cord repair
A researcher at MIT's Picower Institute for Learning and Memory has pinpointed stem cells within the spinal cord that, if persuaded to differentiate into more healing cells and fewer scarring cells following an injury, may lead to a new, non-surgical treatment for debilitating spinal-cord injuries.   view more (2008-07-22)

Statins have unexpected effect on pool of powerful brain cells
Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.   view more (2008-07-07)

Best treatment for MS may depend on disease subtype
Animal studies by University of Michigan scientists suggest that people who experience the same clinical signs of multiple sclerosis (MS) may have different forms of the disease that require different kinds of treatment.   view more (2008-07-02)

Resuscitation technique after brain injury may do more harm than good
The current standard practice of giving infants and children 100 percent oxygen to prevent brain damage caused by oxygen deprivation may actually inflict additional harm, researchers at UT Southwestern Medical Center have found.   view more (2008-07-01)

Human stem cells show promise against fatal children's diseases
Scientists have used human stem cells to dramatically improve the condition of mice with a neurological condition similar to a set of diseases in children that are invariably fatal, according to an article in the June issue of the journal Cell Stem Cell.   view more (2008-06-05)

Chemotherapy causes delayed severe neural damage
Cancer treatment with chemotherapeutic agents is often associated with delayed adverse neurological consequences - an occurrence often referred to as "chemobrain" - that may compromise the quality of life of a proportion of cancer survivors.   view more (2008-04-22)

Promising new nanotechnology for spinal cord injury
A spinal cord injury often leads to permanent paralysis and loss of sensation below the site of the injury because the damaged nerve fibers can't regenerate. The nerve fibers or axons have the capacity to grow again, but don't because they're blocked by scar tissue that develops around the injury.   view more (2008-04-03)

Experimental MS drug shows promise, offers new window on disease
A drug therapy currently used to treat non-Hodgkin's lymphoma and rheumatoid arthritis had a significant effect in treating the most common form of multiple sclerosis in a small, short-term clinical trial.   view more (2008-02-14)

NIH scientists detect fatal copper disorder at birth
A test developed by NIH scientists could greatly extend the survival of infants with Menkes disease, a rare, otherwise fatal disorder of copper metabolism.   view more (2008-02-07)

Bone marrow cell transplants help nerve regeneration
A study carried out by researchers at the Kyoto University School of Medicine and published in the current issue of CELL TRANSPLANTATION (Vol.16 No. 8) has shown that when transplanted bone marrow cells (BMCs) containing adult stem cells are protected by a 15mm silicon tube and nourished with... view more (2007-12-05)

Vascular biologists make a significant discovery in neurobiology
Researchers investigating blood vessels at Barts and The London School of Medicine have hit upon a new discovery in neurobiology that could have implications for patients experiencing peripheral nerve disorders.   view more (2007-11-30)

Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson... view more (2007-11-12)

Rutgers University Scientist's Research Reveals Critical Knowledge About the Nervous System
Uncover the neural communication links involved in myelination, the process of protecting a nerve's axon, and it may become possible to reverse the breakdown of the nervous system's electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the... view more (2007-11-07)

Imaging shows structural changes in mild traumatic brain injury
Researchers report that diffusion tensor imaging can identify structural changes in the white matter of the brain that correlates to cognitive deficits even in patients with mild traumatic brain injury.   view more (2007-10-26)

MS that Runs in Families Appears More Severe than Non-Familial MS
Magnetic resonance images (MRI) of a large group of patients with multiple sclerosis has provided the first evidence that those with a history of MS in their families show more severe brain damage than patients who have no close relatives with the disease.   view more (2007-10-12)

Antibody leads to repair of myelin sheath in lab study of multiple sclerosis and related disorders
Mayo Clinic researchers have found that a human antibody administered in a single low dose in laboratory mouse models can repair myelin, the insulating covering of nerves that when damaged can lead to multiple sclerosis and other disorders of the central nervous system.   view more (2007-10-09)

Cell-surface sugar defects may trigger nerve damage in multiple sclerosis patients
Defects on cell-surface sugars may promote the short-term inflammation and long-term neurodegeneration that occurs in the central nervous system of multiple sclerosis patients, according to University of California, Irvine researchers.   view more (2007-09-21)

'Fetal' neurons play role in adult brain
Subplate neurons - once thought to die after directing the wiring of the cerebral cortex or gray matter- remain in the white matter of the adult brain in small numbers and maintain activity, communicating with other neurons in the brain said researchers from Baylor College of Medicine and the... view more (2007-09-12)

New MRI finding sheds light on multiple sclerosis disease progression
Using magnetic resonance (MR) images of the brain, researchers have identified a new abnormality related to disease progression and disability in patients with multiple sclerosis (MS), according to a study published in the August issue of Radiology.   view more (2007-08-28)

DNA vaccine against multiple sclerosis appears safe, potentially beneficial
A newly developed DNA vaccine appears safe and may produce beneficial changes in the brains and immune systems of individuals with multiple sclerosis.   view more (2007-08-14)

First new multiple sclerosis gene found in 30 years
A newly identified gene may hold the promise of guiding future research into therapies for multiple sclerosis in what its discoverers say is the first major genetic advance in 30 years for understanding this nervous system disease.   view more (2007-07-30)
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