Narcolepsy is an autoimmune disorder, Stanford researcher says
Ten years ago, Stanford University School of Medicine scientist Emmanuel Mignot, MD, PhD, and his colleagues made headlines when they identified the culprit behind the sleep disorder narcolepsy. view more (2009-05-04)
Genetic study confirms the immune system's role in narcolepsy
Scientists funded by the National Institutes of Health have identified a gene associated with narcolepsy, a disorder that causes disabling daytime sleepiness, sleep attacks, irresistible bouts of sleep that can strike at any time, and disturbed sleep at night. view more (2009-05-04)
Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms
A study in the April 15 issue of the Journal of Clinical Sleep Medicine is the first to assess the effectiveness of treating sleep disorders in adults with a traumatic brain injury (TBI). Results indicate that treatment may result in the objective resolution of the sleep disorder without improvements in daytime sleepiness or neuropsychological... view more... (2009-04-15)
Combating weight gain caused by antipsychotic treatments
Antipsychotic drugs, such as olanzapine (Zyprexa), risperidone (Risperdal) and quetiapine (Seroquel), are commonly used to treat psychotic disorders like schizophrenia, but also bipolar disorder and even behavioral problems related to dementia. view more (2009-03-26)
PET imaging focuses on medication's purported ability to improve mental performance
Concerned by the growing numbers of people using stimulant medications such as methylphenidate (MP)-either legally or illegally-to improve attention and focus, researchers used positron emission tomography (PET) imaging with the radiotracer fluorodeoxyglucose (FDG) to assess the effects of the drug on brain function in the normal human brain. view more (2008-06-17)
JCSM: A single subjective question can be an effective sleepiness screening tool
A single subjective (SS) question may be an effective screening tool for excessive daytime sleepiness, according to a study published in the April 15 issue of the Journal of Clinical Sleep Medicine (JCSM). view more (2008-04-15)
New study in the journal SLEEP finds a high prevalence of eating disorders in narcoleptics
The majority of patients with narcolepsy/cataplexy experience a number of symptoms of eating disorders, with an irresistible craving for food and binge eating as the most prominent features, according to a study published in the March 1 issue of the journal SLEEP. view more (2008-03-03)
Journal SLEEP: Methylphenidate can have sleep benefits in adults with ADHD
Treatment with methylphenidate (MPH) appears to have beneficial effects on sleep parameters in adults with ADHD, including increased sleep efficiency and a feeling of improved restorative value of sleep, according to a study published in the March 1 issue of the journal SLEEP. view more (2008-03-03)
2 different neural pathways regulate loss and regain of consciousness during general anesthesia
University of Pennsylvania School of Medicine researchers have answered long-running questions about the way that anesthetics act on the body, by showing that the cellular pathway for emerging from anesthesia is different from the one that drugs take to put patients to sleep during operations. view more (2008-01-14)
Practice parameters discuss treatment for narcolepsy, other hypersomnias of central origin
Practice parameters published in the December 1 issue of the journal SLEEP serve as both an update of previous practice parameters for the therapy of narcolepsy and as the first practice parameters to address treatment of other hypersomnias of central origin, including idiopathic hypersomnia, recurrent hypersomnia and hypersomnia due to medical... view more... (2007-12-03)
Hormone links sleep, hunger and metabolism, researchers find
While investigating how the hormone orexin might control sleep and hunger, researchers at UT Southwestern Medical Center have discovered, to their surprise, that it activates a protein, HIF-1, long known to stimulate cancerous tumor growth. view more (2007-11-15)
Fish get insomnia, eyes wide open, say Stanford sleep researchers
Scientists at the Stanford University School of Medicine have hooked a fish that suffers from insomnia in their quest to understand the genetics behind sleep disorders. view more (2007-10-16)
Insomniac fish shed light on the molecular basis of sleep disorders
Sleep disorders are common and poorly understood. In humans, narcolepsy is a sleep disorder associated with sleepiness, abnormal dreaming, paralysis and insomnia. view more (2007-10-16)
Study: Modafinil is effective in treating excessive sleepiness
A study published in the October 15 issue of the Journal of Clinical Sleep Medicine (JCSM) finds that modafinil is well-tolerated in the treatment of excessive sleepiness associated with disorders of sleep and wakefulness such as shift work sleep disorder, obstructive sleep apnea (OSA) and narcolepsy, and does not affect cardiovascular or sleep... view more... (2007-10-15)
Lower metabolism, eating behavior possibly explain the cause of overweight in narcolepsy
A lower metabolism, as well as slight changes in eating behavior, could explain the positive energy balance leading to being overweight in narcolepsy. view more (2007-10-01)
Persons with narcolepsy with cataplexy have low levels of CSF hypocretin-1
Persons with narcolepsy with cataplexy have low levels of cerebrospinal fluid (CSF) hypocretin-1, a protein thought to help regulate sleep and wakefulness, according to a study published in the August 1st issue of the journal SLEEP. view more (2007-08-01)
A low expression of MX2 gene exists in the white blood cells of narcoleptics
The first report to identify the biological markers of narcolepsy using gene expression in white blood cells finds that the MX2 gene, which is relevant to the immune system, is significantly less expressed in narcoleptics compared with normal subjects. view more (2007-08-01)
Brain-boosting pill alleviates post-chemotherapy fogginess
A drug described by some people as a "genius pill" for enhancing cognitive function provided relief to a small group of Rochester breast cancer survivors who were coping with a side effect known as "chemo-brain," according to a University of Rochester Medical Center study. view more (2007-06-04)
UCLA Researchers Discover Link Between Parkinson's and Narcolepsy
Parkinson's disease is well-known for its progression of motor disorders: stiffness, slowness, tremors, difficulties walking and talking. Less well known is that Parkinson's shares other symptoms with narcolepsy, a sleep disorder characterized by sudden and uncontrollable episodes of deep sleep, severe fatigue and general sleep disorder. view more (2007-05-14)
Resemblance between cataplexy during status cataplecticus, normal REM sleep
The first efforts to identify the neural structures and pathways underlying cataplexy during status cataplecticus in a narcoleptic patient, with the use of brain perfusion single photon emission computed tomography (SPECT), have led to the discovery that cataplexy during status cataplecticus, a case of prolonged cataplexy, partially resembles... view more... (2007-02-01)
|
|
