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Research reveals lipids' unexpected role in triggering death of brain cells The lipid that accumulates in brain cells of individuals with an inherited enzyme disorder also drives the cell death that is a hallmark of the disease, according to new research led by St. Jude Children's Research Hospital investigators. view more (2009-11-13)
Statins show dramatic drug and cell dependent effects in the brain Besides their tremendous value in treating high cholesterol and lowering the risk of heart disease, statins have also been reported to potentially lower the risks of other diseases, such as dementia. view more (2009-10-29)
Alzheimer's researchers find high protein diet shrinks brain One of the many reasons to pick a low-calorie, low-fat diet rich in vegetables, fruits, and fish is that a host of epidemiological studies have suggested that such a diet may delay the onset or slow the progression of Alzheimer's disease (AD). view more (2009-10-21)
Study examines treatment for olfactory loss after viral infection Treatment with a glucocorticoid medication, either alone or in combination with Ginkgo biloba, appears to significantly improve the sense of smell in individuals with previous olfactory loss due to upper respiratory infections. view more (2009-10-20)
When Proteins Change Partners Dieter Wolf, M.D., and colleagues at Burnham Institute for Medical Research (Burnham) have illuminated how competition between proteins enhances combinatorial diversity during ubiquitination (the process that marks proteins for destruction). view more (2009-09-14)
Prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases Study shows prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases such as atherosclerosis, diabetes and neurodegeneration. view more (2009-09-14)
Canadian research breakthrough holds promise for development of effective cancer therapies Researchers Dr. Marc Therrien at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, and Dr. Frank Sicheri, at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital in Toronto, have discovered a new target that may be instrumental in the development of new, more effective cancer... view more... (2009-09-03)
Looking at language The study of the neural basis of language has largely focused on regions in the cortex - the outer brain layers thought by many researchers to have expanded during human evolution. view more (2009-08-05)
Barrow researchers identify new brain receptor, possible target for Alzheimer's treatment Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer's disease. view more (2009-07-17)
Mouse model of Parkinson's reproduces nonmotor symptoms The classic symptoms of Parkinson's disease involve tremor, stiffness and slow movements. Over the last decade, neurologists have been paying greater attention to non-motor symptoms, such as digestive and sleep problems, loss of sense of smell and depression. view more (2009-06-23)
SUMO protein guides chromatin remodeler to suppress genes In an in vitro study, led by Grace Gill, PhD, Tufts University School of Medicine, researchers discovered how a protein called SUMO (Small Ubiquitin-related Modifier) guides an enzyme complex that alters the structure of chromatin to regulate expression of genes. view more (2009-04-28)
Creating Ideal Neural Cells for Clinical Use Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation. view more (2009-04-14)
Scientists Develop Method for Comprehensive Proteome Analysis Investigators at Burnham Institute for Medical Research (Burnham) have deciphered a large percentage of the total protein complement (proteome) in Schizosaccharomyces pombe (S. pombe) fission yeast. view more (2009-04-09)
Anesthesia is found to induce hyperphosphorylation of tau at sites related to Alzheimer's disease Scientists from The New York State Office of Mental Retardation and Developmental Disabilities' (OMRDD) New York State Institute for Basic Research in Developmental Disabilities (IBR) report today in the March 2009 issue of the Journal of Alzheimer's Disease that anesthesia induces phosphorylation of tau. view more (2009-03-10)
Experts examine causes, treatment and prevention of glaucoma Although scientists know progressive degeneration of retinal ganglion cells and their axons is the primary cause of glaucoma, researchers have yet to identify a way to stop or prevent the degeneration. view more (2009-03-05)
New study provides further evidence that apple juice can delay onset of Alzheimer's disease A growing body of evidence demonstrates that we can take steps to delay age-related cognitive decline, including in some cases that which accompanies Alzheimer's disease, according to a study published in the January 2009 issue of the Journal of Alzheimer's Disease. view more (2009-01-23)
New study provides further evidence that apple juice can delay onset of Alzheimer's disease A growing body of evidence demonstrates that we can take steps to delay age-related cognitive decline, including in some cases that which accompanies Alzheimer's disease, according to a study published in the January 2009 issue of the Journal of Alzheimer's Disease. view more (2009-01-23)
Researchers genetically link Lou Gehrig's disease in humans to dog disease An incurable, paralyzing disease in humans is now genetically linked to a similar disease in dogs. Researchers from the University of Missouri and the Broad Institute have found that the genetic mutation responsible for degenerative myelopathy (DM) in dogs is the same mutation that causes amyotrophic lateral sclerosis (ALS), the human disease also... view more... (2009-01-22)
Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases A Mayo Clinic-led international consortium has found a mechanism that may help explain Parkinson's and other neurological disorders. view more (2009-01-12)
Mutant proteins result in infectious prion disease in mice A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals. view more (2008-12-08)
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