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New MIT tool probes brain circuits
Researchers at the Picower Institute for Learning and Memory at MIT report in the Jan. 24 online edition of Science that they have created a way to see, for the first time, the effect of blocking and unblocking a single neural circuit in a living animal.   view more (2008-01-25)

Evidence found for genes that affect risk of developing Alzheimer's disease
Through one of the largest studies yet of Alzheimer's disease (AD) patients and their brothers, sisters, and children, researchers at Mayo Clinic Jacksonville have found strong evidence that genes other than the well-known susceptibility risk factor APOE4 influence who is at risk for developing the... view more (2008-01-18)

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway
Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.   view more (2008-01-18)

Einstein researchers discover important clue to the cause of Parkinson's disease
A glitch in the mechanism by which cells recycle damaged components may trigger Parkinson's disease, according to a study by scientists at the Albert Einstein College of Medicine of Yeshiva University.   view more (2008-01-03)

Why fish oil is good for you
It's good news that we are living longer, but bad news that the longer we live, the better our odds of developing late-onset Alzheimer's disease.   view more (2007-12-26)

International scientists tackle obstacles to treating brain disorders
A research team led by scientists at the University of Minnesota Medical School and Oregon Health & Science University have outlined the challenges and made suggestions on how to advance research and improve treatments for brain disorders.   view more (2007-12-21)

Overexcited neurons not good for cell health
Neurotransmitters have consequences. They initiate events that are critical to a healthy life, giving us the ability to move, to talk, to breathe, to think. But that's if the neurotransmitters are getting it right and sending proper signals downstream to muscle cells, neurons or other cells.   view more (2007-12-18)

Research unveils new hope for deadly childhood disease
Investigators at the University of Rochester Medical Center have uncovered a promising drug therapy that offers a ray of hope for children with Batten disease - a rare neurodegenerative disease that strikes seemingly healthy kids, progressively robs them of their abilities to see, reason and move,... view more (2007-12-13)

Neurotransmitters in biopolymers stimulate nerve regeneration
Research reported December 11 in the journal Advanced Materials describes a potentially promising strategy for encouraging the regeneration of damaged central nervous system cells known as neurons.   view more (2007-12-12)

MIT: Missing protein may be key to autism
A missing brain protein may be one of the culprits behind autism and other brain disorders, researchers at MIT's Picower Institute for Learning and Memory report in the Dec. 6 issue of Neuron.   view more (2007-12-06)

UIC chemists characterize Alzheimer's neurotoxin structure
Amyloid plaques, the hallmark of Alzheimer's disease, are clumps of fiber-like misfolded proteins which many experts think cause this devastating neurodegenerative disease.   view more (2007-12-04)

Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease.   view more (2007-11-14)

New technology illuminates protein interactions in living cells
While fluorescence has long been used to tag biological molecules, a new technology developed at Yale allows researchers to use tiny fluorescent probes to rapidly detect and identify protein interactions within living cells while avoiding the biological disruption of existing methods, according to... view more (2007-11-12)

Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
Nematode worms treated with lithium show a 46 percent increase in lifespan, raising the tantalizing question of whether humans taking the mood affecting drug are also taking an anti-aging medication.   view more (2007-10-31)

The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases
A phenomenon considered healthy for cells, such as the accumulation of long chains of glucose (glycogen), which tissues store for energy purposes, is harmful for neurons.   view more (2007-10-22)

St. Jude identifies the specific cell that causes eye cancer, disproving long-held theory
Investigators at St. Jude Children's Research Hospital have identified the cell that gives rise to the eye cancer retinoblastoma, disproving a long-standing principle of nerve growth and development.   view more (2007-10-19)

Relatives of patients with Parkinson's disease risk developing dementia, cognitive impairment
Relatives of patients with Parkinson's disease may have an increased risk of developing dementia or cognitive impairment.   view more (2007-10-09)

Discovery offers hope of halting Motor Neurone Disease progression
Scientists have discovered a causal link between the gene for a small protein involved in the formation of blood vessels and the development of some forms of Motor Neurone Disease.   view more (2007-10-05)

Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
Researchers at Mayo Clinic in Jacksonville have discovered how loss of a gene can lead to accumulation of toxic proteins in the brain, resulting in a common dementia, and they say this mechanism may be important in a number of age-related neurological disorders.   view more (2007-09-28)

New way to diagnose Alzheimer's disease promises earlier treatment
Physicians may be able to detect and treat Alzheimer's Disease (AD) in its earliest stages, when patients are experiencing only mild degrees of cognitive impairment, thanks to new diagnostic criteria proposed by an international group of researchers.   view more (2007-09-17)

Understanding the Noxious cause of Lou Gehrig's disease
There is no known cure for amyotrophic lateral sclerosis (ALS), often known as Lou Gehrig disease and motor neuron disease.   view more (2007-09-14)

U. Iowa team identifies genes that improve survival in mice with ALS
University of Iowa researchers investigating the basic biology of cell signaling have made a discovery that may have therapeutic implications for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.   view more (2007-09-14)

Low level of neuronal receptor linked to mild cognitive impairment and Alzheimer's disease
Results of a new study indicate a strong link between the loss of the neuronal receptor LR11and onset of mild cognitive impairment (MCI), often a harbinger of Alzheimer's disease.   view more (2007-09-05)

Same gene protects from 1 disease, opens door to another
Botanists at Oregon State University have discovered that a single plant gene can cause resistance to one disease at the same time it produces susceptibility to a different disease - the first time this unusual phenomenon has ever been observed in plants.   view more (2007-08-29)

All eukaryotic kinases share 1 common set of substrates
Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death.   view more (2007-08-22)
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