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Gene mutation may influence age at onset of Parkinson's disease
The number of mutations in a gene previously found to be associated with early-onset Parkinson's disease may influence the age at which the condition develops; even individuals who carry just one mutated copy may be more susceptible to Parkinson's disease.   view more (2006-06-13)

Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.   view more (2006-06-09)

Free radical cell death switch identified
Humans and other organisms depend on oxygen to produce the energy required for cells to carry out their normal functions. A cell's engine, the mitochondria, converts oxygen into energy. But this process also leaves a kind of exhaust product known as free radicals.   view more (2006-06-02)

Different forms of amyloid beta in Alzheimer's disease harm neurons in different ways
Researchers at UC Irvine have shown that different forms of amyloid beta lead to neural damage in different ways, leading to an increasingly complex view of amyloid toxicity in the Alzheimer brain.   view more (2006-06-01)

Research suggests cause of neurodegeneration in Huntington's disease
The severe neurodegeneration associated with Huntington's disease may result from molecular mutations that block the transport of nutrients within cells.   view more (2006-05-31)

Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's
Researchers at the Burnham Institute for Medical Research have discovered a mechanistic link between cellular stress caused by free radicals and accumulation of misfolded proteins that lead to nerve cell injury and death in neurodegenerative disorders such as Alzheimer's and Parkinson's Disease.   view more (2006-05-25)

Potential new treatment strategy for Alzheimer's disease and other brain and spinal cord damage
A study led by researchers at the San Francisco VA Medical Center and the University of North Carolina, Chapel Hill has identified several new compounds that could play a role in preventing or treating Alzheimer's disease and other degenerative conditions of the nervous system.   view more (2006-05-19)

Prozac's target revealed
Researchers at Cold Spring Harbor Laboratory on Long Island have identified which among several different kinds of cells in the brain is the chief target of the widely prescribed antidepressant Prozac.   view more (2006-05-16)

Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E
A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.   view more (2006-05-11)

Mutant mice show key autism traits
While the causes of autism remain complex and mysterious, researchers are steadily adding pieces to its intricate puzzle.   view more (2006-05-04)

OHSU research reveals possible future target for delaying or stopping Alzheimer's
Researchers at Oregon Health & Science University's Neurological Sciences Institute (NSI) have located a possible target for future therapies aimed at delaying or stopping Alzheimer's disease.   view more (2006-05-02)

Blood clots may hold key to treating dementia
Spontaneous blood clots or debris from arterial disease in the brain (known as cerebral emboli) may hold the key to preventing or treating dementia, say researchers from the University of Manchester in this week's BMJ.   view more (2006-04-28)

Discoveries should aid research into cause of ALS
Two teams of researchers at Northwestern University have found a novel pathological hallmark of the neurodegenerative disease amyotrophic lateral sclerosis (ALS) at the molecular level.   view more (2006-04-26)

Protein's potential as a regulator of brain activity discovered
UC Irvine researchers have found that a protein best known for building connections between nerve cells and muscle also plays a role in controlling brain cell activity.   view more (2006-04-21)

Seven UK cases of Creutzfeldt-Jakob disease associated with transplanted human tissue
Seven cases of Creutzfeldt-Jakob disease (CJD) associated with transplanted human tissue have occurred in the UK over a period of 33 years, reveals a study published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry.   view more (2006-04-20)

Agent Protects Parkinson's Neurons from Rotenone Toxicity
Researchers at the University at Buffalo affiliated with the New York State Center of Excellence in Bioinformatics and Life Sciences have identified a novel agent that can protect neurons involved in Parkinson's disease from being destroyed by the pesticide rotenone.   view more (2006-04-19)

Study finds a high caloric diet may prevent the progression of amyotrophic lateral sclerosis
A recent study directed by the Mount Sinai School of Medicine suggests a ketogenic- high caloric diet may prevent the progression of Amyotrophic Lateral Sclerosis (ALS).   view more (2006-04-18)

Age-related vision problems may be associated with cognitive impairment
Older patients with advanced age-related macular degeneration and reduced vision may be more likely to also have cognitive impairment, or problems with thinking, learning and memory.   view more (2006-04-11)

Brittlestar provides new model for stem cell research
The brittlestar, Amphiura filiformis, is a close relative of the starfish and can regenerate lost arms in a matter of weeks.   view more (2006-04-10)

New mechanism found for neurodegenerative effects of amphetamines in mice
University of Toronto researchers have discovered a new mechanism for the neurodegenerative effects of amphetamines.   view more (2006-04-06)

"Bad" Enzymes May Wear White Hats After Stroke
Enzymes that can harm the brain immediately after a stroke may actually be beneficial days later, according to new research.   view more (2006-03-29)

MRI study opens door to assessing, preventing dangerous brain iron levels
A magnetic resonance imaging (MRI) study at UCLA opens new doors to assessing and potentially preventing brain iron accumulation associated with risk of developing degenerative brain diseases such as Alzheimer's, Parkinson's and Dementia With Lewy Bodies.   view more (2006-03-27)

New Tools Developed for Studying Neurodegenerative Brain Disorders
Penn State researchers have created an elegantly simple model of an axon-the extension of a neuron that communicates with other neurons-and have used this model to reproduce a change in the axon's shape that is characteristic of neurodegenerative disorders such as Alzheimer's and Parkinson's... view more (2006-03-22)

Common anti-convulsant drug may help slow the progression of dementia
Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia.   view more (2006-03-14)

MIT research holds promise for Huntington's treatment
Researchers at MIT and Harvard Medical School have identified a compound that interferes with the pathogenic effects of Huntington's disease, a discovery that could lead to development of a new treatment for the disease.   view more (2006-03-09)
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