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Claudin 11 stops the leaks in neuronal myelin sheaths
Devaux and Gow demonstrate how a tight junction protein called claudin 11 makes the neuronal myelin sheath a snug fit.   view more (2008-12-01)

New research helps explain genetics of Parkinson's disease
A new study by Narendra et al. suggests that Parkin, the product of the Parkinson's disease-related gene Park2, prompts neuronal survival by clearing the cell of its damaged mitochondria.   view more (2008-11-24)

Bad cholesterol inhibits the breakdown of peripheral fat
he so called bad cholesterol (LDL) inhibits the breakdown of fat in cells of peripheral deposits, according to a study from the Swedish medical university Karolinska Institutet. The discovery reveals a novel function of LDL as a regulator of fat turnover besides its well-established detrimental... view more (2008-11-20)

New molecular insight into vertebrate brain development
In the December 1st issue of G&D, Dr. Fred H. Gage (The Salk Institute for Biological Studies) and colleagues reveal a role for the Hippo signaling pathway in the regulation of vertebrate neural development, identifying new factors - and potential therapeutic targets - that may be involved in... view more (2008-11-18)

Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord
Multiple sclerosis is a disease caused by the loss of the myelinated sheath surrounding the nerve fibers of the spinal cord.   view more (2008-11-13)

General anesthesia for hernia surgery in children and risk of later developmental problems
Children under the age of three who had hernia surgery showed almost twice the risk of behavioral or developmental problems later compared to children who had not undergone the surgery, according to a study by researchers at Columbia University Mailman School of Public Health and the College of... view more (2008-11-10)

Multiple sclerosis research charges ahead with new mouse model of disease
A new study highlights the role of a charge-switching enzyme in nervous system deficits characteristic of multiple sclerosis and other related neurological illness.   view more (2008-11-06)

Apelin hormone injections powerfully lower blood sugar
By injecting a hormone produced by fat and other tissues into mice, researchers report in the November Cell Metabolism that they significantly lowered blood sugar levels in normal and obese mice.   view more (2008-11-05)

Penn Scientists Map Molecular Regulation of Fat-Cell Genetics
A research team led by Mitchell Lazar, MD, PhD, Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has used state-of-the-art genetic technology to map thousands of positions where a molecular "master regulator" of fat-cell... view more (2008-11-05)

UC Davis researchers discover a key to aggressive breast cancer
In trying to find out why HER2-positive breast cancer can be more aggressive than other forms of the disease, UC Davis Cancer Center researchers have surprisingly discovered that HER2 itself is the culprit. By shutting down its own regulator gene, HER2 creates a permissive environment for tumor... view more (2008-10-31)

3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually.   view more (2008-10-29)

Glutamate: Too much of a good thing in schizophrenia?
Is schizophrenia a disorder of glutamate hyperactivity or hypoactivity? While the predominant hypothesis for many years was that schizophrenia was a glutamate deficit disorder, there is growing evidence of glutamate hyperactivity as well.   view more (2008-10-28)

Study links nicotine with breast cancer growth and spread
A study published in Cancer Research, a journal of the American Association for Cancer Research, suggests a possible role for nicotine in breast tumor development and metastases.   view more (2008-10-15)

Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al.   view more (2008-10-14)

Forsyth scientists trigger cancer-like response from embryonic stem cells
Scientists from The Forsyth Institute, working with collaborators at Tufts and Tuebingen Universities, have discovered a new control over embryonic stem cells' behavior.   view more (2008-10-14)

Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al.   view more (2008-10-13)

Biological alternatives to chemical pesticides
With increasing consumer pressure on both farmers and supermarkets to minimise the use of chemical pesticides in fruit and vegetables, a new study, funded by the Economic and Social Research Council (ESRC), looks at why there is currently little use of biological alternatives in the UK.   view more (2008-10-08)

Receptor could halt blinding diseases, stop tumor growth, preserve neurons after trauma
An international team of researchers has discovered what promises to be the on-off switch behind several major diseases.   view more (2008-10-07)

Is there more to prion protein than mad cow disease?
Prion protein, a form of protein that triggers BSE, is associated with other brain diseases in cattle, raising the possibility of a significant increase in the range of prion disease.   view more (2008-09-30)

How memories are made, and recalled
What makes a memory? Single cells in the brain, for one thing. For the first time, scientists at UCLA and the Weizmann Institute of Science in Israel have recorded individual brain cells in the act of calling up a memory, thus revealing where in the brain a specific memory is stored, and how it is... view more (2008-09-08)

Study shows how daughter is different from mother
The mother-daughter relationship can be difficult to understand. Why are the two so different? Now a Northwestern University study shows how this happens. In yeast cells, that is.   view more (2008-08-19)

Protein key to control, growth of blood cells
New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and may lead to better treatments for life-threatening blood diseases.   view more (2008-08-14)

Cognitive problems associated with diabetes duration and severity
Individuals with mild cognitive impairment appear more likely to have earlier onset, longer duration and greater severity of diabetes, according to a report in the August issue of Archives of Neurology, one of the JAMA/Archives journals.   view more (2008-08-12)

Sound adds speed to visual perception
The traditional view of individual brain areas involved in perception of different sensory stimuli-i.e., one brain region involved in hearing and another involved in seeing-has been thrown into doubt in recent years.   view more (2008-08-12)

A new cellular pathway linked to cancer is identified by NYU researchers
In the life of a cell, the response to DNA damage determines whether the cell is fated to pause and repair itself, commit suicide, or grow uncontrollably, a route leading to cancer.   view more (2008-07-25)
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