LSUHSC researcher identifies new target to prevent fatal flu lung complication
Research led by Dr. Jay Kolls, Professor and Chairman of Genetics at LSU Health Sciences Center New Orleans, has identified a therapeutic target for acute lung injury resulting in acute respiratory distress syndrome, a highly fatal complication of influenza infection. view more (2009-09-30)
Body's immune system response to dental plaque varies by gender and race
Will neglecting to brush your teeth damage more than just your smile? Can failing to attack dental plaque increase your risk of heart damage? view more (2009-09-25)
Reactive Oxygen's Role in Metastasis
Researchers at the Burnham Institute for Medical Research (Burnham) have discovered that reactive oxygen species, such as superoxide and hydrogen peroxide, play a key role in forming invadopodia, cellular protrusions implicated in cancer cell migration and tumor metastasis. view more (2009-09-16)
Using insects to test for drug safety
Insects, such as some moths and fruit flies, react to microbial infection in the same way as mammals and so can be used to test the efficiency of new drugs, thereby reducing the need for animal testing. view more (2009-09-08)
Breast cancer intervention reduces depression, inflammation
A psychological intervention for newly diagnosed breast cancer patients with symptoms of depression not only relieves patients' depression but also lowers indicators of inflammation in the blood. view more (2009-09-01)
Genes key to staph disease severity, drug resistance found hitchhiking together
Scientists studying Staphylococcus bacteria, including methicillin-resistant S. aureus (MRSA), have discovered a potent staph toxin responsible for disease severity. view more (2009-08-03)
Stop and smell the flowers -- the scent really can soothe stress
Feeling stressed? Then try savoring the scent of lemon, mango, lavender, or other fragrant plants. view more (2009-07-23)
'First Aid' for Brain Cells Comes From Blood
In acute ischemic stroke, the blood supply to the brain is restricted. Initially, brain cells die from lack of oxygen. view more (2009-04-17)
Strategy Discovered for Fighting Persistent Bacterial Infections
Researchers at National Jewish Health have discovered a promising strategy for destroying the molecular scaffolding that can make Pseudomonas bacterial infections extremely difficult to treat in cystic fibrosis patients, wearers of contact lenses, and burn victims. Jerry Nick, MD, Associate Professor of Medicine at National Jewish Health, and his... view more... (2009-03-24)
No hiding place for infecting bacteria
Scientists in Colorado have discovered a new approach to prevent bacterial infections from taking hold. Writing in the Journal of Medical Microbiology, Dr Quinn Parks and colleagues describe how they used enzymes against products of the body's own defence cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm which... view more... (2009-03-16)
Scientists find gene that modifies severity of cystic fibrosis lung disease
Researchers at Wake Forest University Baptist Medical Center, and colleagues, have identified a gene that modifies the severity of lung disease in people with cystic fibrosis, a lethal genetic condition. The findings open the door to possible new targets for treatment, researchers say. view more (2009-03-04)
New potential therapeutic target discovered for genetic disorder -- Barth syndrome
Researchers at NYU Langone Medical Center may have discovered a new targeted intervention for Barth Syndrome (BTHS). BTHS, a sometimes fatal disease, is a serious genetic disorder occurring predominantly in males that leads to infection or heart failure in childhood. view more (2009-03-03)
Researchers block immune cell rush behind deadly sepsis
Researchers have found a way to block the ability of white blood cells to sprint toward the sites of infection when such speed worsens the damage done by sepsis, the often fatal, whole-body bacterial infection, according to a study published today in the journal Blood. view more (2009-02-25)
Helicobacter pylori can multiply in autophagic vesicles
Helicobacter pylori, a Gram-negative, flagellated, microaerophilic bacterium, can selectively colonize in the human stomach. Its infection is widespread throughout the world, and is present in about 50% of the global human population with 80% in developing countries and 20-50% in industrialized countries. view more (2009-01-28)
Scientists Identify New Congenital Neutropenia Syndrome and Causative Gene Mutation
A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). view more (2009-01-05)
Peering inside the skull of a mouse to solve meningitis mystery
NYU Langone Medical Center scientists and their collaborators at the Scripps Research Institute in La Jolla, Calif., have discovered an unexpected cause for the fatal seizures seen in mice with viral meningitis, an infection of the central nervous system, according to a study published in the journal Nature. view more (2008-12-23)
Lenalidomide safe as single therapy for elderly CLL patients
The oral medication lenalidomide is safe and well-tolerated for elderly patients with chronic lymphocytic leukemia, a group without a well-defined frontline therapy for their disease, researchers from The University of Texas M. D. Anderson Cancer Center reported today at the 50th annual meeting of the American Society of Hematology. view more (2008-12-08)
Statins may prevent miscarriages
Hospital for Special Surgery researchers have found that statins may be able to prevent miscarriages in women who are suffering from pregnancy complications caused by antiphospholipid syndrome (APS), according to a study in mice. view more (2008-10-13)
Leishmaniasis parasites evade death by exploiting the immune response to sand fly bites
Cutaneous leishmaniasis, a disease characterized by painful skin ulcers, occurs when the parasite Leishmania major, or a related species, is transmitted to a mammalian host by the bite of an infected sand fly. view more (2008-08-15)
How flesh-eating bacteria attack the body's immune system
"Flesh-eating" or "Strep" bacteria are able to survive and spread in the body by degrading a key immune defense molecule, according to researchers at the University of California, San Diego, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences. view more (2008-08-14)
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