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Bariatric surgery may resolve liver disease
Obesity is a growing epidemic in the U.S. with a significant increase in prevalence from 15 percent to 32.9 percent from 1980 to 2004. Nonalcoholic fatty liver disease (NAFLD) is an emerging problem related to the obesity epidemic, becoming one of the most common causes of liver disease in the... view more (2008-12-01)

OHSU finds association between Epstein-Barr virus, inflammatory diseases of the mouth
Researchers at Oregon Health & Science University's School of Dentistry (www.ohsu.edu/sod) have found that a significant percentage of dental patients with the inflammatory diseases irreversible pulpitis and apical periodontitis also have the Epstein-Barr virus.   view more (2008-11-11)

Quintet of proteins forms new, early-warning blood test before heart attack strikes
A team of Johns Hopkins biochemists has identified a mixed bag of five key proteins out of thousands secreted into blood draining from the heart's blood vessels that may together or in certain quantities form the basis of a far more accurate early warning test than currently in use of impending... view more (2008-11-10)

How about the feasibility of endoscopic ultrasonography-guided choledochoduodenostomy?
Endoscopic ultrasonography (EUS)-guided biliary drainage for treatment of patients who have obstructive jaundice in cases of failed endoscopic retrograde cholangiopancreatography (ERCP).   view more (2008-11-03)

Mayo Clinic's new imaging technology accurately identifies a broad spectrum of liver disease
A new study shows that an imaging technology developed by Mayo Clinic researchers can identify liver fibrosis with high accuracy and help eliminate the need for liver biopsies. Liver fibrosis is a common condition that can lead to incurable cirrhosis if not treated in time.   view more (2008-11-03)

A potential targets for the prevention or treatment of esophageal carcinoma
Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR.   view more (2008-10-29)

Candidate markers for gastric cancer
The sequencing of the human genome has opened the door for proteomics by providing a sequence-based framework for mining proteomes.   view more (2008-10-29)

A new insight on ethanol-induced gastric mucosa injury
Many people all over the world indulge themselves in drinking, which is correlated to a wide spectrum of medical, psychological, behavioral, and social problems.   view more (2008-10-24)

Novel marker of colon cancer
Colon cancer ranks second of all gastrointestinal malignant tumors, it is one of the leading causes of cancer-related deaths worldwide.   view more (2008-10-24)

Genetic analysis predicts whether liver cancer likely to recur
Researchers are poised to unlock the genetic secrets stored in hundreds of thousands of cancer biopsy samples locked in long-term storage and previously thought to be useless for modern genetic research.   view more (2008-10-16)

How to differentiate macro-regenerative nodules from hepato-carcinoma?
BA, the congenital absence or destruction of intra- or extra-hepatic biliary system, affects about 5 - 10/100 000 live births. End stage liver cirrhosis developed in some BA patients later in life.   view more (2008-10-13)

U of T researchers reveal Epstein-Barr virus protein contributes to cancer
Researchers at the University of Toronto have discovered that the EBNA1 protein of Epstein-Barr virus (EBV) disrupts structures in the nucleus of nasopharyngeal carcinoma (NPC) cells, thereby interfering with cellular processes that normally prevent cancer development.   view more (2008-10-07)

H. Pylori bacteria may help prevent some esophageal cancers
Some bacteria may help protect against the development of a type of esophageal cancer, known as adenocarcinoma, according to a new review of the medical literature. These bacteria, which are called Helicobacter pylori, live in the stomachs of humans.    view more (2008-10-06)

Endoscopic therapy may offer an alternative to surgery
Endoscopic therapy is emerging as an alternative to surgery in patients with esophageal cancer given the low likelihood of spread to the lymph nodes.   view more (2008-10-06)

Extra copies of EGFR gene signal poor prognosis for vulvar cancer
A genetic fingerprint identified in patients with a gynecologic cancer may reveal candidates for targeted therapy.   view more (2008-10-01)

MRI spots DCIS in mice
A new magnetic resonance imaging procedure can detect very early breast cancer in mice, including ductal carcinoma in situ (DCIS), a precursor to invasive cancer. Some of the tumors detected were less than 300 microns in diameter, the smallest cancers ever detected by MRI.   view more (2008-10-01)

Saliva proteins could help detection of oral cancer
Clinicians could detect oral squamous cell carcinoma, a form of oral cancer, using a simple test that detects proteins in saliva, according to a report in the October 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.   view more (2008-10-01)

Molecular imaging technology used in gastric cancer
Modern cancer care is critically dependent on imaging technologies, which are used to detect early tumors and guide their therapy or surgery. Molecular imaging technologies provide information about the functional or metabolic characteristics of malignancies, tumor stage and therapeutical response,... view more (2008-09-25)

The small cell neuroendocrine carcinoma of the ampulla of vater
Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed.   view more (2008-09-25)

How to select anti-hepatitis B virus agents for drug-resistance patients?
HBV infection may lead to acute liver disease, chronic active hepatitis, liver cirrhosis, and hepatocellular carcinoma. Over 350 million people worldwide are estimated to be infected chronically by HBV and are therefore at risk of liver failure, cirrhosis, or hepatocellular carcinoma.   view more (2008-09-25)

Which is more accurate on diagnosis of rectal carcinoma?
The depth of transmural tumor invasion along the rectal wall layers and involvement of the regional lymph nodes constitute major factors in the prognosis of rectal cancer.   view more (2008-09-25)

A new therapeutic option for human hepatocyte cancer
p53-impaired tumors may be particularly suitable to parvovirus H-1-induced therapy. Although the p53 deficiency in tumors may induce resistance to chemotherapeutic agents, this will not affect the tumor cell susceptibility to H-1 PV-induced oncolytic infections.   view more (2008-09-24)

Is Bcl-2 protein a major obstacle in treating colorectal carcinoma?
Apoptosis resistance has been shown to contribute to the development of different cancer entities, such as colorectal carcinoma (CRC).   view more (2008-09-24)

Pitt research indicates new virus is culprit, not bystander, in deadly skin cancer
University of Pittsburgh scientists are uncovering more evidence that a virus they recently discovered is the cause of Merkel cell carcinoma, an aggressive and deadly form of skin cancer.   view more (2008-09-23)

What induce local recurrence of rectal carcinoma?
It is well known that local recurrence is the most important prognostic factor of rectal carcinoma. However, even after undergoing radical resection of primary tumors and lymph nodes, about 4%-50% of patients with rectal carcinoma were reportedly with local recurrence.   view more (2008-09-22)

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