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Antioxidants offer pain relief in patients with chronic pancreatitis
Antioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), reports a new study in Gastroenterology.   view more (2009-01-05)

Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis?
Severe acute pancreatitis (SAP) remains a lethal disease. It is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi-organ involvement inducing multi-organ dysfunction syndrome (MODS) with an increased mortality rate.   view more (2008-12-30)

Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis?
Severe acute pancreatitis (SAP) remains a lethal disease. It is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi-organ involvement inducing multi-organ dysfunction syndrome (MODS) with an increased mortality rate.   view more (2008-12-29)

UIC researchers hunting drugs for devastating parasitic disease
Hundreds of millions of people, mainly in developing countries, are disabled by infectious diseases, according to the World Health Organization.   view more (2008-12-17)

Jefferson Department of Surgery announces new pancreas tumor registry
Charles J. Yeo, M.D., Samuel D. Gross Professor and Chair, Department of Surgery at Jefferson Medical College of Thomas Jefferson University, announces the establishment of the new Jefferson Pancreas Tumor Registry (JPTR).   view more (2008-10-30)

Death rate 70 percent lower at top-rated hospitals: HealthGrades annual hospital quality study
Patients have on average a 70 percent lower chance of dying at the nation's top-rated hospitals compared with the lowest-rated hospitals across 17 procedures and conditions analyzed in the eleventh annual HealthGrades Hospital Quality in America Study, issued today by HealthGrades, the leading... view more (2008-10-14)

Why could ethyl pyruvate attenuate severe acute pancreatitis?
Excessive activation of inflammatory mediator cascade during SAP is a major cause of distant organ injury and the high mortality.    view more (2008-10-13)

New studies on the Mediterranean diet confirm its effectiveness for chronic disease prevention
Scientists of the Instituto de Nutrición y Tecnología de los Alimentos (Institute of Nutrition and Food Technology) of the University of Granada (UGR, Spain) have been doing research into the positive effects of Mediterranean diet's ingredients on health.   view more (2008-09-08)

Cellular self-eating promotes pancreatitis
To survive tough times, cells sometimes resort to a form of self-cannibalism called autophagy. But as Hashimoto et al. reveal, autophagy can have a down side, destroying the pancreas by prematurely activating a digestive enzyme.    view more (2008-06-30)

Gene Therapy Could Save Kids From a Lifetime of Eating Cornstarch
A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers.   view more (2008-03-13)

Combined stenting and photodynamic therapy improves survival in late stage liver cancer patients
A combined therapeutic approach of stenting and photodynamic therapy may improve survival rates for patients suffering from advanced liver bile duct cancer, according to a study published this month in Clinical Gastroenterology and Hepatology, the official journal of the American... view more (2008-03-12)

Early surgical treatment contributes to better outcomes in gallstone pancreatitis cases
Although delaying surgical treatment remains the standard of care for patients with severe gallstone pancreatitis, a new study published in the December issue of the Journal of the American College of Surgeons shows that, contrary to widespread belief, early cholecystectomy -- or surgical removal... view more (2007-12-19)

The most important candidate genes for pancreatic stone formation
Stone formation is an important feature of chronic pancreatitis, especially tropical calcific pancreatitis (TCP), where the stones are large in size, highly irregular in shape and cause enormous tissue destruction.   view more (2007-11-14)

Antegrade bowel intussusception can cause recurrent, chronic postoperative intestinal obstruction
Several complications can be seen after pancreatic surgery, most notably bleeding, infections and anastomotic dehiscence. Bowel obstruction can also be seen due to internal hernias or anastomotic strictures. A more unusual etiology for bowel obstruction in this setting is intussusception.   view more (2007-11-14)

Large dose dexamethasone plays important roles in severe acute pancreatitis
Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 - 30% mortality, mainly due to multiple organ failure at its early stage.   view more (2007-11-05)

Exclusion of common bile duct stones prior to gallstone operations
CBDS occur in 7-20% of all patients undergoing a gallstone operation and may complicate the course of surgery. Although intraoperative x-ray investigation was routinely performed to diagnose CBDS in the pre-laparoscopic era, its use during the laparoscopic era has been debated.   view more (2007-10-31)

Acute pancreatitis and cholangitis: a complication caused by a migrated gastrostomy tube
Percutaneous endoscopic gastrostomy (PEG) is generally considered to be safe with a low rate of serious complications. However, dislocation of a gastrostomy tube can lead to serious complications.   view more (2007-10-25)

Short-term hemofiltration is cost-effective for severe acute pancreatitis
Early nasogastric enteral nutrition is a breakthrough in the management of severe acute pancreatitis. From meta-analysis based on current available clinical studies early nasogastric enteral nutrition appeared effective and safe in clinical practice.   view more (2007-10-15)

New minimally invasive sampling technique allows for earlier diagnosis of pancreatic cancer
A new optical technology, coupled with routine endoscopy, may enable doctors to detect the subtle tell-tale traces of early pancreatic cancer.   view more (2007-08-02)

Shining light on pancreatic cancer
Using novel light-scattering techniques, researchers have found the first evidence that early stage pancreatic cancer causes subtle changes in part of the small intestine.   view more (2007-08-01)

Gene therapy eradicates pancreatic cancer in preclinical trial
A molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumors, inhibits metastasis, and prolongs survival with virtually no toxicity.   view more (2007-07-10)

Trial Supports Use of Marker to Predict How Pancreatic Cancer Patients Do After Surgery, Jefferson Surgeon Finds
A team of researchers, led by surgeons at the Kimmel Cancer Center at Jefferson in Philadelphia, has found further evidence supporting the ability of a protein to predict how well a patient with advanced pancreatic cancer will do after surgery, chemotherapy and radiation.   view more (2007-06-25)

Jefferson pharmacologist says biomarker discovery bodes well for better cancer diagnostics
While new findings from Ohio State University scientists suggest a genetic marker that could help distinguish between chronic pancreatitis and pancreatic cancer and gauge who will do well with cancer treatment, a pharmacologist at the Kimmel Cancer Center at Jefferson in Philadelphia sees the... view more (2007-05-02)

Annual study finds top hospitals have 28 percent lower mortality rate
Patients treated at top-rated hospitals nationwide have nearly a one-third better chance of surviving, on average, than those admitted to all other hospitals, according to a study released today by HealthGrades, the leading independent healthcare ratings company.   view more (2007-01-30)

Study shows risk of acute pancreatitis low with statins
New research reveals that while cholesterol-lowering drugs do increase the risk of painful inflammation of the pancreas, the side effect is relatively rare, according to Sonal Singh, M.D., from Wake Forest University School of Medicine, and colleagues.   view more (2007-01-02)

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