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Scientists watch as peptides control crystal growth with 'switches, throttles and brakes'
By producing some of the highest resolution images of peptides attaching to mineral surfaces, scientists have a deeper understanding how biomolecules manipulate the growth crystals. This research may lead to a new treatment for kidney stones using biomolecules.   view more (2009-11-24)

An atomic-level look at an HIV accomplice
Since the discovery in 2007 that a component of human semen called SEVI boosts infectivity of the virus that causes AIDS, researchers have been trying to learn more about SEVI and how it works, in hopes of thwarting its infection-promoting activity.   view more (2009-11-20)

Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor
This research validates the potential for Stapled Peptides to modulate key intracellular biological targets, such as transcription factors, that have not been addressable with current small molecule or biologic drug modalities.   view more (2009-11-12)

Researchers 'notch' a victory toward new kind of cancer drug
Scientists have devised an innovative way to disarm a key protein considered to be "undruggable," meaning that all previous efforts to develop a drug against it have failed.   view more (2009-11-12)

UM Scientists Create Fruit Fly Model to Help Unravel Genetics of Human Diabetes
As rates of obesity, diabetes, and related disorders have reached epidemic proportions in the US in recent years, scientists are working from many angles to pinpoint the causes and contributing factors involved in this public health crisis.   view more (2009-11-03)

Aggressive microdermabrasion induces wound-healing response in aging skin
Microdermabrasion using a coarse diamond-studded instrument appears to induce molecular changes in the skin of older adults that mimic the way skin is remodeled during the wound healing process.   view more (2009-10-20)

'Spaghetti' scaffolding could help grow skin in labs
Scientists are developing new scaffolding technology which could be used to grow tissues such as skin, nerves and cartilage using 3D spaghetti-like structures.   view more (2009-10-16)

Infant pain, adult repercussions
Scientists at Georgia State University have uncovered the mechanisms of how pain in infancy alters how the brain processes pain in adulthood.   view more (2009-09-28)

University of Iowa scientists use blood-brain barrier as therapy delivery system
The blood brain barrier is generally considered an obstacle to delivering therapies from the bloodstream to the brain. However, University of Iowa researchers have discovered a way to turn the blood vessels surrounding brain cells into a production and delivery system for getting therapeutic molecules directly into brain cells.   view more (2009-09-22)

Researchers induce HIV-neutralizing antibodies that recognize HIV-1 envelope protein, lipids
For the first time, researchers have experimentally induced antibodies that neutralize HIV-1 and simultaneously recognize both HIV-1 envelope protein and lipids.   view more (2009-09-02)

Small peptide found to stop lung cancer tumor growth in mice
In new animal research done by investigators at Wake Forest University School of Medicine, scientists have discovered a treatment effective in mice at blocking the growth and shrinking the size of lung cancer tumors, one of the leading causes of cancer death in the world.   view more (2009-08-27)

Reexamination of T. rex verifies disputed biochemical remains
A new analysis of the remains of a Tyrannosaurus rex (T. rex) that roamed Earth 68 million years ago has confirmed traces of protein from blood and bone, tendons, or cartilage.   view more (2009-07-29)

Caltech chemists say antibody surrogates are just a 'click' away
Chemists at the California Institute of Technology (Caltech) and the Scripps Research Institute have developed an innovative technique to create cheap but highly stable chemicals that have the potential to take the place of the antibodies used in many standard medical diagnostic tests.   view more (2009-07-10)

Alzheimer's research yields potential drug target
Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer's disease. Scientists say the discovery may lead to new drugs for the disease.   view more (2009-07-02)

Making nanoparticles in artificial cells
Two new construction manuals are now available for the world's smallest lamps. Based on these protocols, scientists from the Max Planck Institute of Colloids and Interfaces have tailor-made nanoparticles that can be used as position lights on cell proteins and, possibly in the future as well, as light sources for display screens or for optical... view more... (2009-06-29)

Are angiotensins involved in the hemodynamic changes of cirrhosis patients?
Liver cirrhosis has been recently studied in the light of the new view of the renin angiotensin system (RAS).   view more (2009-06-12)

Scripps research team creates simple chemical system that mimics DNA
A team of Scripps Research scientists has created a new analog to DNA that assembles and disassembles itself without the need for enzymes.   view more (2009-06-12)

Study shows animal mating choices more complex than once thought
When female tiger salamanders choose a mate, it turns out that size does matter - tail size that is - and that's not the only factor they weigh.    view more (2009-06-09)

Comprehensive genetic study paves way for new blood-pressure medicines
Eight previously unknown genes that affect blood pressure were recently identified in a comprehensive international study comprising 34,433 Europeans.   view more (2009-05-11)

Study reveals current multi-component vaccines may need reworking
Current strategies for designing vaccines against HIV and cancers, for instance, may enable some components in multi-component vaccines to cancel the effect of others on the immune system, eliminating their ability to provide protection, according to an article to be published shortly in the Proceedings of the National Academy of Sciences (PNAS).   view more (2009-05-08)
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