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Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. view more (2009-11-23)
Sweet -- sugared polymer a new weapon against allergies and asthma
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks. view more (2009-11-20)
TGen seeks emergency FDA approval of new swine flu test
The Phoenix-based non-profit Translational Genomics Research Institute (TGen) announced today that, along with a business collaborator, it will submit a request to the U.S. Food and Drug Administration for emergency use of a new test to diagnose the 2009 H1N1 swine flu virus. view more (2009-10-30)
Triple-Combo Drug Shows Promise Against Antiviral-Resistant Swine Flu, UAB Researcher Says
An experimental drug cocktail that includes three prescriptions now widely available offers the best hope in developing a single agent to treat drug-resistant H1N1 swine flu, says a virology researcher in the University of Alabama Birmingham (UAB) Division of Pediatric Infectious Diseases. view more (2009-10-28)
RNA interference found in budding yeasts
Some budding yeast species have the ability to silence genes using RNA interference (RNAi). Until now, most researchers thought that no budding yeasts possess the RNAi pathway because Saccharomyces cerevisiae, the protoypical model budding yeast does not. view more (2009-09-11)
Fine-tuning an anti-cancer drug
Cancer remains a deadly threat despite the best efforts of science. New hopes were raised a few years ago with the discovery that the uncontrolled growth of cancer cells could be thwarted by blocking the action of proteasomes. view more (2009-08-19)
Advances in lung cancer research announced at conference
Dr. Glen Weiss of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare this week announced two significant advances in treating lung cancer at an international cancer research conference. view more (2009-08-10)
New insights into health and environmental effects of carbon nanoparticles
A new study raises the possibility that flies and other insects that encounter nanomaterial "hot spots," or spills, near manufacturing facilities in the future could pick up and transport nanoparticles on their bodies, transferring the particles to other flies or habitats in the environment. view more (2009-08-06)
Antibiotics, antimicrobials and antifungals in waterways
Antibiotics, antimicrobials and antifungals are seeping into the waterways of North America, Europe and East Asia, according to an investigation published in the peer-reviewed journal Environmental Health Perspectives (EHP). view more (2009-06-10)
Scientists develop a new HIV microbicide -- and a way to mass produce it in plants
In what could be a major pharmaceutical breakthrough, research published online in The FASEB Journal describes how scientists from St George's, University of London have devised a one-two punch to stop HIV. view more (2009-05-29)
Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML
Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today. view more (2009-03-27)
Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML
Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today. view more (2009-03-26)
New form of intravenous iron treats anemia in chronic kidney disease patients on dialysis
Ferumoxytol, a novel intravenous form of iron that permits rapid administration of large doses, has been shown to be effective for treating iron deficiency in chronic kidney disease (CKD) patients on dialysis, according to a clinical trial appearing in the February 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN). view more (2009-01-28)
Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment
Researchers from Joslin Diabetes Center, Boston, and ActiveSite Pharmaceuticals, Inc., San Francisco, announced today that they have demonstrated that a specific inhibitor of the protease plasma kallikrein, ASP-440, developed by ActiveSite Pharmaceuticals, may provide a new therapeutic approach for treatment of diabetic retinopathy, the most... view more... (2009-01-22)
1 step closer to green chemistry and improved pharmaceuticals
Proteins are the workhorses of our cells. They help to digest our food, are at the core of our immune system, and literally shape our body from top to toe. view more (2008-06-25)
Investigators unveil new drug discovery tool for Alzheimer's disease
An article published in the April issue of the Journal of Alzheimer's Disease presents a detailed characterization of a new drug discovery tool for Alzheimer's disease. view more (2008-04-29)
MSU study finds media coverage of breast cancer focuses too little on prevention
News coverage of breast cancer focuses too much on treatments and not enough on prevention, a trend that could prove risky in the long run for many women, say researchers at Michigan State University. view more (2008-04-16)
Cystic Fibrosis Foundation announces positive early results for phase 2 clinical trial of VX-770
The Cystic Fibrosis Foundation announced today that VX-770, an oral drug in development that targets a basic defect in CF, showed promising results in an ongoing Phase 2a clinical trial for patients who carry the G551D mutation of CF. The drug is being developed by Vertex Pharmaceuticals Incorporated. view more (2008-03-28)
Stanford researchers publish review of US medical device regulation
Researchers at the Stanford University Program in Biodesign have released a review of the background, mission and statutory requirements of medical device regulation in the United States. view more (2008-01-11)
Researchers challenge previous findings regarding widely used asthma treatment
A new study published recently in The Lancet reveals that one of the most commonly used asthma medicines -- long-acting beta-agonists -- may not be associated with adverse events in people based on their genotype (gene variation), as previous studies had shown. view more (2008-01-11)
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