Recent Pharmacology Current Events | Pharmacology News | 3
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Nicotine addiction slashed in test of new cigarette smoking strategy
Scientists are reporting the first successful strategy to reduce smokers' nicotine dependence while allowing them to continue smoking. The study provides strong support for proposals now being considered in Congress to authorize FDA regulation of cigarette smoking, according to the research team. view more (2007-11-14)
Possible safer target for anti-clotting drugs found
Researchers at the University of Illinois at Chicago College of Medicine have identified a new molecular target in blood clot formation, which seems to reduce clotting without excessive bleeding, the common side-effect of anti-clotting agents. view more (2007-09-27)
Research elucidates mechanism by which gene expression may be altered in drug addiction
Dr. Judith A. Potashkin, Ph.D. and her colleagues at Rosalind Franklin University of Medicine and Science recently completed a study investigating one of the changes in gene expression that occurs when individuals take addictive drugs. view more (2007-09-05)
Vitamin E's lack of heart benefit linked to dosage
The reported failure of vitamin E to prevent heart attacks may be due to underdosing, according to a new study by investigators at Vanderbilt University Medical Center. view more (2007-08-23)
Key to out-of-control immune response in lung injury found
Researchers at the University of Illinois at Chicago College of Medicine have discovered how a protein modulates the inflammatory response in sudden, life-threatening lung failure. The protein's previously unknown role is reported in the August issue of Nature Medicine. view more (2007-08-17)
Would you like fries with that?
Exploiting interactions between food and drugs could dramatically lower the rapidly rising costs of several anticancer drugs, and perhaps many other medications, two cancer-pharmacology specialists suggest in a commentary in the July 16, 2007, issue of the Journal of Clinical Oncology. view more (2007-07-17)
Cholesterol drug hits diabetes with one-two punch, Tulane study says
Patients with type 2 diabetes may soon be able to control their glucose and their cholesterol levels with a single drug. view more (2007-07-09)
Substance in tree bark could lead to new lung-cancer treatment
Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer. view more (2007-06-26)
Study of the drug, Isradipine, to determine if it slows or prevents Parkinson's disease
Gloria E. Meredith, Ph.D., collaborated with D. James Surmeier, Ph.D. and other scientists at Northwestern University to study the drug, Isradipine, and its possible effects on Parkinson's disease. view more (2007-06-14)
Personal drug selection: Problem-based learning in pharmacology
Irrational use of medicines is a major problem all over the world. The World Health Organization (WHO) and many other bodies are concentrating on improving the use of medicines. view more (2007-06-13)
Menthol receptor also important in detecting cold temperatures
The ion channel activated by menthol also detects a wide range of cold temperatures and relays the information to the brain, according to a study in Nature by Yale School of Medicine, the University of California at San Francisco (UCSF), and the University of Wisconsin. view more (2007-06-08)
Study implicates protein as a trigger of advanced prostate cancer recurrence
Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens. view more (2007-05-09)
OHSU lab finds meth receptor that could lead to therapy
A recently discovered signaling system in the brain has just been shown to be turned on by methamphetamine, an Oregon Health & Science University study found. view more (2007-04-19)
Bleeding during endoscopy: Do anti-inflammatories play a role?
Does an aspirin-a-day increase the risk of bleeding during invasive diagnostic procedure? This is an important concern for many patients who take these and other antiplatelet agents in an effort to reduce heart attacks or strokes. view more (2007-03-16)
Prenatal cocaine's lasting cellular effects
Although the "crack baby" hysteria of the 1980s was greatly exaggerated, cocaine use during pregnancy can cause subtle but disabling cognitive impairments — attention deficits, learning disabilities and emotional problems. view more (2007-01-15)
Dartmouth researchers find that arsenic triggers unique mechanism in rare leukemia
Dartmouth Medical School (DMS) researchers have identified a new way that arsenite, a form of arsenic, acts in treating a rare cancer known as APL, or acute promyelocytic leukemia. Their study is published in the Jan. 3 issue of the Journal of the National Cancer Institute. view more (2007-01-09)
Scientists Uncover Potential Key to Brain Blood-Flow Disorders
Scientists at the University of Vermont have clarified the cellular process responsible for signaling regional blood flow changes in the brain, thereby uncovering possible causes for such disorders as stroke, migraine, and Alzheimer's disease. view more (2007-01-04)
The Journal of Clinical Pharmacology looks at effects of smoking cessation drug, varenicline
Smoking is the world's leading cause of premature death. Smokers who quit are able to significantly reduce their risk of premature death and other health issues - almost completely if they quit by age thirty and by fifty percent if they quit after age fifty. view more (2006-11-01)
Molecular 'signature' protects cells from viruses
Every cell constantly produces a whole arsenal of proteins. The instruction what is to be built comes from the cell nucleus: this is where the DNA is stored, the heredity molecule in which, so to speak, the construction blueprints for all cellular proteins are stored. view more (2006-10-13)
Molecule helps cells plug leaks following lung injury
Researchers at the University of Illinois at Chicago College of Medicine have identified a molecule that plays a critical role in the recovery of lung tissue following severe injury. view more (2006-09-15)
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