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Cancers' Sweet Tooth May Be Weakness The pedal-to-the-metal signals driving the growth of several types of cancer cells lead to a common switch governing the use of glucose, researchers at Winship Cancer Institute of Emory University have discovered. view more (2009-11-19)
Mouse gene suppresses Alzheimer's plaques and tangles Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. view more (2009-11-12)
The food-energy cellular connection revealed Our body's activity levels fall and rise to the beat of our internal drums-the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. view more (2009-10-16)
A balancing act in Parkinson's disease: Phosphorylation of alpha-synuclein Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease. view more (2009-10-13)
Researchers identify 1 of the necessary processes in the formation of long-term memory A new study that was carried out at the University of Haifa has identified another component in the chain of actions that take place in the neurons in the process of forming memories. view more (2009-09-08)
Researchers identify new, cancer-causing role for protein The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 28 edition of Science. view more (2009-08-28)
What makes stem cells tick? Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. view more (2009-08-07)
Unraveling how cells respond to low oxygen Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. view more (2009-08-06)
Building memories with actin Memories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. view more (2009-07-13)
Protein can help cells or cause cancer, Purdue researcher finds A Purdue University scientist has discovered a key process in cell growth that can lead to the formation of tumors. view more (2009-07-08)
New Piece Found in the Puzzle of Epigenetics A team of scientists led by Professor Dirk Eick of Helmholtz Zentrum München has identified the enzyme TFIIH kinase as an important factor in the epigenetic regulation of the cell nucleus enzyme RNA polymerase II. view more (2009-06-17)
Discovery of the cell's water gate may lead to new cancer drugs The flow of water into and out from the cell may play a crucial role in several types of cancer. Scientists at the University of Gothenburg have now found the gate that regulates the flow of water into yeast cells. view more (2009-06-17)
Tribble 3 can induce non-alcoholic fatty liver disease? Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. view more (2009-06-11)
Biological Timekeeper Studies Reveal New Temperature Regulator and Track Clock Protein across a Day Dartmouth Medical School geneticists have made new inroads into understanding the regulatory circuitry of the biological clock that synchronizes the ebb and flow of daily activities. view more (2009-05-18)
New evidence of how high glucose damages blood vessels could lead to new treatments New evidence of how the elevated glucose levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking the destruction, Medical College of Georgia researchers say. view more (2009-05-12)
New hope for treatment of neurodegenerative disorder Researchers from the University of Southern California have taken an important first step toward protecting against Huntington disease using gene therapy. view more (2009-04-21)
New alternative to biopsy detects subtle changes in cancer cells, Stanford study shows A drop of blood or a chunk of tissue smaller than the period at the end of this sentence may one day be all that is necessary to diagnose cancers and assess their response to treatment, say researchers at the Stanford University School of Medicine. view more (2009-04-13)
New method for detection of phosphoproteins reveals regulator of melanoma invasion Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. view more (2009-04-10)
Is transforming growth factor-beta involved in intestinal wound healing? Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease. Transforming growth factor- beta (TGF- beta) is involved in the regulation of cell migration, cell differentiation, extracellular matrix deposition, and immune responses. view more (2009-03-31)
Anesthesia is found to induce hyperphosphorylation of tau at sites related to Alzheimer's disease Scientists from The New York State Office of Mental Retardation and Developmental Disabilities' (OMRDD) New York State Institute for Basic Research in Developmental Disabilities (IBR) report today in the March 2009 issue of the Journal of Alzheimer's Disease that anesthesia induces phosphorylation of tau. view more (2009-03-10)
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